Accuracy of differences in blood and peritoneal glucose to differentiate between septic and non-septic peritonitis in horses
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.rvsc.2020.06.017 http://hdl.handle.net/11449/200685 |
Resumo: | Difference in blood and peritoneal glucose (DBPG) is used in clinical practice to support a diagnosis of septic peritonitis in horses. It is inexpensive, easy and rapid to perform. The aim of this study was to evaluate the accuracy of the DBPG to differentiate between septic and non-septic peritonitis in horses. Blood and peritoneal fluids were harvested from suspected animals. Plasma and peritoneal glucose levels, total nucleated cell count, direct microscopic and microbiological examinations of the peritoneal fluid were evaluated. Using DBPG levels, the animals were classified into two groups: difference ≥ 50 mg/dL (positive test) and difference < 50 mg/dL (negative test). Positive microbiological examination and/or presence of bacteria in direct microscopic examination was used as a gold standard to detect septic peritonitis. The accuracy parameters analysed were: sensitivity, specificity, and positive/negative predictive values, for which the results were respectively: 0.23, 0.91, 0.60 and 0.67. Due to poor accuracy, other cut-off margins and peritoneal glucose concentrations were evaluated. The test was considered most accurate when the DBPG was zero with sensitivity, specificity, and positive/negative predictive values of 0.85, 0.82, 0.73, 0.90 respectively. Peritoneal glucose concentrations alone were not a reliable feature to detect peritonitis. DBPG ≥50 mg/dL, widely used for the diagnosis of septic peritonitis, does not have a good accuracy and the DBPG = 0 has a better accuracy for detecting the disease. |
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Accuracy of differences in blood and peritoneal glucose to differentiate between septic and non-septic peritonitis in horsesAbdominal infectionGlucose concentrationHorsesSeptic peritonitisSpecificityDifference in blood and peritoneal glucose (DBPG) is used in clinical practice to support a diagnosis of septic peritonitis in horses. It is inexpensive, easy and rapid to perform. The aim of this study was to evaluate the accuracy of the DBPG to differentiate between septic and non-septic peritonitis in horses. Blood and peritoneal fluids were harvested from suspected animals. Plasma and peritoneal glucose levels, total nucleated cell count, direct microscopic and microbiological examinations of the peritoneal fluid were evaluated. Using DBPG levels, the animals were classified into two groups: difference ≥ 50 mg/dL (positive test) and difference < 50 mg/dL (negative test). Positive microbiological examination and/or presence of bacteria in direct microscopic examination was used as a gold standard to detect septic peritonitis. The accuracy parameters analysed were: sensitivity, specificity, and positive/negative predictive values, for which the results were respectively: 0.23, 0.91, 0.60 and 0.67. Due to poor accuracy, other cut-off margins and peritoneal glucose concentrations were evaluated. The test was considered most accurate when the DBPG was zero with sensitivity, specificity, and positive/negative predictive values of 0.85, 0.82, 0.73, 0.90 respectively. Peritoneal glucose concentrations alone were not a reliable feature to detect peritonitis. DBPG ≥50 mg/dL, widely used for the diagnosis of septic peritonitis, does not have a good accuracy and the DBPG = 0 has a better accuracy for detecting the disease.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Department of Veterinary Surgery and Animal Reproduction School of Veterinary Medicine and Animal Science Univ. Estadual Paulista (Unesp)Department of Animal Production and Preventive Veterinary Medicine School of Veterinary Medicine and Animal Science Univ. Estadual Paulista (Unesp)Department of Internal Medicine Botucatu Medical School Univ. Estadual Paulista (Unesp)Department of Veterinary Clinics School of Veterinary Medicine and Animal Science Univ. Estadual Paulista (Unesp)Department of Veterinary Surgery and Animal Reproduction School of Veterinary Medicine and Animal Science Univ. Estadual Paulista (Unesp)Department of Animal Production and Preventive Veterinary Medicine School of Veterinary Medicine and Animal Science Univ. Estadual Paulista (Unesp)Department of Internal Medicine Botucatu Medical School Univ. Estadual Paulista (Unesp)Department of Veterinary Clinics School of Veterinary Medicine and Animal Science Univ. Estadual Paulista (Unesp)FAPESP: 2016/08712-8 e 2018/ 16013-8Universidade Estadual Paulista (Unesp)Alonso, Juliana de Moura [UNESP]Esper, Carolina Soares [UNESP]Pantoja, José Carlos Figueiredo [UNESP]Rosa, Gustavo dos Santos [UNESP]Giampietro, Rodrigo Rosa [UNESP]dos Santos, Bruna [UNESP]Guerra, Simony Trevizan [UNESP]Ribeiro, Márcio Garcia [UNESP]Takahira, Regina Kiomi [UNESP]Watanabe, Marcos Jun [UNESP]Alves, Ana Liz Garcia [UNESP]Rodrigues, Celso Antônio [UNESP]García, Henry David Mogollón [UNESP]Hussni, Carlos Alberto [UNESP]2020-12-12T02:13:21Z2020-12-12T02:13:21Z2020-10-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article237-242http://dx.doi.org/10.1016/j.rvsc.2020.06.017Research in Veterinary Science, v. 132, p. 237-242.1532-26610034-5288http://hdl.handle.net/11449/20068510.1016/j.rvsc.2020.06.0172-s2.0-85087306480Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengResearch in Veterinary Scienceinfo:eu-repo/semantics/openAccess2021-10-23T14:33:35Zoai:repositorio.unesp.br:11449/200685Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T14:33:35Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Accuracy of differences in blood and peritoneal glucose to differentiate between septic and non-septic peritonitis in horses |
