Anticariogenic potencial of acidulate solutions with low fluoride concentration

Detalhes bibliográficos
Autor(a) principal: Delbem, Alberto Carlos Botazzo [UNESP]
Data de Publicação: 2006
Outros Autores: Tiano, Gilberto Carlos [UNESP], Alves, Karina Mirela Riheiro Pinto [UNESP], Cunha, Robson Frederico [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S1678-77572006000400004
http://hdl.handle.net/11449/154119
Resumo: Objetives: The aim of this study was to verify the anticariogenic effect of acidulate solutions with low NaF concentration, using pH-cycling model and bovine enamel. Material and methods: Enamel blocks were submitted to the surface microhardness (SMH) test and randomly divided in 12 experimental and one placebo groups. The blocks were submitted to pH cycling for 7 days, with daily applications once/day of 0.05% NaF and 0.1% NaF and twice/day of 0.02% NaF solutions. Four different pH: 4.0. 5.0, 6.0 and 7.0 were used. Next, SMH test was again used to determine the surface microhardness percentage change (%SMH). Data obtained for %SMH were homogeneous and passed through variance analyses and Tukey's test (5%) as far as fluoride concentrations and pH. Resulls:The results showed that pH influenced %SMH in 0.02% NaF and 0.05% NaF solutions with pH 4.0, which had less mineral loss compared to pH 7.0 (p̃0.05). The 0.02% NaF - pH 4.0, and 0.05% NaF- pH 7.0 groups showed similar results (p>0.05). A dose-response relationship was observed among the tested solutions, with better anticariogenic effect for the 0.1% NaF solution. Conclusion: The results suggest that the addition of citric acid to acidulate mouth rinses reduce mineral loss.
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spelling Anticariogenic potencial of acidulate solutions with low fluoride concentrationPotencial anticariogênico de soluções aciduladas com baixa concentração de flúorAdministration & dosageDental cariesDental enamelHardnessPrevention & controlSodium fluorideObjetives: The aim of this study was to verify the anticariogenic effect of acidulate solutions with low NaF concentration, using pH-cycling model and bovine enamel. Material and methods: Enamel blocks were submitted to the surface microhardness (SMH) test and randomly divided in 12 experimental and one placebo groups. The blocks were submitted to pH cycling for 7 days, with daily applications once/day of 0.05% NaF and 0.1% NaF and twice/day of 0.02% NaF solutions. Four different pH: 4.0. 5.0, 6.0 and 7.0 were used. Next, SMH test was again used to determine the surface microhardness percentage change (%SMH). Data obtained for %SMH were homogeneous and passed through variance analyses and Tukey's test (5%) as far as fluoride concentrations and pH. Resulls:The results showed that pH influenced %SMH in 0.02% NaF and 0.05% NaF solutions with pH 4.0, which had less mineral loss compared to pH 7.0 (p̃0.05). The 0.02% NaF - pH 4.0, and 0.05% NaF- pH 7.0 groups showed similar results (p>0.05). A dose-response relationship was observed among the tested solutions, with better anticariogenic effect for the 0.1% NaF solution. Conclusion: The results suggest that the addition of citric acid to acidulate mouth rinses reduce mineral loss.Objetivo: O objetivo do presente estudo foi verificar o efeito anticariogênico de soluções aciduladas com baixa concentração de flúor, usando um modelo de ciclagem de pH e esmalte bovino. Máterial e Método: Blocos de esmalte foram polidos, submetidos ao teste de microdureza de superfície (SMH) e divididos aleatoriamente em 12 grupos experimentais e um placebo. Os blocos foram submetidos à ciclagem de pH por 7 dias e a aplicações diárias de soluções de NaF a 0,05% e 0,1% (1x) e de 0,02% (2x), com pHs 4.0, 5.0, 6.0 e 7.0. A seguir, determinou-se a SMH novamente para o cálculo da porcentagem de alteração da microdureza de superfície (%SMH). Os dados de %SMH foram homogêneos e submetidos a análise de variância e teste de Tukey (5%) considerando as concentrações de flúor e pH. Resultados: O pH influenciou a %SMH nas soluções de NaF 0,02% e 0,05% com pH 4.0, no qual a perda mineral foi menor quando comparado ao pH 7.0 (p<0,05). Os grupos das soluções de NaF 0,02% - pH 4.0, e de NaF 0,05% - pH 7.0 mostraram resultados similares (p>0,05). A relação dose-resposta foi observada entre as soluções testadas, com melhor efeito anticariogênico para a solução de NaF 0,1%. Conclusão: Os resultados sugerem que a acidificação das soluções com baixa concentração de fluoreto reduz a perda mineral.UNSEP-São Paulo State University School of Dentistry of Araçatuba Department of Pediatric Dentistry, SPR. José Bonifácio, 1193, Araçatuba, SP - Cep.: 16015-050UNESP – São Paulo State University, School of Dentistry of Araçatuba - Department of Pediatric Dentistry, SP, Brazil.Journal Of Applied Oral Science : Revista FobUniversidade Estadual Paulista (Unesp)Delbem, Alberto Carlos Botazzo [UNESP]Tiano, Gilberto Carlos [UNESP]Alves, Karina Mirela Riheiro Pinto [UNESP]Cunha, Robson Frederico [UNESP]2014-05-27T11:22:04Z2015-12-07T15:29:50Z2014-05-27T11:22:04Z2015-12-07T15:29:50Z2006-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article233-237application/pdfhttp://dx.doi.org/10.1590/S1678-77572006000400004Journal of Applied Oral Science, v. 14, n. 4, p. 233-237, 2006.1678-77571678-7765http://hdl.handle.net/11449/15411910.1590/S1678-77572006000400004S1678-775720060004000042-s2.0-482490962482-s2.0-48249096248.pdf684435414991795719089268PMC43274780000-0002-8159-4853ScopusPubMedreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Applied Oral Science1.7090,645info:eu-repo/semantics/openAccess2023-12-22T06:19:11Zoai:repositorio.unesp.br:11449/154119Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-12-22T06:19:11Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Anticariogenic potencial of acidulate solutions with low fluoride concentration
Potencial anticariogênico de soluções aciduladas com baixa concentração de flúor
title Anticariogenic potencial of acidulate solutions with low fluoride concentration
spellingShingle Anticariogenic potencial of acidulate solutions with low fluoride concentration
Delbem, Alberto Carlos Botazzo [UNESP]
Administration & dosage
Dental caries
Dental enamel
Hardness
Prevention & control
Sodium fluoride
title_short Anticariogenic potencial of acidulate solutions with low fluoride concentration
title_full Anticariogenic potencial of acidulate solutions with low fluoride concentration
title_fullStr Anticariogenic potencial of acidulate solutions with low fluoride concentration
title_full_unstemmed Anticariogenic potencial of acidulate solutions with low fluoride concentration
title_sort Anticariogenic potencial of acidulate solutions with low fluoride concentration
author Delbem, Alberto Carlos Botazzo [UNESP]
author_facet Delbem, Alberto Carlos Botazzo [UNESP]
Tiano, Gilberto Carlos [UNESP]
Alves, Karina Mirela Riheiro Pinto [UNESP]
Cunha, Robson Frederico [UNESP]
author_role author
author2 Tiano, Gilberto Carlos [UNESP]
Alves, Karina Mirela Riheiro Pinto [UNESP]
Cunha, Robson Frederico [UNESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Delbem, Alberto Carlos Botazzo [UNESP]
Tiano, Gilberto Carlos [UNESP]
Alves, Karina Mirela Riheiro Pinto [UNESP]
Cunha, Robson Frederico [UNESP]
dc.subject.por.fl_str_mv Administration & dosage
Dental caries
Dental enamel
Hardness
Prevention & control
Sodium fluoride
topic Administration & dosage
Dental caries
Dental enamel
Hardness
Prevention & control
Sodium fluoride
description Objetives: The aim of this study was to verify the anticariogenic effect of acidulate solutions with low NaF concentration, using pH-cycling model and bovine enamel. Material and methods: Enamel blocks were submitted to the surface microhardness (SMH) test and randomly divided in 12 experimental and one placebo groups. The blocks were submitted to pH cycling for 7 days, with daily applications once/day of 0.05% NaF and 0.1% NaF and twice/day of 0.02% NaF solutions. Four different pH: 4.0. 5.0, 6.0 and 7.0 were used. Next, SMH test was again used to determine the surface microhardness percentage change (%SMH). Data obtained for %SMH were homogeneous and passed through variance analyses and Tukey's test (5%) as far as fluoride concentrations and pH. Resulls:The results showed that pH influenced %SMH in 0.02% NaF and 0.05% NaF solutions with pH 4.0, which had less mineral loss compared to pH 7.0 (p̃0.05). The 0.02% NaF - pH 4.0, and 0.05% NaF- pH 7.0 groups showed similar results (p>0.05). A dose-response relationship was observed among the tested solutions, with better anticariogenic effect for the 0.1% NaF solution. Conclusion: The results suggest that the addition of citric acid to acidulate mouth rinses reduce mineral loss.
publishDate 2006
dc.date.none.fl_str_mv 2006-12-01
2014-05-27T11:22:04Z
2014-05-27T11:22:04Z
2015-12-07T15:29:50Z
2015-12-07T15:29:50Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1678-77572006000400004
Journal of Applied Oral Science, v. 14, n. 4, p. 233-237, 2006.
1678-7757
1678-7765
http://hdl.handle.net/11449/154119
10.1590/S1678-77572006000400004
S1678-77572006000400004
2-s2.0-48249096248
2-s2.0-48249096248.pdf
6844354149917957
19089268
PMC4327478
0000-0002-8159-4853
url http://dx.doi.org/10.1590/S1678-77572006000400004
http://hdl.handle.net/11449/154119
identifier_str_mv Journal of Applied Oral Science, v. 14, n. 4, p. 233-237, 2006.
1678-7757
1678-7765
10.1590/S1678-77572006000400004
S1678-77572006000400004
2-s2.0-48249096248
2-s2.0-48249096248.pdf
6844354149917957
19089268
PMC4327478
0000-0002-8159-4853
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Applied Oral Science
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0,645
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 233-237
application/pdf
dc.publisher.none.fl_str_mv Journal Of Applied Oral Science : Revista Fob
publisher.none.fl_str_mv Journal Of Applied Oral Science : Revista Fob
dc.source.none.fl_str_mv Scopus
PubMed
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
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instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
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