Autonomic regulation of heart rate during specific dynamic action associated with digestion in the bullfrog Lithobates catesbeianus
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Publication Date: | 2015 |
Other Authors: | , |
Format: | Article |
Language: | eng |
Source: | Repositório Institucional da UNESP |
Download full: | http://dx.doi.org/10.1590/S1984-46702015000600009 http://hdl.handle.net/11449/161113 |
Summary: | Feeding causes a substantial rise in the aerobic metabolism of all vertebrates, which is met by a rise in heart rate to secure adequate oxygen delivery, as well as intestinal nutrient absorption and transport between organs. To study the autonomic regulation of this postprandial tachycardia in an amphibian, we placed arterial catheters in individuals of the bullfrog, Lithobates catesbeianus (Shaw, 1802), to measure their blood pressure and heart rate. Heart rate in experimental subjects increased from a fasting value of 42.5 +/- 2.5 to 52.5 +/- 1.6 and 57.5 +/- 2.1 min(-1) at 24 and 33 hours, respectively, after meals that corresponded to 5% of their body weight. Using an infusion of atropine and propranolol, we demonstrated that part of the postprandial tachycardia can be ascribed to a progressive decrease in parasympathetic tone (26 +/- 5% in fasting frogs to 6 +/- 5% by 33 hours into digestion), whereas the sympathetic tone remained unaltered at approximately 20%. In addition to the withdrawal of vagal tone, digestion was also associated with an increase in the heart rate upon double-blockade (i.e., the combination of atropine and propranolol) from a fasting value of 44.5 +/- 0.9 to 50.8 +/- 1.9 min(-1) at 33 hours. This indicates that the postprandial tachycardia in frogs, as previously demonstrated for snakes, is partially governed by excitation of non adrenergic, non cholinergic (NANC) factors. |
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Autonomic regulation of heart rate during specific dynamic action associated with digestion in the bullfrog Lithobates catesbeianusAdrenergiccholinergicpostprandial tachycardiaFeeding causes a substantial rise in the aerobic metabolism of all vertebrates, which is met by a rise in heart rate to secure adequate oxygen delivery, as well as intestinal nutrient absorption and transport between organs. To study the autonomic regulation of this postprandial tachycardia in an amphibian, we placed arterial catheters in individuals of the bullfrog, Lithobates catesbeianus (Shaw, 1802), to measure their blood pressure and heart rate. Heart rate in experimental subjects increased from a fasting value of 42.5 +/- 2.5 to 52.5 +/- 1.6 and 57.5 +/- 2.1 min(-1) at 24 and 33 hours, respectively, after meals that corresponded to 5% of their body weight. Using an infusion of atropine and propranolol, we demonstrated that part of the postprandial tachycardia can be ascribed to a progressive decrease in parasympathetic tone (26 +/- 5% in fasting frogs to 6 +/- 5% by 33 hours into digestion), whereas the sympathetic tone remained unaltered at approximately 20%. In addition to the withdrawal of vagal tone, digestion was also associated with an increase in the heart rate upon double-blockade (i.e., the combination of atropine and propranolol) from a fasting value of 44.5 +/- 0.9 to 50.8 +/- 1.9 min(-1) at 33 hours. This indicates that the postprandial tachycardia in frogs, as previously demonstrated for snakes, is partially governed by excitation of non adrenergic, non cholinergic (NANC) factors.Danish Research CouncilUniv Estadual Paulista, Inst Biociencias, Dept Zool, BR-13506900 Rio Claro, SP, BrazilAarhus Univ, Zoophysiol, Dept Biosci, DK-8000 Aarhus C, DenmarkUniv Estadual Paulista, Inst Biociencias, Dept Zool, BR-13506900 Rio Claro, SP, BrazilSoc Brasileira Zoologia, Univ Federal ParanaUniversidade Estadual Paulista (Unesp)Aarhus UnivClaesson, Debora [UNESP]Abe, Augusto Shinya [UNESP]Wang, Tobias [UNESP]2018-11-26T16:19:10Z2018-11-26T16:19:10Z2015-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article492-496application/pdfhttp://dx.doi.org/10.1590/S1984-46702015000600009Zoologia. Curitiba: Soc Brasileira Zoologia, Univ Federal Parana, v. 32, n. 6, p. 492-496, 2015.1984-4670http://hdl.handle.net/11449/16111310.1590/S1984-46702015000600009S1984-46702015000600492WOS:000367760900009S1984-46702015000600492.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengZoologia0,405info:eu-repo/semantics/openAccess2024-01-24T06:33:12Zoai:repositorio.unesp.br:11449/161113Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-01-24T06:33:12Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Autonomic regulation of heart rate during specific dynamic action associated with digestion in the bullfrog Lithobates catesbeianus |
