Evaluación del comportamiento biológico de tres cementos obturadores endodónticos en tejido subcutáneo de ratones

• Main Author: Moraes, Sergio Herrero
• Publication Date: 2012
• Other Authors: Tanomaru Filho, Mario [UNESP], Chavez-Andrade, Gisele Moraima [UNESP], Silva, Guilherme Ferreira da [UNESP], Tanomaru, Juliane Mario Guerreiro [UNESP]
• Format: Article
• Language: spa
• Source: Repositório Institucional da UNESP
• Download full: http://www.actaodontologica.com/ediciones/2012/3/art8.asp; http://hdl.handle.net/11449/125862
• topic: Root canal obturation; Toxicity; Endodontic sealers; Obturación del conducto radicular; Biocompatibilidad; Cementos endodónticos

The aim of this study was to evaluate the biological behavior of the root canal filling sealers: Endofill, Endomethasone and Sealer 26 when in contact with the subcutaneous connective tissue of rat. For the study one control and three experimental groups were used. A total of 15 animals were divided into 5 for each period: 7, 21, and 60 days. The obtained histological sections were processed and stained using the hematoxiline & eosine technique. The histological sections were subjective and comparatively analyzed using optic microscopy. The intensity of the inflammatory reaction and the level of fibrosis of the tissue were registered. The results were registered in scores and statistical analysis by KRUSKAL-WALLIS p<0,05 and MILLER methods. The statistical analysis revealed that in the period of 60 days, there was statistical significance to group II (Endofill) between group (control) and III (Endomethasone) with mononuclear cells into connective tissue. All materials promoted inflammatory reaction more intense at 7 and 21 days with the Endomethasone showing the best results.