Experiência clínica com o uso de sedativos em terapia intensiva. Estudo retrospectivo
Autor(a) principal: | |
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Data de Publicação: | 2002 |
Outros Autores: | |
Tipo de documento: | Artigo |
Idioma: | por eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://hdl.handle.net/11449/224508 |
Resumo: | Background and Objectives - Among the most frequent indications for Intensive Care Unit patients sedation, one may mention artificial ventilation installation and maintenance, anxiety and uncomfortable or painful procedures. This retrospective study aimed at evaluating most common sedation indications and techniques for severe patients admitted to the Surgical Intensive Care Unit, Escola Paulista de Medicina (EPM/UNIFESP) during an 11-month period. Methods - After excluding patients remaining in the ICU for less than 24 hours and those without the necessary evaluation to determine their severity index (APACHE II), the sample was reduced to 307 patients. Most common techniques, sedation indications and neuromuscular blockers association were evaluated. Results - Sedation was administered to 37.4% of patients. Psychiatric disorders, such as delirium, agitation, fear and anxiety, were some indications for sedation and corresponded to 25.77% of all indications. Most ventilated patients also needed sedative agents and mechanical ventilation installation and maintenance represented most indications, or approximately 57.73% of all sedated patients. Procedures, such as tracheal intubation and bronchoscopy, represented 11.34% of all indications and metabolic control (barbiturate coma and tetanus) represented 5.15% of the cases. Most common sedative techniques included opioids alone or associated to benzodiazepines. In this study, fentanyl alone was used in 58% of the cases, and fentanyl plus midazolam in 21.64% of patients. Haloperidol, diazepam, propofol and thiopental added up 19.5%. Neuromuscular blockers were used in 22.7% of mechanically in ventilated patients. Conclusions - Sedation is a common therapeutic resource for intensive care and is widely used to help mechanical ventilation and to treat psychiatric disorders. Fentanyl, alone or in association with midazolam, was the most widely used agent. |
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Experiência clínica com o uso de sedativos em terapia intensiva. Estudo retrospectivoClinical experience with sedatives in the intensive care unit. A retrospective studyIntensive CareSedationBackground and Objectives - Among the most frequent indications for Intensive Care Unit patients sedation, one may mention artificial ventilation installation and maintenance, anxiety and uncomfortable or painful procedures. This retrospective study aimed at evaluating most common sedation indications and techniques for severe patients admitted to the Surgical Intensive Care Unit, Escola Paulista de Medicina (EPM/UNIFESP) during an 11-month period. Methods - After excluding patients remaining in the ICU for less than 24 hours and those without the necessary evaluation to determine their severity index (APACHE II), the sample was reduced to 307 patients. Most common techniques, sedation indications and neuromuscular blockers association were evaluated. Results - Sedation was administered to 37.4% of patients. Psychiatric disorders, such as delirium, agitation, fear and anxiety, were some indications for sedation and corresponded to 25.77% of all indications. Most ventilated patients also needed sedative agents and mechanical ventilation installation and maintenance represented most indications, or approximately 57.73% of all sedated patients. Procedures, such as tracheal intubation and bronchoscopy, represented 11.34% of all indications and metabolic control (barbiturate coma and tetanus) represented 5.15% of the cases. Most common sedative techniques included opioids alone or associated to benzodiazepines. In this study, fentanyl alone was used in 58% of the cases, and fentanyl plus midazolam in 21.64% of patients. Haloperidol, diazepam, propofol and thiopental added up 19.5%. Neuromuscular blockers were used in 22.7% of mechanically in ventilated patients. Conclusions - Sedation is a common therapeutic resource for intensive care and is widely used to help mechanical ventilation and to treat psychiatric disorders. Fentanyl, alone or in association with midazolam, was the most widely used agent.Depto. Anestesiologia da FMB-UNESP, Distrito de Rubião Junior, 18618-970 Botucatu, SPDisciplina de Anestesiologia Dor Ter. Inten. Cir. EPM/UNIFESP, Botucatu, SPDepto. Anestesiologia da FMB-UNESP, Distrito de Rubião Junior, 18618-970 Botucatu, SPUniversidade Estadual Paulista (UNESP)Universidade