Risk of respiratory depression at use of nitrous oxide on individuals with cerebral palsy: a clinical trial
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Research, Society and Development |
Texto Completo: | https://rsdjournal.org/index.php/rsd/article/view/20774 |
Resumo: | The dental care for individuals with cerebral palsy (CP) often result in the referral of patients for general anesthesia. Conscious sedation with nitrous oxide (N2O) could be an alternative resource, from a behavioral and physiological point of view, and could favor dental care in an outpatient setting. This study aimed to evaluate the influence of conscious sedation with N2O on respiratory rate (RR) and oxygen saturation (SpO2) in the dental treatment of individuals with CP. Seventy-seven patients with CP, over 3 years old, regardless of gender and ethnicity, were evaluated with the measurement of N2O titration, RR and SpO2 in four moments: initial, 5 minutes after sedation, 10 minutes after anesthesia and 5 minutes after removal of the N2O. Student's t test and ANOVA F were used, with a significance level of 5%. The variation in N2O titration did not generate significant variation in RR (p = 0.122). There was a significant difference in SpO2 between T1 and other times. It can be said that conscious sedation is not influenced by N2O titration, does not cause respiratory depression or any clinically significant change in SpO2, confirming the safety of use in an outpatient setting. |
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Risk of respiratory depression at use of nitrous oxide on individuals with cerebral palsy: a clinical trial Riesgo de depresión respiratoria por el uso de óxido nitroso en personas con parálisis cerebral: ensayo clínicoRisco de depressão respiratória no uso de óxido nitroso em indivíduos com paralisia cerebral: um ensaio clínicoCerebral palsyDental careConscious sedationNitrous oxide.Parálisis cerebralCuidado dentalSedación conscienteÓxido nitroso.Paralisia cerebralAssistência odontológicaSedação conscienteÓxido nitroso.The dental care for individuals with cerebral palsy (CP) often result in the referral of patients for general anesthesia. Conscious sedation with nitrous oxide (N2O) could be an alternative resource, from a behavioral and physiological point of view, and could favor dental care in an outpatient setting. This study aimed to evaluate the influence of conscious sedation with N2O on respiratory rate (RR) and oxygen saturation (SpO2) in the dental treatment of individuals with CP. Seventy-seven patients with CP, over 3 years old, regardless of gender and ethnicity, were evaluated with the measurement of N2O titration, RR and SpO2 in four moments: initial, 5 minutes after sedation, 10 minutes after anesthesia and 5 minutes after removal of the N2O. Student's t test and ANOVA F were used, with a significance level of 5%. The variation in N2O titration did not generate significant variation in RR (p = 0.122). There was a significant difference in SpO2 between T1 and other times. It can be said that conscious sedation is not influenced by N2O titration, does not cause respiratory depression or any clinically significant change in SpO2, confirming the safety of use in an outpatient setting.El cuidado dental para personas con parálisis cerebral (PC) a menudo resulta en la derivación de pacientes para anestesia general. La sedación consciente con óxido nitroso (N2O) puede ser un recurso alternativo, desde el punto de vista conductual y fisiológico, y puede favorecer la atención odontológica ambulatoria. Este estudio tuvo como objetivo evaluar la influencia de la sedación consciente con N2O sobre la frecuencia respiratoria (RR) y la saturación de oxígeno (SpO2) durante el tratamiento dental de personas con PC. Se evaluaron 77 pacientes con PC, mayores de 3 años, independientemente del sexo y la etnia, midiendo la titulación de N2O, RR y SpO2 en cuatro momentos: línea de base, 5 minutos después de la sedación, 10 minutos después de la anestesia y 5 minutos después de la eliminación del N2O. Se utilizó la prueba t de Student y ANOVA F, con un nivel