Fatores preditivos para a ocorrência de pólipos endometriais em mulheres na pós-menopausa
Autor(a) principal: | |
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Data de Publicação: | 2014 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S0100-720320140005090 http://hdl.handle.net/11449/140863 |
Resumo: | PURPOSE: To evaluate the predictive clinical factors for the development of endometrial polyps in postmenopausal women. METHODS: Observational cohort study with postmenopausal women who had been at a public university hospital. Clinical, anthropometrical, laboratorial, and ultrasonographic data of 132 patients with a histopathological diagnosis of endometrial polyps and 264 women without endometrial alterations (control) were compared in order to evaluate the predictive factors of endometrial polyps. Women with amenorrhea ≥12 months and ≥45 years of age were included in the study at a proportion of 1 case for 2 controls. The Student’s t-, χ2, and logistic regression tests were used for statistical analysis – odds ratio (OR). RESULTS: Patients with endometrial polyps were older and had been in menopause for a longer time compared to control (p<0.0001). The percentage of obese women with polyps (72.0%) was higher compared to the Control Group (39%; p<0.0001). The measurement of waist circumference was superior among patients with polyps (p=0.0001). We observed a higher incidence of diabetes, hypertension and dyslipidemia in patients with endometrial polyps (p<0.0001). According to the US National Cholesterol Education Program/Adult Treatment Panel III (NCEP/ATP III) criteria, 48.5% of women with polyps and 33.3% of the Control Group were classified as having metabolic syndrome (p=0.004). Analysis of risk for endometrial polyps formation showed higher chances of occurrence of the disorder in patients with: BMI≥25 kg/m² (OR=4.6; 95%CI 2.1–10.0); glucose ≥100 mg/dL (OR=2.8; 95%CI 1.3–5.9); dyslipidemia (OR=7.0; 95%CI 3.7–13.3); diabetes (OR=2.5; 95%CI 1.0–6.3), and metabolic syndrome (OR=2.7; 95%CI 1.1–6.4) compared to the Control Group. CONCLUSION: In postmenopausal women, obesity, dyslipidemia, hyperglycemia and presence of metabolic syndrome were predictive factors for the development of endometrial polyps. |
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Fatores preditivos para a ocorrência de pólipos endometriais em mulheres na pós-menopausaPredictive factors for occurrence of endometrial polyps in postmenopausal womenEndometriumRisk factorsMenopausePolypsMetabolic syndrome XEndométrioFatores de riscoMenopausaPóliposSíndrome X metabólicaPURPOSE: To evaluate the predictive clinical factors for the development of endometrial polyps in postmenopausal women. METHODS: Observational cohort study with postmenopausal women who had been at a public university hospital. Clinical, anthropometrical, laboratorial, and ultrasonographic data of 132 patients with a histopathological diagnosis of endometrial polyps and 264 women without endometrial alterations (control) were compared in order to evaluate the predictive factors of endometrial polyps. Women with amenorrhea ≥12 months and ≥45 years of age were included in the study at a proportion of 1 case for 2 controls. The Student’s t-, χ2, and logistic regression tests were used for statistical analysis – odds ratio (OR). RESULTS: Patients with endometrial polyps were older and had been in menopause for a longer time compared to control (p<0.0001). The percentage of obese women with polyps (72.0%) was higher compared to the Control Group (39%; p<0.0001). The measurement of waist circumference was superior among patients with polyps (p=0.0001). We observed a higher incidence of diabetes, hypertension and dyslipidemia in patients with endometrial polyps (p<0.0001). According to the US National Cholesterol Education Program/Adult Treatment Panel III (NCEP/ATP III) criteria, 48.5% of women with polyps and 33.3% of the Control Group were classified as having metabolic syndrome (p=0.004). Analysis of risk for endometrial polyps formation showed higher chances of occurrence of the disorder in patients with: BMI≥25 kg/m² (OR=4.6; 95%CI 2.1–10.0); glucose ≥100 mg/dL (OR=2.8; 95%CI 1.3–5.9); dyslipidemia (OR=7.0; 95%CI 3.7–13.3); diabetes (OR=2.5; 95%CI 1.0–6.3), and metabolic syndrome (OR=2.7; 95%CI 1.1–6.4) compared to the Control Group. CONCLUSION: In postmenopausal women, obesity, dyslipidemia, hyperglycemia and presence of metabolic syndrome were predictive factors for the development of endometrial polyps.OBJETIVO: Avaliar os fatores clínicos preditivos para o desenvolvimento dos pólipos endometriais em mulheres na pós-menopausa. MÉTODOS: Estudo de coorte observacional com mulheres na pós-menopausa, que haviam sido atendidas em hospital público universitário. Dados clínicos, antropométricos, laboratoriais e ultrassonográficos de 132 pacientes com diagnóstico anatomopatológico de pólipo endometrial e de 264 mulheres sem alterações endometriais (controle) foram comparados para avaliar os fatores preditivos do pólipo endometrial. Foram incluídas no estudo mulheres com amenorreia ≥12 meses e idade ≥45 anos, em uma proporção de 1 caso para 2 controles. Para a análise estatística, foram empregados os testes t de Student, χ2 e regressão logística — odds ratio (OR). RESULTADOS: As pacientes com pólipo endometrial apresentaram idade mais avançada e maior tempo de menopausa quando comparadas ao controle (p<0,0001). A porcentagem de mulheres obesas com pólipo (72,0%) foi superior à do Grupo Controle (39%; p<0,0001). A medida da circunferência da cintura foi superior entre as pacientes com pólipo (p=0,0001). Observou-se uma incidência de diabetes, hipertensão e dislipidemias mais elevada nas pacientes com pólipo endometrial (p<0,0001). De acordo com os critérios do US National Cholesterol Education Program/ Adult Treatment Panel III (NCEP/ATP III), 48,5% das mulheres com pólipo e 33,3% do Grupo Controle foram classificadas como portadoras de síndrome metabólica (p=0,004). Em relação ao Grupo Controle, apresentaram maior chance de desenvolvimento de pólipo endometrial as pacientes com: IMC≥25 kg/m2 (OR=4,6; IC95% 2,1–10,0); glicose ≥100 mg/dL (OR=2,8; IC95% 1,3–5,9); dislipidemia (OR=7,0; IC95% 3,7–13,3); diabetes (OR=2,5; IC95% 1,0–6,3) e síndrome metabólica (OR=2,7; IC95% 1,1–6,4). CONCLUSÃO: Em mulheres na pós-menopausa, obesidade, dislipidemia, hiperglicemia e presença de síndrome metabólica foram fatores preditivos para o desenvolvimento de pólipo endometrial.Universidade Estadual Paulista Julio de Mesquita Filho (UNESP), Faculdade de Medicina de Botucatu (FMB), Departamento de Ginecologia e Obstetrícia, Botucatu, SP, BrasilUniversidade Estadual Paulista Julio de Mesquita Filho (UNESP), Faculdade de Medicina de Botucatu (FMB), Departamento de Ginecologia e Obstetrícia, Botucatu, SP, BrasilUniversidade Estadual Paulista (Unesp)Dias, Flávia Neves Bueloni [UNESP]Dias, Daniel Spadoto [UNESP]Nahás Neto, Jorge [UNESP]Nahás, Eliana Aguiar Petri [UNESP]2016-07-07T12:35:45Z2016-07-07T12:35:45Z2014info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article489-496application/pdfhttp://dx.doi.org/10.1590/S0100-720320140005090Revista Brasileira de Ginecologia e Obstetrícia, v. 36, n. 11, p. 489-496, 2014.0100-7203http://hdl.handle.net/11449/14086310.1590/S0100-720320140005090S0100-72032014001100489S0100-72032014001100489.pdf415517057478841741551705747884174155170574788417Currículo Lattesreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporRevista Brasileira de Ginecologia e Obstetrícia0,292info:eu-repo/semantics/openAccess2023-11-07T06:07:23Zoai:repositorio.unesp.br:11449/140863Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-11-07T06:07:23Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Fatores preditivos para a ocorrência de pólipos endometriais em mulheres na pós-menopausa Predictive factors for occurrence of endometrial polyps in postmenopausal women |
title |
Fatores preditivos para a ocorrência de pólipos endometriais em mulheres na pós-menopausa |
spellingShingle |
Fatores preditivos para a ocorrência de pólipos endometriais em mulheres na pós-menopausa Dias, Flávia Neves Bueloni [UNESP] Endometrium Risk factors Menopause Polyps Metabolic syndrome X Endométrio Fatores de risco Menopausa Pólipos Síndrome X metabólica |
title_short |
Fatores preditivos para a ocorrência de pólipos endometriais em mulheres na pós-menopausa |