title |
Autonomic regulation of heart rate during specific dynamic action associated with digestion in the bullfrog Lithobates catesbeianus |
spellingShingle |
Autonomic regulation of heart rate during specific dynamic action associated with digestion in the bullfrog Lithobates catesbeianus Claesson, Debora [UNESP] Adrenergic cholinergic postprandial tachycardia |
title_short |
Autonomic regulation of heart rate during specific dynamic action associated with digestion in the bullfrog Lithobates catesbeianus |
title_full |
Autonomic regulation of heart rate during specific dynamic action associated with digestion in the bullfrog Lithobates catesbeianus |
title_fullStr |
Autonomic regulation of heart rate during specific dynamic action associated with digestion in the bullfrog Lithobates catesbeianus |
title_full_unstemmed |
Autonomic regulation of heart rate during specific dynamic action associated with digestion in the bullfrog Lithobates catesbeianus |
title_sort |
Autonomic regulation of heart rate during specific dynamic action associated with digestion in the bullfrog Lithobates catesbeianus |
author |
Claesson, Debora [UNESP] |
author_facet |
Claesson, Debora [UNESP] Abe, Augusto Shinya [UNESP] Wang, Tobias [UNESP] |
author_role |
author |
author2 |
Abe, Augusto Shinya [UNESP] Wang, Tobias [UNESP] |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Aarhus Univ |
dc.contributor.author.fl_str_mv |
Claesson, Debora [UNESP] Abe, Augusto Shinya [UNESP] Wang, Tobias [UNESP] |
dc.subject.por.fl_str_mv |
Adrenergic cholinergic postprandial tachycardia |
topic |
Adrenergic cholinergic postprandial tachycardia |
description |
Feeding causes a substantial rise in the aerobic metabolism of all vertebrates, which is met by a rise in heart rate to secure adequate oxygen delivery, as well as intestinal nutrient absorption and transport between organs. To study the autonomic regulation of this postprandial tachycardia in an amphibian, we placed arterial catheters in individuals of the bullfrog, Lithobates catesbeianus (Shaw, 1802), to measure their blood pressure and heart rate. Heart rate in experimental subjects increased from a fasting value of 42.5 +/- 2.5 to 52.5 +/- 1.6 and 57.5 +/- 2.1 min(-1) at 24 and 33 hours, respectively, after meals that corresponded to 5% of their body weight. Using an infusion of atropine and propranolol, we demonstrated that part of the postprandial tachycardia can be ascribed to a progressive decrease in parasympathetic tone (26 +/- 5% in fasting frogs to 6 +/- 5% by 33 hours into digestion), whereas the sympathetic tone remained unaltered at approximately 20%. In addition to the withdrawal of vagal tone, digestion was also associated with an increase in the heart rate upon double-blockade (i.e., the combination of atropine and propranolol) from a fasting value of 44.5 +/- 0.9 to 50.8 +/- 1.9 min(-1) at 33 hours. This indicates that the postprandial tachycardia in frogs, as previously demonstrated for snakes, is partially governed by excitation of non adrenergic, non cholinergic (NANC) factors. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-12-01 2018-11-26T16:19:10Z 2018-11-26T16:19:10Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S1984-46702015000600009 Zoologia. Curitiba: Soc Brasileira Zoologia, Univ Federal Parana, v. 32, n. 6, p. 492-496, 2015. 1984-4670 http://hdl.handle.net/11449/161113 10.1590/S1984-46702015000600009 S1984-46702015000600492 WOS:000367760900009 S1984-46702015000600492.pdf |
url |
http://dx.doi.org/10.1590/S1984-46702015000600009 http://hdl.handle.net/11449/161113 |
identifier_str_mv |
Zoologia. Curitiba: Soc Brasileira Zoologia, Univ Federal Parana, v. 32, n. 6, p. 492-496, 2015. 1984-4670 10.1590/S1984-46702015000600009 S1984-46702015000600492 WOS:000367760900009 S1984-46702015000600492.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Zoologia 0,405 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
492-496 application/pdf |
dc.publisher.none.fl_str_mv |
Soc Brasileira Zoologia, Univ Federal Parana |
publisher.none.fl_str_mv |
Soc Brasileira Zoologia, Univ Federal Parana |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1797790384809574400 |