Interaction mechanism of plant-based nanoarchitectured materials with digestive enzymes of termites as target for pest control: Evidence from molecular docking simulation and in vitro studies
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.jhazmat.2020.123840 http://hdl.handle.net/11449/205171 |
Resumo: | The integration of nanotechnology for efficient pest management is gaining momentum to overcome the challenges and drawbacks of traditional approaches. However, studies pertaining to termite pest control using biosynthesized nanoparticles are seldom. The present study aims to highlight the following key points: a) green synthesis of AgNPs using Glochidion eriocarpum and their activity against wood-feeding termites, b) testing the hypothesis that AgNPs diminish digestive enzymes in termite gut through in silico analysis. The green synthesis route generated spherical PsAgNPs in the size range of 4-44.5 nm exhibiting higher thermal stability with minimal weight loss at 700 °C. The choice and no-choice bioassays confirmed strong repellent (80.97%) and antifeedant activity of PsAgNPs. Moreover, PsAgNPs exposure caused visible morphological changes in termites. Molecular docking simulation indicated possible attenuation of endoglucanase and bacteria-origin xylanase, digestive enzymes from termite gut, through partial blocking of the catalytic site by AgNPs. Altogether, our preliminary study suggests promising potentials of PsAgNPs for pest management in forestry and agriculture sectors to prevent damages to living trees, wood, crops, etc. As sustainable pest management practices demand low risk to the environment and biodiversity therefore, we recommend that more extensive studies should be performed to elucidate the environmental compatibility of PsAgNPs. |
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Interaction mechanism of plant-based nanoarchitectured materials with digestive enzymes of termites as target for pest control: Evidence from molecular docking simulation and in vitro studiesAgNPsEndoglucanaseMolecular dockingTermite controlXylanaseThe integration of nanotechnology for efficient pest management is gaining momentum to overcome the challenges and drawbacks of traditional approaches. However, studies pertaining to termite pest control using biosynthesized nanoparticles are seldom. The present study aims to highlight the following key points: a) green synthesis of AgNPs using Glochidion eriocarpum and their activity against wood-feeding termites, b) testing the hypothesis that AgNPs diminish digestive enzymes in termite gut through in silico analysis. The green synthesis route generated spherical PsAgNPs in the size range of 4-44.5 nm exhibiting higher thermal stability with minimal weight loss at 700 °C. The choice and no-choice bioassays confirmed strong repellent (80.97%) and antifeedant activity of PsAgNPs. Moreover, PsAgNPs exposure caused visible morphological changes in termites. Molecular docking simulation indicated possible attenuation of endoglucanase and bacteria-origin xylanase, digestive enzymes from termite gut, through partial blocking of the catalytic site by AgNPs. Altogether, our preliminary study suggests promising potentials of PsAgNPs for pest management in forestry and agriculture sectors to prevent damages to living trees, wood, crops, etc. As sustainable pest management practices demand low risk to the environment and biodiversity therefore, we recommend that more extensive studies should be performed to elucidate the environmental compatibility of PsAgNPs.China Postdoctoral Science FoundationNational Natural Science Foundation of ChinaCAS Key Laboratory of Tropical Forest Ecology Xishuangbanna Tropical Botanical Garden Chinese Academy of SciencesCenter of Plant Ecology Core Botanical Gardens Chinese Academy of SciencesDepartment of Pharmacology Institute of Biomedical Sciences University of São Paulo – USPSão Paulo State University (UNESP) Department of Physics and Chemistry School of EngineeringDepartment of Pharmacology School of Medical Science University of Campinas – UNICAMP, CampinasSão Paulo State University (UNESP) Department of Physics and Chemistry School of EngineeringChina Postdoctoral Science Foundation: 2018M631112National Natural Science Foundation of China: 31700457National Natural Science Foundation of China: 41877064Chinese Academy of SciencesUniversidade de São Paulo (USP)Universidade Estadual Paulista (Unesp)Universidade Estadual de Campinas (UNICAMP)Mishra, SandhyaWang, Wentingde Oliveira, Ivan PiresAtapattu, Anjana J.Xia, Shang-WenGrillo, Renato [UNESP]Lescano, Caroline HonaiserYang, Xiaodong2021-06-25T10:11:01Z2021-06-25T10:11:01Z2021-02-05info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.jhazmat.2020.123840Journal of Hazardous Materials, v. 403.1873-33360304-3894http://hdl.handle.net/11449/20517110.1016/j.jhazmat.2020.1238402-s2.0-85090597763Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Hazardous Materialsinfo:eu-repo/semantics/openAccess2021-10-23T11:21:24Zoai:repositorio.unesp.br:11449/205171Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T11:21:24Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Interaction mechanism of plant-based nanoarchitectured materials with digestive enzymes of termites as target for pest control: Evidence from molecular docking simulation and in vitro studies |