title_full |
Fatores preditivos para a ocorrência de pólipos endometriais em mulheres na pós-menopausa |
title_fullStr |
Fatores preditivos para a ocorrência de pólipos endometriais em mulheres na pós-menopausa |
title_full_unstemmed |
Fatores preditivos para a ocorrência de pólipos endometriais em mulheres na pós-menopausa |
title_sort |
Fatores preditivos para a ocorrência de pólipos endometriais em mulheres na pós-menopausa |
author |
Dias, Flávia Neves Bueloni [UNESP] |
author_facet |
Dias, Flávia Neves Bueloni [UNESP] Dias, Daniel Spadoto [UNESP] Nahás Neto, Jorge [UNESP] Nahás, Eliana Aguiar Petri [UNESP] |
author_role |
author |
author2 |
Dias, Daniel Spadoto [UNESP] Nahás Neto, Jorge [UNESP] Nahás, Eliana Aguiar Petri [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Dias, Flávia Neves Bueloni [UNESP] Dias, Daniel Spadoto [UNESP] Nahás Neto, Jorge [UNESP] Nahás, Eliana Aguiar Petri [UNESP] |
dc.subject.por.fl_str_mv |
Endometrium Risk factors Menopause Polyps Metabolic syndrome X Endométrio Fatores de risco Menopausa Pólipos Síndrome X metabólica |
topic |
Endometrium Risk factors Menopause Polyps Metabolic syndrome X Endométrio Fatores de risco Menopausa Pólipos Síndrome X metabólica |
description |
PURPOSE: To evaluate the predictive clinical factors for the development of endometrial polyps in postmenopausal women. METHODS: Observational cohort study with postmenopausal women who had been at a public university hospital. Clinical, anthropometrical, laboratorial, and ultrasonographic data of 132 patients with a histopathological diagnosis of endometrial polyps and 264 women without endometrial alterations (control) were compared in order to evaluate the predictive factors of endometrial polyps. Women with amenorrhea ≥12 months and ≥45 years of age were included in the study at a proportion of 1 case for 2 controls. The Student’s t-, χ2, and logistic regression tests were used for statistical analysis – odds ratio (OR). RESULTS: Patients with endometrial polyps were older and had been in menopause for a longer time compared to control (p<0.0001). The percentage of obese women with polyps (72.0%) was higher compared to the Control Group (39%; p<0.0001). The measurement of waist circumference was superior among patients with polyps (p=0.0001). We observed a higher incidence of diabetes, hypertension and dyslipidemia in patients with endometrial polyps (p<0.0001). According to the US National Cholesterol Education Program/Adult Treatment Panel III (NCEP/ATP III) criteria, 48.5% of women with polyps and 33.3% of the Control Group were classified as having metabolic syndrome (p=0.004). Analysis of risk for endometrial polyps formation showed higher chances of occurrence of the disorder in patients with: BMI≥25 kg/m² (OR=4.6; 95%CI 2.1–10.0); glucose ≥100 mg/dL (OR=2.8; 95%CI 1.3–5.9); dyslipidemia (OR=7.0; 95%CI 3.7–13.3); diabetes (OR=2.5; 95%CI 1.0–6.3), and metabolic syndrome (OR=2.7; 95%CI 1.1–6.4) compared to the Control Group. CONCLUSION: In postmenopausal women, obesity, dyslipidemia, hyperglycemia and presence of metabolic syndrome were predictive factors for the development of endometrial polyps. |
publishDate |
2014 |
dc.date.none.fl_str_mv |
2014 2016-07-07T12:35:45Z 2016-07-07T12:35:45Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0100-720320140005090 Revista Brasileira de Ginecologia e Obstetrícia, v. 36, n. 11, p. 489-496, 2014. 0100-7203 http://hdl.handle.net/11449/140863 10.1590/S0100-720320140005090 S0100-72032014001100489 S0100-72032014001100489.pdf 4155170574788417 4155170574788417 4155170574788417 |
url |
http://dx.doi.org/10.1590/S0100-720320140005090 http://hdl.handle.net/11449/140863 |
identifier_str_mv |
Revista Brasileira de Ginecologia e Obstetrícia, v. 36, n. 11, p. 489-496, 2014. 0100-7203 10.1590/S0100-720320140005090 S0100-72032014001100489 S0100-72032014001100489.pdf 4155170574788417 |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Revista Brasileira de Ginecologia e Obstetrícia 0,292 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
489-496 application/pdf |
dc.source.none.fl_str_mv |
Currículo Lattes reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1799964844478169088 |