Adesivo tecidual de fibrina e sua aplicação na implantodontia

• Autor(a) principal: Alves Rezende, Maria Cristina Rosifini [UNESP]
• Data de Publicação: 2014
• Outros Autores: Wada, Criatiane Mayumi [UNESP], Capalbo, Leticia Cabrera, Gonçalves, Vanessa Mosca
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://www.archhealthinvestigation.com.br/index.php/ArcHI/article/view/867; http://hdl.handle.net/11449/133225
• topic: Fibrin tissue adhesive; Dental implants; Biocompatible materials; Adhesivo de tejido de fibrina; Implantes dentales; Materiales biocompatibles; Adesivo tecidual de fibrina; Implantes dentários; Materiais biocompatíveis

The purpose of this literature review was to evaluate the use of fibrin tissue adhesive in implant dentistry. Materials and Methods: A literature search of Medline-PubMed for articles published, describing the use of fibrin tissue adhesive in implant dentistry was performed and articles were critically reviewed. Results: The literature review reveals clinical trials and experimental studies with regard to the use of fibrin tissue adhesive in implant dentistry. This material consists of 2 components: highly purified, freeze-dried human fibrinogen with factor XIII and a starter solution containing human thrombin. Clotting factor XIII is admitted for reinforcement of the fibrin network. The components are reconstituted before use and when mixed form a clot by mimicking the terminal phase of the physiological clotting cascade. Several studies showed that fibrin tissue adhesive is fully absorbed by macrophages within 2 weeks of application. Adhesive fibrin tissue may be used for to prevent bone loss, to create contour in the periimplant soft tissue and osseous tissue, to sculpt emergence profile for prosthetic components and to mimic tissue architecture. In the last years fibrin tissue adhesive also find use as material for the controlled delivery of drugs and biologics. Conclusions: The fibrin tissue adhesive presents good properties such as biocompatibility, hemostatic properties and ability to break down like the physiologic clot. This material, alone or associated with other materials, can be used with the implants immediately after extraction. In this condition it brings the necessary anchoring and efficient maintenance of osseous/mucosal contour, which it is important for the clinical success.