Septic arthritis: immunopathogenesis, experimental models and therapy

Detalhes bibliográficos
Autor(a) principal: Colavite, Priscila Maria
Data de Publicação: 2014
Outros Autores: Sartori, Alexandrina
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1186/1678-9199-20-19
http://hdl.handle.net/11449/130497
Resumo: Septic arthritis is an inflammatory disease of the joints that is started by an infection whose most common agent is Staphylococcus aureus. In this review we discuss some of the most arthritogenic bacterial factors and the contribution of innate and specific immune mechanisms to joint destruction. Special emphasis is given to the induction of experimental arthritis by S. aureus in mice. The improvement of therapy by association of antibiotics with down-modulation of immunity is also included.
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spelling Septic arthritis: immunopathogenesis, experimental models and therapySeptic arthritisStaphylococcus aureusMiceSeptic arthritis is an inflammatory disease of the joints that is started by an infection whose most common agent is Staphylococcus aureus. In this review we discuss some of the most arthritogenic bacterial factors and the contribution of innate and specific immune mechanisms to joint destruction. Special emphasis is given to the induction of experimental arthritis by S. aureus in mice. The improvement of therapy by association of antibiotics with down-modulation of immunity is also included.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Universidade Estadual Paulista Instituto de Biociências Departamento de Microbiologia e ImunologiaUniversidade Estadual Paulista Instituto de Biociências Departamento de Microbiologia e ImunologiaCentro de Estudos de Venenos e Animais Peçonhentos - CEVAP, Universidade Estadual Paulista - UNESPUniversidade Estadual Paulista (Unesp)Colavite, Priscila MariaSartori, Alexandrina2015-02-02T12:39:36Z2015-02-02T12:39:36Z2014-06-06info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article01-08application/pdfhttp://dx.doi.org/10.1186/1678-9199-20-19Journal of Venomous Animals and Toxins including Tropical Diseases. Centro de Estudos de Venenos e Animais Peçonhentos - CEVAP, Universidade Estadual Paulista - UNESP, v. 20, p. 01-08, 2014.1678-9199http://hdl.handle.net/11449/13049710.1186/1678-9199-20-19S1678-91992014000200205WOS:000335792300001S1678-91992014000200205.pdf4977572416129527SciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Venomous Animals and Toxins including Tropical Diseases1.7820,573info:eu-repo/semantics/openAccess2024-01-27T07:00:04Zoai:repositorio.unesp.br:11449/130497Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-01-27T07:00:04Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Septic arthritis: immunopathogenesis, experimental models and therapy
title Septic arthritis: immunopathogenesis, experimental models and therapy
spellingShingle Septic arthritis: immunopathogenesis, experimental models and therapy
Colavite, Priscila Maria
Septic arthritis
Staphylococcus aureus
Mice
title_short Septic arthritis: immunopathogenesis, experimental models and therapy
title_full Septic arthritis: immunopathogenesis, experimental models and therapy
title_fullStr Septic arthritis: immunopathogenesis, experimental models and therapy
title_full_unstemmed Septic arthritis: immunopathogenesis, experimental models and therapy
title_sort Septic arthritis: immunopathogenesis, experimental models and therapy
author Colavite, Priscila Maria
author_facet Colavite, Priscila Maria
Sartori, Alexandrina
author_role author
author2 Sartori, Alexandrina
author2_role author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Colavite, Priscila Maria
Sartori, Alexandrina
dc.subject.por.fl_str_mv Septic arthritis
Staphylococcus aureus
Mice
topic Septic arthritis
Staphylococcus aureus
Mice
description Septic arthritis is an inflammatory disease of the joints that is started by an infection whose most common agent is Staphylococcus aureus. In this review we discuss some of the most arthritogenic bacterial factors and the contribution of innate and specific immune mechanisms to joint destruction. Special emphasis is given to the induction of experimental arthritis by S. aureus in mice. The improvement of therapy by association of antibiotics with down-modulation of immunity is also included.
publishDate 2014
dc.date.none.fl_str_mv 2014-06-06
2015-02-02T12:39:36Z
2015-02-02T12:39:36Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1186/1678-9199-20-19
Journal of Venomous Animals and Toxins including Tropical Diseases. Centro de Estudos de Venenos e Animais Peçonhentos - CEVAP, Universidade Estadual Paulista - UNESP, v. 20, p. 01-08, 2014.
1678-9199
http://hdl.handle.net/11449/130497
10.1186/1678-9199-20-19
S1678-91992014000200205
WOS:000335792300001
S1678-91992014000200205.pdf
4977572416129527
url http://dx.doi.org/10.1186/1678-9199-20-19
http://hdl.handle.net/11449/130497
identifier_str_mv Journal of Venomous Animals and Toxins including Tropical Diseases. Centro de Estudos de Venenos e Animais Peçonhentos - CEVAP, Universidade Estadual Paulista - UNESP, v. 20, p. 01-08, 2014.
1678-9199
10.1186/1678-9199-20-19
S1678-91992014000200205
WOS:000335792300001
S1678-91992014000200205.pdf
4977572416129527
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Venomous Animals and Toxins including Tropical Diseases
1.782
0,573
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 01-08
application/pdf
dc.publisher.none.fl_str_mv Centro de Estudos de Venenos e Animais Peçonhentos - CEVAP, Universidade Estadual Paulista - UNESP
publisher.none.fl_str_mv Centro de Estudos de Venenos e Animais Peçonhentos - CEVAP, Universidade Estadual Paulista - UNESP
dc.source.none.fl_str_mv SciELO
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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