7-Hydroxycassine: A new 2,6-dialkylpiperidin-3-ol alkaloid and other constituents isolated from flowers and fruits of senna spectabilis (Fabaceae)

• Autor(a) principal: Viegas, Cláudio
• Data de Publicação: 2013
• Outros Autores: Pivatto, Marcos, De Rezende, Amanda [UNESP], Hamerski, Lidilhone [UNESP], Silva, Dulce Helena Siqueira [UNESP], Bolzani, Vanderlan da Silva [UNESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.5935/0103-5053.20130029; http://hdl.handle.net/11449/75053
• topic: (-)-7-hydroxycassine; Piperidine alkaloids; Senna spectabilis

The phytochemical study of flowers and green fruits of Senna spectabilis furnished a new substituted 2,6-dialkylpiperidin-3-ol alkaloid, named (-)-7-hydroxycassine, along with five known piperidine alkaloids: (-)-cassine, (-)-spectaline, (-)-3-O-acetylspectaline, (-)-7-hydroxyspectaline and (-)-iso-6-spectaline. In addition to non-alkaloidal, chemical constituents from other chemical classes were also identified, including the steroid β-sitosterol, the flavonoids luteolin and 3-methoxyluteolin, the triterpene betulinic acid and trans-cinnamic acid. To our knowledge, compounds are being reported for the first time in this species. © 2013 Sociedade Brasileira de Quimica.