title |
Accuracy of differences in blood and peritoneal glucose to differentiate between septic and non-septic peritonitis in horses |
spellingShingle |
Accuracy of differences in blood and peritoneal glucose to differentiate between septic and non-septic peritonitis in horses Alonso, Juliana de Moura [UNESP] Abdominal infection Glucose concentration Horses Septic peritonitis Specificity |
title_short |
Accuracy of differences in blood and peritoneal glucose to differentiate between septic and non-septic peritonitis in horses |
title_full |
Accuracy of differences in blood and peritoneal glucose to differentiate between septic and non-septic peritonitis in horses |
title_fullStr |
Accuracy of differences in blood and peritoneal glucose to differentiate between septic and non-septic peritonitis in horses |
title_full_unstemmed |
Accuracy of differences in blood and peritoneal glucose to differentiate between septic and non-septic peritonitis in horses |
title_sort |
Accuracy of differences in blood and peritoneal glucose to differentiate between septic and non-septic peritonitis in horses |
author |
Alonso, Juliana de Moura [UNESP] |
author_facet |
Alonso, Juliana de Moura [UNESP] Esper, Carolina Soares [UNESP] Pantoja, José Carlos Figueiredo [UNESP] Rosa, Gustavo dos Santos [UNESP] Giampietro, Rodrigo Rosa [UNESP] dos Santos, Bruna [UNESP] Guerra, Simony Trevizan [UNESP] Ribeiro, Márcio Garcia [UNESP] Takahira, Regina Kiomi [UNESP] Watanabe, Marcos Jun [UNESP] Alves, Ana Liz Garcia [UNESP] Rodrigues, Celso Antônio [UNESP] García, Henry David Mogollón [UNESP] Hussni, Carlos Alberto [UNESP] |
author_role |
author |
author2 |
Esper, Carolina Soares [UNESP] Pantoja, José Carlos Figueiredo [UNESP] Rosa, Gustavo dos Santos [UNESP] Giampietro, Rodrigo Rosa [UNESP] dos Santos, Bruna [UNESP] Guerra, Simony Trevizan [UNESP] Ribeiro, Márcio Garcia [UNESP] Takahira, Regina Kiomi [UNESP] Watanabe, Marcos Jun [UNESP] Alves, Ana Liz Garcia [UNESP] Rodrigues, Celso Antônio [UNESP] García, Henry David Mogollón [UNESP] Hussni, Carlos Alberto [UNESP] |
author2_role |
author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Alonso, Juliana de Moura [UNESP] Esper, Carolina Soares [UNESP] Pantoja, José Carlos Figueiredo [UNESP] Rosa, Gustavo dos Santos [UNESP] Giampietro, Rodrigo Rosa [UNESP] dos Santos, Bruna [UNESP] Guerra, Simony Trevizan [UNESP] Ribeiro, Márcio Garcia [UNESP] Takahira, Regina Kiomi [UNESP] Watanabe, Marcos Jun [UNESP] Alves, Ana Liz Garcia [UNESP] Rodrigues, Celso Antônio [UNESP] García, Henry David Mogollón [UNESP] Hussni, Carlos Alberto [UNESP] |
dc.subject.por.fl_str_mv |
Abdominal infection Glucose concentration Horses Septic peritonitis Specificity |
topic |
Abdominal infection Glucose concentration Horses Septic peritonitis Specificity |
description |
Difference in blood and peritoneal glucose (DBPG) is used in clinical practice to support a diagnosis of septic peritonitis in horses. It is inexpensive, easy and rapid to perform. The aim of this study was to evaluate the accuracy of the DBPG to differentiate between septic and non-septic peritonitis in horses. Blood and peritoneal fluids were harvested from suspected animals. Plasma and peritoneal glucose levels, total nucleated cell count, direct microscopic and microbiological examinations of the peritoneal fluid were evaluated. Using DBPG levels, the animals were classified into two groups: difference ≥ 50 mg/dL (positive test) and difference < 50 mg/dL (negative test). Positive microbiological examination and/or presence of bacteria in direct microscopic examination was used as a gold standard to detect septic peritonitis. The accuracy parameters analysed were: sensitivity, specificity, and positive/negative predictive values, for which the results were respectively: 0.23, 0.91, 0.60 and 0.67. Due to poor accuracy, other cut-off margins and peritoneal glucose concentrations were evaluated. The test was considered most accurate when the DBPG was zero with sensitivity, specificity, and positive/negative predictive values of 0.85, 0.82, 0.73, 0.90 respectively. Peritoneal glucose concentrations alone were not a reliable feature to detect peritonitis. DBPG ≥50 mg/dL, widely used for the diagnosis of septic peritonitis, does not have a good accuracy and the DBPG = 0 has a better accuracy for detecting the disease. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-12T02:13:21Z 2020-12-12T02:13:21Z 2020-10-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.rvsc.2020.06.017 Research in Veterinary Science, v. 132, p. 237-242. 1532-2661 0034-5288 http://hdl.handle.net/11449/200685 10.1016/j.rvsc.2020.06.017 2-s2.0-85087306480 |
url |
http://dx.doi.org/10.1016/j.rvsc.2020.06.017 http://hdl.handle.net/11449/200685 |
identifier_str_mv |
Research in Veterinary Science, v. 132, p. 237-242. 1532-2661 0034-5288 10.1016/j.rvsc.2020.06.017 2-s2.0-85087306480 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Research in Veterinary Science |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
237-242 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1797790024797782016 |