Duodenal gastrointestinal stromal tumor: case report and importance of ecoendoscopy

Bibliographic Details
Main Author: Santos, Brian França dos
Publication Date: 2021
Other Authors: Lemos Junior, Vilson de, Lino, Juliana Ribeiro da Costa, Leite, Cleber Queiroz
Format: Article
Language: por
Source: Research, Society and Development
Download full: https://rsdjournal.org/index.php/rsd/article/view/19407
Summary: Gastrointestinal stromal tumors (GISTs) are generally quite rare, but the same are the mesenchymal neoplasms that are most frequently identified in the gastrointestinal tract (GIT) and represent 0.1 to 3% of all gastrointestinal tumors. The diagnosis of this pathology is made according to the clinical picture, in the morphological characteristics, and fundamentally in the consideration of the presence of the protein c-KIT (CD117) detected by immunohistochemical method. In most cases, these tumors present in the individual asymptomatically, so they are discovered incidentally by imaging exams. The prognostic factors of great importance are the size of the tumor and the mitotic index. Surgical resection is the therapy of choice and imatinib mesylate chemotherapy, which is indicated in cases of unresectability or metastatic disease. We present a case of Duodenal GIST diagnoses by echoendoscopy after an incidental finding during an upper gastrointestinal endoscopy exam.
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spelling Duodenal gastrointestinal stromal tumor: case report and importance of ecoendoscopy Tumor estromal duodenal gastrointestinal: reporte de caso e importancia de la ecoendoscopiaTumor estromal gastrointestinal duodenal: relato de caso e importância da ecoendoscopiaTumor del Estroma GastrointestinalProteína c-KITTracto GastrointestinalUltrasonido.Tumor Estromal GastrointestinalProteína c-KITTrato GastrointestinalEcoendoscopia.Gastrointestinal Stromal TumorC-KIT ProteinGastrointestinal TractEndoscopy ultrasound.Gastrointestinal stromal tumors (GISTs) are generally quite rare, but the same are the mesenchymal neoplasms that are most frequently identified in the gastrointestinal tract (GIT) and represent 0.1 to 3% of all gastrointestinal tumors. The diagnosis of this pathology is made according to the clinical picture, in the morphological characteristics, and fundamentally in the consideration of the presence of the protein c-KIT (CD117) detected by immunohistochemical method. In most cases, these tumors present in the individual asymptomatically, so they are discovered incidentally by imaging exams. The prognostic factors of great importance are the size of the tumor and the mitotic index. Surgical resection is the therapy of choice and imatinib mesylate chemotherapy, which is indicated in cases of unresectability or metastatic disease. We present a case of Duodenal GIST diagnoses by echoendoscopy after an incidental finding during an upper gastrointestinal endoscopy exam.Los tumores del estroma gastrointestinal (GIST) son raros y representan del 0,1 al 3% de todos los tumores gastrointestinales. En la mayoría de los casos, estos tumores se presentan de forma asintomática y se descubren de forma incidental mediante exámenes por imágenes. La ecoendoscopia (USE) se ha utilizado como método de elección para la caracterización de estas lesiones, permitiendo la valoración precisa de su tamaño, capa de origen parietal y diversas características morfológicas. El diagnóstico se realiza por la presencia de la proteína c-KIT (CD117) detectada por el método inmunohistoquímico. Los factores pronósticos de gran importancia son el tamaño del tumor y el índice mitótico. La resección quirúrgica es la terapia de elección y la quimioterapia con mesilato de imatinib está indicada en casos de irresecabilidad o enfermedad metastásica. Presentamos un caso de GIST duodenal diagnosticado por ecoendoscopia tras un hallazgo incidental durante la endoscopia digestiva alta.Os tumores estromais gastrointestinais (GISTs) são raros e representam 0,1 a 3 % de todos os tumores gastrointestinais. Na maioria dos casos esses tumores se apresentam de forma assintomática, sendo descobertos incidentalmente por exames de imagem. A ecoendoscopia (EUS) tem sido utilizada como método de eleição para a caracterização destas lesões, permitindo avaliar com precisão o seu tamanho, camada de origem parietal e diversas características morfológicas. O diagnóstico é feito pela presença da proteína c-KIT (CD117) detectada pelo método imuno-histoquímico. Os fatores prognósticos de grande importância são o tamanho do tumor e o índice mitótico. A ressecção cirúrgica é a terapia de escolha e o tratamento quimioterápico com mesilato de imatinibe está indicado nos casos de irressecabilidade ou doença metastática. Apresentamos um caso de GIST Duodenal diagnosticado pela ecoendoscopia após achado incidental durante exame de endoscopia digestiva alta.Research, Society and Development2021-08-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1940710.33448/rsd-v10i11.19407Research, Society and Development; Vol. 10 No. 11; e124101119407Research, Society and Development; Vol. 10 Núm. 11; e124101119407Research, Society and Development; v. 10 n. 11; e1241011194072525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/19407/17415Copyright (c) 2021 Brian França dos Santos; Vilson de Lemos Junior; Juliana Ribeiro da Costa Lino; Cleber Queiroz Leitehttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSantos, Brian França dos Lemos Junior, Vilson de Lino, Juliana Ribeiro da Costa Leite, Cleber Queiroz 2021-10-23T19:01:11Zoai:ojs.pkp.sfu.ca:article/19407Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:39:18.528479Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false
dc.title.none.fl_str_mv Duodenal gastrointestinal stromal tumor: case report and importance of ecoendoscopy
Tumor estromal duodenal gastrointestinal: reporte de caso e importancia de la ecoendoscopia
Tumor estromal gastrointestinal duodenal: relato de caso e importância da ecoendoscopia
title Duodenal gastrointestinal stromal tumor: case report and importance of ecoendoscopy
spellingShingle Duodenal gastrointestinal stromal tumor: case report and importance of ecoendoscopy
Santos, Brian França dos
Tumor del Estroma Gastrointestinal
Proteína c-KIT
Tracto Gastrointestinal
Ultrasonido.
