Histological study of hamster buccal mucosa following topical application of DMBA and exposition to low power 337 nm laser light
Main Author: | |
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Publication Date: | 2003 |
Other Authors: | , , , , , , , |
Format: | Conference object |
Language: | eng |
Source: | Repositório Institucional da UNESP |
Download full: | http://dx.doi.org/10.1117/12.474125 http://hdl.handle.net/11449/67416 |
Summary: | The aim of the present work is to analyze the histological changes on hamster buccal mucosa caused by the topical use of 7,12-dimethylbenzanthracene (DMBA) and exposition to a 220 μJ/pulse nitrogen laser light (@ 337 nm) at an average power of 2,3 mW. Twenty-one hamsters divided into two experimental groups were treated six times with DMBA. One hamster was kept as control. Group I was composed by ten hamsters and was submitted only to DMBA. Group II, also with ten hamsters, received the same treatment as group I and was exposed to the laser radiation. The time duration of each irradiation section was 10 seconds. All the treatment happened in alternated days. The histological analysis took place twice, after the end of the treatment and after sixty days. Both experimental groups presented dilatation of vessels, thickening of the epithelial tissue and the presence of inflammatory infiltrates. The preliminary results indicates that in group II the number of dilated vessels and its new area are much more significant than in group I. |
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Histological study of hamster buccal mucosa following topical application of DMBA and exposition to low power 337 nm laser lightCarcinogenesisDMBAMutagenesisUV laserCarcinogensIrradiationLasersUltraviolet radiationHamster buccal mucosaHistologyThe aim of the present work is to analyze the histological changes on hamster buccal mucosa caused by the topical use of 7,12-dimethylbenzanthracene (DMBA) and exposition to a 220 μJ/pulse nitrogen laser light (@ 337 nm) at an average power of 2,3 mW. Twenty-one hamsters divided into two experimental groups were treated six times with DMBA. One hamster was kept as control. Group I was composed by ten hamsters and was submitted only to DMBA. Group II, also with ten hamsters, received the same treatment as group I and was exposed to the laser radiation. The time duration of each irradiation section was 10 seconds. All the treatment happened in alternated days. The histological analysis took place twice, after the end of the treatment and after sixty days. Both experimental groups presented dilatation of vessels, thickening of the epithelial tissue and the presence of inflammatory infiltrates. The preliminary results indicates that in group II the number of dilated vessels and its new area are much more significant than in group I.Inst. de Pesquisa e Desenvolvimento Univap, São José dos CamposFaculdade de Odontologia Unesp, São Josê dos CamposFaculdade de Odontologia Univap, São José dos CamposFaculdade de Odontologia Unesp, São Josê dos CamposUnivapUniversidade Estadual Paulista (Unesp)De Barros Rego, C. M VMunin, E.Redígolo, M. L.Salgado, M. C. [UNESP]De Souza, H. P.Colombo, C. E DNicolau, R. A.Alves, L. P.Zângaro, R. A.2014-05-27T11:20:54Z2014-05-27T11:20:54Z2003-09-29info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObject181-185http://dx.doi.org/10.1117/12.474125Proceedings of SPIE - The International Society for Optical Engineering, v. 4952, p. 181-185.0277-786Xhttp://hdl.handle.net/11449/6741610.1117/12.4741252-s2.0-0141828959Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengProceedings of SPIE - The International Society for Optical Engineeringinfo:eu-repo/semantics/openAccess2021-10-23T21:41:26Zoai:repositorio.unesp.br:11449/67416Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T21:41:26Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Histological study of hamster buccal mucosa following topical application of DMBA and exposition to low power 337 nm laser light |
title |
Histological study of hamster buccal mucosa following topical application of DMBA and exposition to low power 337 nm laser light |
spellingShingle |
Histological study of hamster buccal mucosa following topical application of DMBA and exposition to low power 337 nm laser light De Barros Rego, C. M V Carcinogenesis DMBA Mutagenesis UV laser Carcinogens Irradiation Lasers Ultraviolet radiation Hamster buccal mucosa Histology |
title_short |
Histological study of hamster buccal mucosa following topical application of DMBA and exposition to low power 337 nm laser light |
title_full |
Histological study of hamster buccal mucosa following topical application of DMBA and exposition to low power 337 nm laser light |
title_fullStr |
Histological study of hamster buccal mucosa following topical application of DMBA and exposition to low power 337 nm laser light |
title_full_unstemmed |
Histological study of hamster buccal mucosa following topical application of DMBA and exposition to low power 337 nm laser light |
title_sort |
Histological study of hamster buccal mucosa following topical application of DMBA and exposition to low power 337 nm laser light |
author |
De Barros Rego, C. M V |
author_facet |
De Barros Rego, C. M V Munin, E. Redígolo, M. L. Salgado, M. C. [UNESP] De Souza, H. P. Colombo, C. E D Nicolau, R. A. Alves, L. P. Zângaro, R. A. |
author_role |
author |
author2 |
Munin, E. Redígolo, M. L. Salgado, M. C. [UNESP] De Souza, H. P. Colombo, C. E D Nicolau, R. A. Alves, L. P. Zângaro, R. A. |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Univap Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
De Barros Rego, C. M V Munin, E. Redígolo, M. L. Salgado, M. C. [UNESP] De Souza, H. P. Colombo, C. E D Nicolau, R. A. Alves, L. P. Zângaro, R. A. |
dc.subject.por.fl_str_mv |
Carcinogenesis DMBA Mutagenesis UV laser Carcinogens Irradiation Lasers Ultraviolet radiation Hamster buccal mucosa Histology |
topic |
Carcinogenesis DMBA Mutagenesis UV laser Carcinogens Irradiation Lasers Ultraviolet radiation Hamster buccal mucosa Histology |
description |
The aim of the present work is to analyze the histological changes on hamster buccal mucosa caused by the topical use of 7,12-dimethylbenzanthracene (DMBA) and exposition to a 220 μJ/pulse nitrogen laser light (@ 337 nm) at an average power of 2,3 mW. Twenty-one hamsters divided into two experimental groups were treated six times with DMBA. One hamster was kept as control. Group I was composed by ten hamsters and was submitted only to DMBA. Group II, also with ten hamsters, received the same treatment as group I and was exposed to the laser radiation. The time duration of each irradiation section was 10 seconds. All the treatment happened in alternated days. The histological analysis took place twice, after the end of the treatment and after sixty days. Both experimental groups presented dilatation of vessels, thickening of the epithelial tissue and the presence of inflammatory infiltrates. The preliminary results indicates that in group II the number of dilated vessels and its new area are much more significant than in group I. |
publishDate |
2003 |
dc.date.none.fl_str_mv |
2003-09-29 2014-05-27T11:20:54Z 2014-05-27T11:20:54Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/conferenceObject |
format |
conferenceObject |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1117/12.474125 Proceedings of SPIE - The International Society for Optical Engineering, v. 4952, p. 181-185. 0277-786X http://hdl.handle.net/11449/67416 10.1117/12.474125 2-s2.0-0141828959 |
url |
http://dx.doi.org/10.1117/12.474125 http://hdl.handle.net/11449/67416 |
identifier_str_mv |
Proceedings of SPIE - The International Society for Optical Engineering, v. 4952, p. 181-185. 0277-786X 10.1117/12.474125 2-s2.0-0141828959 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Proceedings of SPIE - The International Society for Optical Engineering |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
181-185 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1797789616010428416 |