Federal de São Paulo (UNIFESP)Rodrigues Jr., Geraldo Rolim [UNESP]Do Amaral, José Luiz Gomes2022-04-28T19:56:58Z2022-04-28T19:56:58Z2002-11-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article747-755Revista Brasileira de Anestesiologia, v. 52, n. 6, p. 747-755, 2002.0034-7094http://hdl.handle.net/11449/2245082-s2.0-17144451752Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporengRevista Brasileira de Anestesiologiainfo:eu-repo/semantics/openAccess2022-04-28T19:56:58Zoai:repositorio.unesp.br:11449/224508Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-04-28T19:56:58Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Experiência clínica com o uso de sedativos em terapia intensiva. Estudo retrospectivo Clinical experience with sedatives in the intensive care unit. A retrospective study |
title |
Experiência clínica com o uso de sedativos em terapia intensiva. Estudo retrospectivo |
spellingShingle |
Experiência clínica com o uso de sedativos em terapia intensiva. Estudo retrospectivo Rodrigues Jr., Geraldo Rolim [UNESP] Intensive Care Sedation |
title_short |
Experiência clínica com o uso de sedativos em terapia intensiva. Estudo retrospectivo |
title_full |
Experiência clínica com o uso de sedativos em terapia intensiva. Estudo retrospectivo |
title_fullStr |
Experiência clínica com o uso de sedativos em terapia intensiva. Estudo retrospectivo |
title_full_unstemmed |
Experiência clínica com o uso de sedativos em terapia intensiva. Estudo retrospectivo |
title_sort |
Experiência clínica com o uso de sedativos em terapia intensiva. Estudo retrospectivo |
author |
Rodrigues Jr., Geraldo Rolim [UNESP] |
author_facet |
Rodrigues Jr., Geraldo Rolim [UNESP] Do Amaral, José Luiz Gomes |
author_role |
author |
author2 |
Do Amaral, José Luiz Gomes |
author2_role |
author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) Universidade Federal de São Paulo (UNIFESP) |
dc.contributor.author.fl_str_mv |
Rodrigues Jr., Geraldo Rolim [UNESP] Do Amaral, José Luiz Gomes |
dc.subject.por.fl_str_mv |
Intensive Care Sedation |
topic |
Intensive Care Sedation |
description |
Background and Objectives - Among the most frequent indications for Intensive Care Unit patients sedation, one may mention artificial ventilation installation and maintenance, anxiety and uncomfortable or painful procedures. This retrospective study aimed at evaluating most common sedation indications and techniques for severe patients admitted to the Surgical Intensive Care Unit, Escola Paulista de Medicina (EPM/UNIFESP) during an 11-month period. Methods - After excluding patients remaining in the ICU for less than 24 hours and those without the necessary evaluation to determine their severity index (APACHE II), the sample was reduced to 307 patients. Most common techniques, sedation indications and neuromuscular blockers association were evaluated. Results - Sedation was administered to 37.4% of patients. Psychiatric disorders, such as delirium, agitation, fear and anxiety, were some indications for sedation and corresponded to 25.77% of all indications. Most ventilated patients also needed sedative agents and mechanical ventilation installation and maintenance represented most indications, or approximately 57.73% of all sedated patients. Procedures, such as tracheal intubation and bronchoscopy, represented 11.34% of all indications and metabolic control (barbiturate coma and tetanus) represented 5.15% of the cases. Most common sedative techniques included opioids alone or associated to benzodiazepines. In this study, fentanyl alone was used in 58% of the cases, and fentanyl plus midazolam in 21.64% of patients. Haloperidol, diazepam, propofol and thiopental added up 19.5%. Neuromuscular blockers were used in 22.7% of mechanically in ventilated patients. Conclusions - Sedation is a common therapeutic resource for intensive care and is widely used to help mechanical ventilation and to treat psychiatric disorders. Fentanyl, alone or in association with midazolam, was the most widely used agent. |
publishDate |
2002 |
dc.date.none.fl_str_mv |
2002-11-01 2022-04-28T19:56:58Z 2022-04-28T19:56:58Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
Revista Brasileira de Anestesiologia, v. 52, n. 6, p. 747-755, 2002. 0034-7094 http://hdl.handle.net/11449/224508 2-s2.0-17144451752 |
identifier_str_mv |
Revista Brasileira de Anestesiologia, v. 52, n. 6, p. 747-755, 2002. 0034-7094 2-s2.0-17144451752 |
url |
http://hdl.handle.net/11449/224508 |
dc.language.iso.fl_str_mv |
por eng |
language |
por eng |
dc.relation.none.fl_str_mv |
Revista Brasileira de Anestesiologia |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
747-755 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1797790069012037632 |