Tumor Estromal Gastrointestinal
Proteína c-KIT
Trato Gastrointestinal
Ecoendoscopia.
Gastrointestinal Stromal Tumor
C-KIT Protein
Gastrointestinal Tract
Endoscopy ultrasound.
title_short Duodenal gastrointestinal stromal tumor: case report and importance of ecoendoscopy
title_full Duodenal gastrointestinal stromal tumor: case report and importance of ecoendoscopy
title_fullStr Duodenal gastrointestinal stromal tumor: case report and importance of ecoendoscopy
title_full_unstemmed Duodenal gastrointestinal stromal tumor: case report and importance of ecoendoscopy
title_sort Duodenal gastrointestinal stromal tumor: case report and importance of ecoendoscopy
author Santos, Brian França dos
author_facet Santos, Brian França dos
Lemos Junior, Vilson de
Lino, Juliana Ribeiro da Costa
Leite, Cleber Queiroz
author_role author
author2 Lemos Junior, Vilson de
Lino, Juliana Ribeiro da Costa
Leite, Cleber Queiroz
author2_role author
author
author
dc.contributor.author.fl_str_mv Santos, Brian França dos
Lemos Junior, Vilson de
Lino, Juliana Ribeiro da Costa
Leite, Cleber Queiroz
dc.subject.por.fl_str_mv Tumor del Estroma Gastrointestinal
Proteína c-KIT
Tracto Gastrointestinal
Ultrasonido.
Tumor Estromal Gastrointestinal
Proteína c-KIT
Trato Gastrointestinal
Ecoendoscopia.
Gastrointestinal Stromal Tumor
C-KIT Protein
Gastrointestinal Tract
Endoscopy ultrasound.
topic Tumor del Estroma Gastrointestinal
Proteína c-KIT
Tracto Gastrointestinal
Ultrasonido.
Tumor Estromal Gastrointestinal
Proteína c-KIT
Trato Gastrointestinal
Ecoendoscopia.
Gastrointestinal Stromal Tumor
C-KIT Protein
Gastrointestinal Tract
Endoscopy ultrasound.
description Gastrointestinal stromal tumors (GISTs) are generally quite rare, but the same are the mesenchymal neoplasms that are most frequently identified in the gastrointestinal tract (GIT) and represent 0.1 to 3% of all gastrointestinal tumors. The diagnosis of this pathology is made according to the clinical picture, in the morphological characteristics, and fundamentally in the consideration of the presence of the protein c-KIT (CD117) detected by immunohistochemical method. In most cases, these tumors present in the individual asymptomatically, so they are discovered incidentally by imaging exams. The prognostic factors of great importance are the size of the tumor and the mitotic index. Surgical resection is the therapy of choice and imatinib mesylate chemotherapy, which is indicated in cases of unresectability or metastatic disease. We present a case of Duodenal GIST diagnoses by echoendoscopy after an incidental finding during an upper gastrointestinal endoscopy exam.
publishDate 2021
dc.date.none.fl_str_mv 2021-08-25
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/19407
10.33448/rsd-v10i11.19407
url https://rsdjournal.org/index.php/rsd/article/view/19407
identifier_str_mv 10.33448/rsd-v10i11.19407
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv https://rsdjournal.org/index.php/rsd/article/view/19407/17415
dc.rights.driver.fl_str_mv https://creativecommons.org/licenses/by/4.0
info:eu-repo/semantics/openAccess
rights_invalid_str_mv https://creativecommons.org/licenses/by/4.0
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Research, Society and Development
publisher.none.fl_str_mv Research, Society and Development
dc.source.none.fl_str_mv Research, Society and Development; Vol. 10 No. 11; e124101119407
Research, Society and Development; Vol. 10 Núm. 11; e124101119407
Research, Society and Development; v. 10 n. 11; e124101119407
2525-3409
reponame:Research, Society and Development
instname:Universidade Federal de Itajubá (UNIFEI)
instacron:UNIFEI
instname_str Universidade Federal de Itajubá (UNIFEI)
instacron_str UNIFEI
institution UNIFEI
reponame_str Research, Society and Development
collection Research, Society and Development
repository.name.fl_str_mv Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)
repository.mail.fl_str_mv rsd.articles@gmail.com
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