Surface modification of calcium phosphate scaffolds with antimicrobial agents for bone tissue engineering
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Capítulo de livro |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/B978-0-323-85883-0.00017-X http://hdl.handle.net/11449/247432 |
Resumo: | This chapter provides an overview about some innovative strategies to functionalize calcium phosphate scaffolds’ surfaces by using antimicrobial agents to combat osteomyelitis. The scaffolds can be obtained by different techniques and must fulfill some requirements, including open and interconnected porosity, mechanical and biological properties, and biomaterial requirements. Also, special attention was given to understanding the mechanism of action of antimicrobial agents (antibiotics, nanoparticles (NPs), and photosensitizers (PS)) that is essential to enhance the development of efficient antimicrobial scaffolds. Finally, this chapter reports on recent results obtained by our group regarding the development of β-tricalcium phosphate (β-TCP) scaffolds with antibacterial properties afforded by the incorporation of silver nanoparticles and methylene blue. |
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Repositório Institucional da UNESP |
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2946 |
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Surface modification of calcium phosphate scaffolds with antimicrobial agents for bone tissue engineeringAntimicrobial agentsBone tissue engineeringCalcium phosphatesMultifunctional scaffoldsThis chapter provides an overview about some innovative strategies to functionalize calcium phosphate scaffolds’ surfaces by using antimicrobial agents to combat osteomyelitis. The scaffolds can be obtained by different techniques and must fulfill some requirements, including open and interconnected porosity, mechanical and biological properties, and biomaterial requirements. Also, special attention was given to understanding the mechanism of action of antimicrobial agents (antibiotics, nanoparticles (NPs), and photosensitizers (PS)) that is essential to enhance the development of efficient antimicrobial scaffolds. Finally, this chapter reports on recent results obtained by our group regarding the development of β-tricalcium phosphate (β-TCP) scaffolds with antibacterial properties afforded by the incorporation of silver nanoparticles and methylene blue.Federal University of São Paulo UNIFESP, SPFederal Institute of São Paulo IFSP, SPSão Paulo State University UNESP, SPSão Paulo State University UNESP, SPUniversidade de São Paulo (USP)IFSPUniversidade Estadual Paulista (UNESP)Barbosa, LucasOliveira, Rodrigo L.M.S.De Macedo, Erenilda F.Hurtado, Carolina R.Ramos, Lucas de P. [UNESP]Oliveira, Luciane D. [UNESP]Conceição, KatiaTada, Dayane B.Trichês, Eliandra de S.2023-07-29T13:15:54Z2023-07-29T13:15:54Z2023-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bookPart289-322http://dx.doi.org/10.1016/B978-0-323-85883-0.00017-XSurface Modification and Functionalization of Ceramic Composites, p. 289-322.http://hdl.handle.net/11449/24743210.1016/B978-0-323-85883-0.00017-X2-s2.0-85160178236Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengSurface Modification and Functionalization of Ceramic Compositesinfo:eu-repo/semantics/openAccess2023-07-29T13:15:54Zoai:repositorio.unesp.br:11449/247432Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-07-29T13:15:54Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Surface modification of calcium phosphate scaffolds with antimicrobial agents for bone tissue engineering |
title |
Surface modification of calcium phosphate scaffolds with antimicrobial agents for bone tissue engineering |
spellingShingle |
Surface modification of calcium phosphate scaffolds with antimicrobial agents for bone tissue engineering Barbosa, Lucas Antimicrobial agents Bone tissue engineering Calcium phosphates Multifunctional scaffolds |
title_short |
Surface modification of calcium phosphate scaffolds with antimicrobial agents for bone tissue engineering |
title_full |
Surface modification of calcium phosphate scaffolds with antimicrobial agents for bone tissue engineering |
title_fullStr |
Surface modification of calcium phosphate scaffolds with antimicrobial agents for bone tissue engineering |
title_full_unstemmed |
Surface modification of calcium phosphate scaffolds with antimicrobial agents for bone tissue engineering |
title_sort |
Surface modification of calcium phosphate scaffolds with antimicrobial agents for bone tissue engineering |
author |
Barbosa, Lucas |
author_facet |
Barbosa, Lucas Oliveira, Rodrigo L.M.S. De Macedo, Erenilda F. Hurtado, Carolina R. Ramos, Lucas de P. [UNESP] Oliveira, Luciane D. [UNESP] Conceição, Katia Tada, Dayane B. Trichês, Eliandra de S. |
author_role |
author |
author2 |
Oliveira, Rodrigo L.M.S. De Macedo, Erenilda F. Hurtado, Carolina R. Ramos, Lucas de P. [UNESP] Oliveira, Luciane D. [UNESP] Conceição, Katia Tada, Dayane B. Trichês, Eliandra de S. |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) IFSP Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Barbosa, Lucas Oliveira, Rodrigo L.M.S. De Macedo, Erenilda F. Hurtado, Carolina R. Ramos, Lucas de P. [UNESP] Oliveira, Luciane D. [UNESP] Conceição, Katia Tada, Dayane B. Trichês, Eliandra de S. |
dc.subject.por.fl_str_mv |
Antimicrobial agents Bone tissue engineering Calcium phosphates Multifunctional scaffolds |
topic |
Antimicrobial agents Bone tissue engineering Calcium phosphates Multifunctional scaffolds |
description |
This chapter provides an overview about some innovative strategies to functionalize calcium phosphate scaffolds’ surfaces by using antimicrobial agents to combat osteomyelitis. The scaffolds can be obtained by different techniques and must fulfill some requirements, including open and interconnected porosity, mechanical and biological properties, and biomaterial requirements. Also, special attention was given to understanding the mechanism of action of antimicrobial agents (antibiotics, nanoparticles (NPs), and photosensitizers (PS)) that is essential to enhance the development of efficient antimicrobial scaffolds. Finally, this chapter reports on recent results obtained by our group regarding the development of β-tricalcium phosphate (β-TCP) scaffolds with antibacterial properties afforded by the incorporation of silver nanoparticles and methylene blue. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-07-29T13:15:54Z 2023-07-29T13:15:54Z 2023-01-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/bookPart |
format |
bookPart |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/B978-0-323-85883-0.00017-X Surface Modification and Functionalization of Ceramic Composites, p. 289-322. http://hdl.handle.net/11449/247432 10.1016/B978-0-323-85883-0.00017-X 2-s2.0-85160178236 |
url |
http://dx.doi.org/10.1016/B978-0-323-85883-0.00017-X http://hdl.handle.net/11449/247432 |
identifier_str_mv |
Surface Modification and Functionalization of Ceramic Composites, p. 289-322. 10.1016/B978-0-323-85883-0.00017-X 2-s2.0-85160178236 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Surface Modification and Functionalization of Ceramic Composites |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
289-322 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799965632560627712 |