Retrospective serological survey for influenza in horses from Brazil
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1007/s42770-020-00398-8 http://hdl.handle.net/11449/206820 |
Resumo: | Equine influenza (EI) virus is one of the most economically important pathogens of respiratory diseases of horses worldwide. Despite availability of vaccines for control of EI, the highly contagious nature and variability properties of the virus mean global outbreaks occur. Thus, continuous surveillance programs, including seroprevalence studies of disease in different countries, may contribute to better control of the disease. In this study, the seroprevalence of equine influenza in 850 horses from Brazil was investigated. The serodiagnosis was based on the single radial hemolysis (SRH) assay using influenza A/equine/Richmond/1/2007 (H3N8) antigen. Antibodies against A/equine/Richmond/1/07 (H3N8) were detected in 44.7% (380/850, 95% CI: 41.4–48.1%) of horses. Seroprevalence was significantly lower (p = 0.001) in younger animals (< 5 years, 38.6%) than in “adult” animals (5–14 years, 52.1%). There was also a significant relationship between the year of sampling and seroprevalence (p < 0.0005). The mean SRH antibody value was 42.0 mm2 (range 4–238.9 mm2), with the majority of horses (95.3%) having an SRH value ≤ 150 mm2, which is considered an insufficient level for protection of equine hosts against influenza infections and potential virus shedding. These findings indicate the need to reinforce preventive/control measures against equine influenza in Brazil. |
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Retrospective serological survey for influenza in horses from BrazilHorsesInfluenza virus H3N8SerodiagnosisSeroprevalenceEquine influenza (EI) virus is one of the most economically important pathogens of respiratory diseases of horses worldwide. Despite availability of vaccines for control of EI, the highly contagious nature and variability properties of the virus mean global outbreaks occur. Thus, continuous surveillance programs, including seroprevalence studies of disease in different countries, may contribute to better control of the disease. In this study, the seroprevalence of equine influenza in 850 horses from Brazil was investigated. The serodiagnosis was based on the single radial hemolysis (SRH) assay using influenza A/equine/Richmond/1/2007 (H3N8) antigen. Antibodies against A/equine/Richmond/1/07 (H3N8) were detected in 44.7% (380/850, 95% CI: 41.4–48.1%) of horses. Seroprevalence was significantly lower (p = 0.001) in younger animals (< 5 years, 38.6%) than in “adult” animals (5–14 years, 52.1%). There was also a significant relationship between the year of sampling and seroprevalence (p < 0.0005). The mean SRH antibody value was 42.0 mm2 (range 4–238.9 mm2), with the majority of horses (95.3%) having an SRH value ≤ 150 mm2, which is considered an insufficient level for protection of equine hosts against influenza infections and potential virus shedding. These findings indicate the need to reinforce preventive/control measures against equine influenza in Brazil.School of Veterinary Medicine and Science University of NottinghamInfectious Diseases of Domestic Animals Department of Animal Production and Preventive Veterinary Medicine School of Veterinary Medicine and Animal Science São Paulo State University-UNESPTechnology Faculty-FATECInfectious Diseases of Domestic Animals Department of Animal Production and Preventive Veterinary Medicine School of Veterinary Medicine and Animal Science São Paulo State University-UNESPUniversity of NottinghamUniversidade Estadual Paulista (Unesp)Technology Faculty-FATECDaly, J. M.Megid, J. [UNESP]Langoni, H. [UNESP]de Nardi Júnior, G.Ribeiro, M. G. [UNESP]2021-06-25T10:44:23Z2021-06-25T10:44:23Z2021-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article461-466http://dx.doi.org/10.1007/s42770-020-00398-8Brazilian Journal of Microbiology, v. 52, n. 1, p. 461-466, 2021.1678-44051517-8382http://hdl.handle.net/11449/20682010.1007/s42770-020-00398-82-s2.0-85095958593Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Journal of Microbiologyinfo:eu-repo/semantics/openAccess2021-10-23T08:32:22Zoai:repositorio.unesp.br:11449/206820Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T08:32:22Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Retrospective serological survey for influenza in horses from Brazil |
title |
Retrospective serological survey for influenza in horses from Brazil |
spellingShingle |
Retrospective serological survey for influenza in horses from Brazil Daly, J. M. Horses Influenza virus H3N8 Serodiagnosis Seroprevalence |
title_short |
Retrospective serological survey for influenza in horses from Brazil |
title_full |
Retrospective serological survey for influenza in horses from Brazil |
title_fullStr |
Retrospective serological survey for influenza in horses from Brazil |
title_full_unstemmed |
Retrospective serological survey for influenza in horses from Brazil |
title_sort |
Retrospective serological survey for influenza in horses from Brazil |
author |
Daly, J. M. |
author_facet |
Daly, J. M. Megid, J. [UNESP] Langoni, H. [UNESP] de Nardi Júnior, G. Ribeiro, M. G. [UNESP] |
author_role |
author |
author2 |
Megid, J. [UNESP] Langoni, H. [UNESP] de Nardi Júnior, G. Ribeiro, M. G. [UNESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
University of Nottingham Universidade Estadual Paulista (Unesp) Technology Faculty-FATEC |
dc.contributor.author.fl_str_mv |
Daly, J. M. Megid, J. [UNESP] Langoni, H. [UNESP] de Nardi Júnior, G. Ribeiro, M. G. [UNESP] |
dc.subject.por.fl_str_mv |
Horses Influenza virus H3N8 Serodiagnosis Seroprevalence |
topic |
Horses Influenza virus H3N8 Serodiagnosis Seroprevalence |
description |
Equine influenza (EI) virus is one of the most economically important pathogens of respiratory diseases of horses worldwide. Despite availability of vaccines for control of EI, the highly contagious nature and variability properties of the virus mean global outbreaks occur. Thus, continuous surveillance programs, including seroprevalence studies of disease in different countries, may contribute to better control of the disease. In this study, the seroprevalence of equine influenza in 850 horses from Brazil was investigated. The serodiagnosis was based on the single radial hemolysis (SRH) assay using influenza A/equine/Richmond/1/2007 (H3N8) antigen. Antibodies against A/equine/Richmond/1/07 (H3N8) were detected in 44.7% (380/850, 95% CI: 41.4–48.1%) of horses. Seroprevalence was significantly lower (p = 0.001) in younger animals (< 5 years, 38.6%) than in “adult” animals (5–14 years, 52.1%). There was also a significant relationship between the year of sampling and seroprevalence (p < 0.0005). The mean SRH antibody value was 42.0 mm2 (range 4–238.9 mm2), with the majority of horses (95.3%) having an SRH value ≤ 150 mm2, which is considered an insufficient level for protection of equine hosts against influenza infections and potential virus shedding. These findings indicate the need to reinforce preventive/control measures against equine influenza in Brazil. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-06-25T10:44:23Z 2021-06-25T10:44:23Z 2021-03-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1007/s42770-020-00398-8 Brazilian Journal of Microbiology, v. 52, n. 1, p. 461-466, 2021. 1678-4405 1517-8382 http://hdl.handle.net/11449/206820 10.1007/s42770-020-00398-8 2-s2.0-85095958593 |
url |
http://dx.doi.org/10.1007/s42770-020-00398-8 http://hdl.handle.net/11449/206820 |
identifier_str_mv |
Brazilian Journal of Microbiology, v. 52, n. 1, p. 461-466, 2021. 1678-4405 1517-8382 10.1007/s42770-020-00398-8 2-s2.0-85095958593 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian Journal of Microbiology |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
461-466 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799965537181106176 |