Duodenal gastrointestinal stromal tumor: case report and importance of ecoendoscopy
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Publication Date: | 2021 |
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Format: | Article |
Language: | por |
Source: | Research, Society and Development |
Download full: | https://rsdjournal.org/index.php/rsd/article/view/19407 |
Summary: | Gastrointestinal stromal tumors (GISTs) are generally quite rare, but the same are the mesenchymal neoplasms that are most frequently identified in the gastrointestinal tract (GIT) and represent 0.1 to 3% of all gastrointestinal tumors. The diagnosis of this pathology is made according to the clinical picture, in the morphological characteristics, and fundamentally in the consideration of the presence of the protein c-KIT (CD117) detected by immunohistochemical method. In most cases, these tumors present in the individual asymptomatically, so they are discovered incidentally by imaging exams. The prognostic factors of great importance are the size of the tumor and the mitotic index. Surgical resection is the therapy of choice and imatinib mesylate chemotherapy, which is indicated in cases of unresectability or metastatic disease. We present a case of Duodenal GIST diagnoses by echoendoscopy after an incidental finding during an upper gastrointestinal endoscopy exam. |
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Duodenal gastrointestinal stromal tumor: case report and importance of ecoendoscopy Tumor estromal duodenal gastrointestinal: reporte de caso e importancia de la ecoendoscopiaTumor estromal gastrointestinal duodenal: relato de caso e importância da ecoendoscopiaTumor del Estroma GastrointestinalProteína c-KITTracto GastrointestinalUltrasonido.Tumor Estromal GastrointestinalProteína c-KITTrato GastrointestinalEcoendoscopia.Gastrointestinal Stromal TumorC-KIT ProteinGastrointestinal TractEndoscopy ultrasound.Gastrointestinal stromal tumors (GISTs) are generally quite rare, but the same are the mesenchymal neoplasms that are most frequently identified in the gastrointestinal tract (GIT) and represent 0.1 to 3% of all gastrointestinal tumors. The diagnosis of this pathology is made according to the clinical picture, in the morphological characteristics, and fundamentally in the consideration of the presence of the protein c-KIT (CD117) detected by immunohistochemical method. In most cases, these tumors present in the individual asymptomatically, so they are discovered incidentally by imaging exams. The prognostic factors of great importance are the size of the tumor and the mitotic index. Surgical resection is the therapy of choice and imatinib mesylate chemotherapy, which is indicated in cases of unresectability or metastatic disease. We present a case of Duodenal GIST diagnoses by echoendoscopy after an incidental finding during an upper gastrointestinal endoscopy exam.Los tumores del estroma gastrointestinal (GIST) son raros y representan del 0,1 al 3% de todos los tumores gastrointestinales. En la mayoría de los casos, estos tumores se presentan de forma asintomática y se descubren de forma incidental mediante exámenes por imágenes. La ecoendoscopia (USE) se ha utilizado como método de elección para la caracterización de estas lesiones, permitiendo la valoración precisa de su tamaño, capa de origen parietal y diversas características morfológicas. El diagnóstico se realiza por la presencia de la proteína c-KIT (CD117) detectada por el método inmunohistoquímico. Los factores pronósticos de gran importancia son el tamaño del tumor y el índice mitótico. La resección quirúrgica es la terapia de elección y la quimioterapia con mesilato de imatinib está indicada en casos de irresecabilidad o enfermedad metastásica. Presentamos un caso de GIST duodenal diagnosticado por ecoendoscopia tras un hallazgo incidental durante la endoscopia digestiva alta.Os tumores estromais gastrointestinais (GISTs) são raros e representam 0,1 a 3 % de todos os tumores gastrointestinais. Na maioria dos casos esses tumores se apresentam de forma assintomática, sendo descobertos incidentalmente por exames de imagem. A ecoendoscopia (EUS) tem sido utilizada como método de eleição para a caracterização destas lesões, permitindo avaliar com precisão o seu tamanho, camada de origem parietal e diversas características morfológicas. O diagnóstico é feito pela presença da proteína c-KIT (CD117) detectada pelo método imuno-histoquímico. Os fatores prognósticos de grande importância são o tamanho do tumor e o índice mitótico. A ressecção cirúrgica é a terapia de escolha e o tratamento quimioterápico com mesilato de imatinibe está indicado nos casos de irressecabilidade ou doença metastática. Apresentamos um caso de GIST Duodenal diagnosticado pela ecoendoscopia após achado incidental