de significancia del 5%. La variación en la titulación de N2O no generó una variación significativa en el RR (p = 0,122). Hubo una diferencia significativa en la SpO2 entre T1 y otros tiempos. Se puede decir que la sedación consciente no se ve influenciada por la titulación de N2O, no causa depresión respiratoria ni ningún cambio clínicamente significativo en la SpO2, lo que confirma la seguridad de su uso en un entorno ambulatorio.O atendimento odontológico a indivíduos com paralisia cerebral (PC) frequentemente resulta no encaminhamento de pacientes para anestesia geral. A sedação consciente com óxido nitroso (N2O) pode ser um recurso alternativo, do ponto de vista comportamental e fisiológico, e pode favorecer o atendimento odontológico ambulatorial. Este estudo teve como objetivo avaliar a influência da sedação consciente com N2O na frequência respiratória (FR) e saturação de oxigênio (SpO2) durante tratamento odontológico de indivíduos com PC. Setenta e sete pacientes com PC, maiores de 3 anos, independente de sexo e etnia, foram avaliados com a medida da titulação de N2O, FR e SpO2 em quatro momentos: inicial, 5 minutos após a sedação, 10 minutos após a anestesia e 5 minutos após a remoção do N2O. Foram utilizados o teste t de Student e ANOVA F, com nível de significância de 5%. A variação na titulação do N2O não gerou variação significativa na FR (p = 0,122). Houve diferença significativa na SpO2 entre T1 e outros momentos. Pode-se dizer que a sedação consciente não é influenciada pela titulação do N2O, não causa depressão respiratória ou qualquer alteração clinicamente significativa na SpO2, confirmando a segurança do uso em ambiente ambulatorial.Research, Society and Development2021-10-10info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://rsdjournal.org/index.php/rsd/article/view/2077410.33448/rsd-v10i13.20774Research, Society and Development; Vol. 10 No. 13; e198101320774Research, Society and Development; Vol. 10 Núm. 13; e198101320774Research, Society and Development; v. 10 n. 13; e1981013207742525-3409reponame:Research, Society and Developmentinstname:Universidade Federal de Itajubá (UNIFEI)instacron:UNIFEIenghttps://rsdjournal.org/index.php/rsd/article/view/20774/18805Copyright (c) 2021 Fernando Martins Baeder; Daniel Furtado Silva; Ana Carolina Lyra de Albuquerque; Dênis Clay Lopes dos Santos; Andrea Pavanello; Antônio Francisco David; Maria Teresa Botti Rodrigues Santoshttps://creativecommons.org/licenses/by/4.0info:eu-repo/semantics/openAccessBaeder, Fernando MartinsSilva, Daniel Furtado Albuquerque, Ana Carolina Lyra deSantos, Dênis Clay Lopes dos Pavanello, AndreaDavid, Antônio FranciscoSantos, Maria Teresa Botti Rodrigues 2021-11-21T18:26:28Zoai:ojs.pkp.sfu.ca:article/20774Revistahttps://rsdjournal.org/index.php/rsd/indexPUBhttps://rsdjournal.org/index.php/rsd/oairsd.articles@gmail.com2525-34092525-3409opendoar:2024-01-17T09:40:19.411208Research, Society and Development - Universidade Federal de Itajubá (UNIFEI)false |
dc.title.none.fl_str_mv |
Risk of respiratory depression at use of nitrous oxide on individuals with cerebral palsy: a clinical trial Riesgo de depresión respiratoria por el uso de óxido nitroso en personas con parálisis cerebral: ensayo clínico Risco de depressão respiratória no uso de óxido nitroso em indivíduos com paralisia cerebral: um ensaio clínico |
title |
Risk of respiratory depression at use of nitrous oxide on individuals with cerebral palsy: a clinical trial |
spellingShingle |
Risk of respiratory depression at use of nitrous oxide on individuals with cerebral palsy: a clinical trial Baeder, Fernando Martins Cerebral palsy Dental care Conscious sedation Nitrous oxide. Parálisis cerebral Cuidado dental Sedación consciente Óxido nitroso. Paralisia cerebral Assistência odontológica Sedação consciente Óxido nitroso. |
title_short |
Risk of respiratory depression at use of nitrous oxide on individuals with cerebral palsy: a clinical trial |
title_full |
Risk of respiratory depression at use of nitrous oxide on individuals with cerebral palsy: a clinical trial |
title_fullStr |
