Biofilmes orais como um possível fator de risco ao câncer bucal

• Autor(a) principal: Ciesielski, Francisco Isaak Nicolas [UNESP]
• Data de Publicação: 2010
• Outros Autores: Biasoli, Éder Ricardo [UNESP], Goiato, Marcelo Coelho [UNESP], De Carli, João Paulo, Silva, Soluete Oliveira da, Linden, Maria Salete Sandini Linden, Trentin, Micheline Sandini, Miyahara, Glauco Issamu [UNESP]
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.15603/2176-1000/odonto.v18n36p127-138; http://hdl.handle.net/11449/154058
• topic: Microbiology; Mouth neoplasms; Dental plaque; Microbiologia; Câncer bucal; Biofilme dentário

Introduction: much studies regarding risk factors associated with oral cancer. Factors such as smoking and alcohol and solar radiation are well established, but others, such as bacterial influence in the development or progression of a tumor still remain unexplained. Interest in the possible relationship between bacteria and different stages of cancer development has increased since the classification of H. pylori by the WHO as a definite carcinogen. Subsequently, links between infection and the onset of cancer in various sites in the body were discovered. Review of literature: this literature review attempts to show the influence of poor oral hygiene, with consequent bacterial accumulation as a possible important risk factor for the initiation and development of mouth cancer, and correlate the possible mechanisms by which bacteria can initiate or promote carcinogenesis. Conclusion: there is much evidence that bacteria in the oral cavity and periodontopathic are present in tumor tissue, however, still can not affirm that these bacteria initiate or promote carcinogenesis.