durante exame de endoscopia digestiva alta.Research, Society and Development2021-08-25info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/1940710.33448/rsd-v10i11.19407Research, Society and Development; Vol. 10 No. 11; e124101119407Research, Society and Development; Vol. 10 Núm. 11; e124101119407Research, Society and Development; v. 10 n. 11; e1241011194072525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIporhttps://rsdjournal.org/index.php/rsd/article/view/19407/17415Copyright (c) 2021 Brian França dos Santos; Vilson de Lemos Junior; Juliana Ribeiro da Costa Lino; Cleber Queiroz Leitehttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessSantos, Brian França dos Lemos Junior, Vilson de Lino, Juliana Ribeiro da Costa Leite, Cleber Queiroz 2021-10-23T19:01:11Zoai:ojs.pkp.sfu.ca:article/19407Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:39:18.528479Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Duodenal gastrointestinal stromal tumor: case report and importance of ecoendoscopy Tumor estromal duodenal gastrointestinal: reporte de caso e importancia de la ecoendoscopia Tumor estromal gastrointestinal duodenal: relato de caso e importância da ecoendoscopia |
title |
Duodenal gastrointestinal stromal tumor: case report and importance of ecoendoscopy |
spellingShingle |
Duodenal gastrointestinal stromal tumor: case report and importance of ecoendoscopy Santos, Brian França dos Tumor del Estroma Gastrointestinal Proteína c-KIT Tracto Gastrointestinal Ultrasonido. Tumor Estromal Gastrointestinal Proteína c-KIT Trato Gastrointestinal Ecoendoscopia. Gastrointestinal Stromal Tumor C-KIT Protein Gastrointestinal Tract Endoscopy ultrasound. |
title_short |
Duodenal gastrointestinal stromal tumor: case report and importance of ecoendoscopy |
title_full |
Duodenal gastrointestinal stromal tumor: case report and importance of ecoendoscopy |
title_fullStr |
Duodenal gastrointestinal stromal tumor: case report and importance of ecoendoscopy |
title_full_unstemmed |
Duodenal gastrointestinal stromal tumor: case report and importance of ecoendoscopy |
title_sort |
Duodenal gastrointestinal stromal tumor: case report and importance of ecoendoscopy |
author |
Santos, Brian França dos |
author_facet |
Santos, Brian França dos Lemos Junior, Vilson de Lino, Juliana Ribeiro da Costa Leite, Cleber Queiroz |
author_role |
author |
author2 |
Lemos Junior, Vilson de Lino, Juliana Ribeiro da Costa Leite, Cleber Queiroz |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Santos, Brian França dos Lemos Junior, Vilson de Lino, Juliana Ribeiro da Costa Leite, Cleber Queiroz |
dc.subject.por.fl_str_mv |
Tumor del Estroma Gastrointestinal Proteína c-KIT Tracto Gastrointestinal Ultrasonido. Tumor Estromal Gastrointestinal Proteína c-KIT Trato Gastrointestinal Ecoendoscopia. Gastrointestinal Stromal Tumor C-KIT Protein Gastrointestinal Tract Endoscopy ultrasound. |
topic |
Tumor del Estroma Gastrointestinal Proteína c-KIT Tracto Gastrointestinal Ultrasonido. Tumor Estromal Gastrointestinal Proteína c-KIT Trato Gastrointestinal Ecoendoscopia. Gastrointestinal Stromal Tumor C-KIT Protein Gastrointestinal Tract Endoscopy ultrasound. |
description |
Gastrointestinal stromal tumors (GISTs) are generally quite rare, but the same are the mesenchymal neoplasms that are most frequently identified in the gastrointestinal tract (GIT) and represent 0.1 to 3% of all gastrointestinal tumors. The diagnosis of this pathology is made according to the clinical picture, in the morphological characteristics, and fundamentally in the consideration of the presence of the protein c-KIT (CD117) detected by immunohistochemical method. In most cases, these tumors present in the individual asymptomatically, so they are discovered incidentally by imaging exams. The prognostic factors of great importance are the size of the tumor and the mitotic index. Surgical resection is the therapy of choice and imatinib mesylate chemotherapy, which is indicated in cases of unresectability or metastatic disease. We present a case of Duodenal GIST diagnoses by echoendoscopy after an incidental finding during an upper gastrointestinal endoscopy exam. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-08-25 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/19407 10.33448/rsd-v10i11.19407 |
url |
https://rsdjournal.org/index.php/rsd/article/view/19407 |
identifier_str_mv |
10.33448/rsd-v10i11.19407 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/19407/17415 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 11; e124101119407 Research, Society and Development; Vol. 10 Núm. 11; e124101119407 Research, Society and Development; v. 10 n. 11; e124101119407 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
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1797052687592718336 |