Risk of respiratory depression at use of nitrous oxide on individuals with cerebral palsy: a clinical trial |
title_full_unstemmed |
Risk of respiratory depression at use of nitrous oxide on individuals with cerebral palsy: a clinical trial |
title_sort |
Risk of respiratory depression at use of nitrous oxide on individuals with cerebral palsy: a clinical trial |
author |
Baeder, Fernando Martins |
author_facet |
Baeder, Fernando Martins Silva, Daniel Furtado Albuquerque, Ana Carolina Lyra de Santos, Dênis Clay Lopes dos Pavanello, Andrea David, Antônio Francisco Santos, Maria Teresa Botti Rodrigues |
author_role |
author |
author2 |
Silva, Daniel Furtado Albuquerque, Ana Carolina Lyra de Santos, Dênis Clay Lopes dos Pavanello, Andrea David, Antônio Francisco Santos, Maria Teresa Botti Rodrigues |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
Baeder, Fernando Martins Silva, Daniel Furtado Albuquerque, Ana Carolina Lyra de Santos, Dênis Clay Lopes dos Pavanello, Andrea David, Antônio Francisco Santos, Maria Teresa Botti Rodrigues |
dc.subject.por.fl_str_mv |
Cerebral palsy Dental care Conscious sedation Nitrous oxide. Parálisis cerebral Cuidado dental Sedación consciente Óxido nitroso. Paralisia cerebral Assistência odontológica Sedação consciente Óxido nitroso. |
topic |
Cerebral palsy Dental care Conscious sedation Nitrous oxide. Parálisis cerebral Cuidado dental Sedación consciente Óxido nitroso. Paralisia cerebral Assistência odontológica Sedação consciente Óxido nitroso. |
description |
The dental care for individuals with cerebral palsy (CP) often result in the referral of patients for general anesthesia. Conscious sedation with nitrous oxide (N2O) could be an alternative resource, from a behavioral and physiological point of view, and could favor dental care in an outpatient setting. This study aimed to evaluate the influence of conscious sedation with N2O on respiratory rate (RR) and oxygen saturation (SpO2) in the dental treatment of individuals with CP. Seventy-seven patients with CP, over 3 years old, regardless of gender and ethnicity, were evaluated with the measurement of N2O titration, RR and SpO2 in four moments: initial, 5 minutes after sedation, 10 minutes after anesthesia and 5 minutes after removal of the N2O. Student's t test and ANOVA F were used, with a significance level of 5%. The variation in N2O titration did not generate significant variation in RR (p = 0.122). There was a significant difference in SpO2 between T1 and other times. It can be said that conscious sedation is not influenced by N2O titration, does not cause respiratory depression or any clinically significant change in SpO2, confirming the safety of use in an outpatient setting. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-10-10 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/20774 10.33448/rsd-v10i13.20774 |
url |
https://rsdjournal.org/index.php/rsd/article/view/20774 |
identifier_str_mv |
10.33448/rsd-v10i13.20774 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://rsdjournal.org/index.php/rsd/article/view/20774/18805 |
dc.rights.driver.fl_str_mv |
https://creativecommons.org/licenses/by/4.0 info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
https://creativecommons.org/licenses/by/4.0 |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Research, Society and Development |
publisher.none.fl_str_mv |
Research, Society and Development |
dc.source.none.fl_str_mv |
Research, Society and Development; Vol. 10 No. 13; e198101320774 Research, Society and Development; Vol. 10 Núm. 13; e198101320774 Research, Society and Development; v. 10 n. 13; e198101320774 2525-3409 reponame:Research, Society and Development instname:Universidade Federal de Itajubá (UNIFEI) instacron:UNIFEI |
instname_str |
Universidade Federal de Itajubá (UNIFEI) |
instacron_str |
UNIFEI |
institution |
UNIFEI |
reponame_str |
Research, Society and Development |
collection |
Research, Society and Development |
repository.name.fl_str_mv |
Research, Society and Development - Universidade Federal de Itajubá (UNIFEI) |
repository.mail.fl_str_mv |
rsd.articles@gmail.com |
_version_ |
1797052691172556800 |