title |
Interaction mechanism of plant-based nanoarchitectured materials with digestive enzymes of termites as target for pest control: Evidence from molecular docking simulation and in vitro studies |
spellingShingle |
Interaction mechanism of plant-based nanoarchitectured materials with digestive enzymes of termites as target for pest control: Evidence from molecular docking simulation and in vitro studies Mishra, Sandhya AgNPs Endoglucanase Molecular docking Termite control Xylanase |
title_short |
Interaction mechanism of plant-based nanoarchitectured materials with digestive enzymes of termites as target for pest control: Evidence from molecular docking simulation and in vitro studies |
title_full |
Interaction mechanism of plant-based nanoarchitectured materials with digestive enzymes of termites as target for pest control: Evidence from molecular docking simulation and in vitro studies |
title_fullStr |
Interaction mechanism of plant-based nanoarchitectured materials with digestive enzymes of termites as target for pest control: Evidence from molecular docking simulation and in vitro studies |
title_full_unstemmed |
Interaction mechanism of plant-based nanoarchitectured materials with digestive enzymes of termites as target for pest control: Evidence from molecular docking simulation and in vitro studies |
title_sort |
Interaction mechanism of plant-based nanoarchitectured materials with digestive enzymes of termites as target for pest control: Evidence from molecular docking simulation and in vitro studies |
author |
Mishra, Sandhya |
author_facet |
Mishra, Sandhya Wang, Wenting de Oliveira, Ivan Pires Atapattu, Anjana J. Xia, Shang-Wen Grillo, Renato [UNESP] Lescano, Caroline Honaiser Yang, Xiaodong |
author_role |
author |
author2 |
Wang, Wenting de Oliveira, Ivan Pires Atapattu, Anjana J. Xia, Shang-Wen Grillo, Renato [UNESP] Lescano, Caroline Honaiser Yang, Xiaodong |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Chinese Academy of Sciences Universidade de São Paulo (USP) Universidade Estadual Paulista (Unesp) Universidade Estadual de Campinas (UNICAMP) |
dc.contributor.author.fl_str_mv |
Mishra, Sandhya Wang, Wenting de Oliveira, Ivan Pires Atapattu, Anjana J. Xia, Shang-Wen Grillo, Renato [UNESP] Lescano, Caroline Honaiser Yang, Xiaodong |
dc.subject.por.fl_str_mv |
AgNPs Endoglucanase Molecular docking Termite control Xylanase |
topic |
AgNPs Endoglucanase Molecular docking Termite control Xylanase |
description |
The integration of nanotechnology for efficient pest management is gaining momentum to overcome the challenges and drawbacks of traditional approaches. However, studies pertaining to termite pest control using biosynthesized nanoparticles are seldom. The present study aims to highlight the following key points: a) green synthesis of AgNPs using Glochidion eriocarpum and their activity against wood-feeding termites, b) testing the hypothesis that AgNPs diminish digestive enzymes in termite gut through in silico analysis. The green synthesis route generated spherical PsAgNPs in the size range of 4-44.5 nm exhibiting higher thermal stability with minimal weight loss at 700 °C. The choice and no-choice bioassays confirmed strong repellent (80.97%) and antifeedant activity of PsAgNPs. Moreover, PsAgNPs exposure caused visible morphological changes in termites. Molecular docking simulation indicated possible attenuation of endoglucanase and bacteria-origin xylanase, digestive enzymes from termite gut, through partial blocking of the catalytic site by AgNPs. Altogether, our preliminary study suggests promising potentials of PsAgNPs for pest management in forestry and agriculture sectors to prevent damages to living trees, wood, crops, etc. As sustainable pest management practices demand low risk to the environment and biodiversity therefore, we recommend that more extensive studies should be performed to elucidate the environmental compatibility of PsAgNPs. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-06-25T10:11:01Z 2021-06-25T10:11:01Z 2021-02-05 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.jhazmat.2020.123840 Journal of Hazardous Materials, v. 403. 1873-3336 0304-3894 http://hdl.handle.net/11449/205171 10.1016/j.jhazmat.2020.123840 2-s2.0-85090597763 |
url |
http://dx.doi.org/10.1016/j.jhazmat.2020.123840 http://hdl.handle.net/11449/205171 |
identifier_str_mv |
Journal of Hazardous Materials, v. 403. 1873-3336 0304-3894 10.1016/j.jhazmat.2020.123840 2-s2.0-85090597763 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Hazardous Materials |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1799964977498423296 |