Variation of Laser Intensity on the Healing of Cutaneous Wounds
Autor(a) principal: | |
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Data de Publicação: | 2003 |
Outros Autores: | , , |
Tipo de documento: | Artigo de conferência |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1117/12.472884 http://hdl.handle.net/11449/67419 |
Resumo: | Tissue repair is an integration of dynamic interactive processes that involves soluble mediators, blood components, production of extra-cellular matrix and mesenchymal cells. Many studies involving the use of LLLT shows that the healing process is favored by such therapy. The aim of this work was to evaluate, through histological analysis, the tissue effects of cutaneous wounds submitted to different intensities and a same irradiation dose with lasers in λ670 or λ685nm. Eighteen animals were divided in two experimental groups according to wavelength used (λ670 or λ685nm). Each one of these groups was divided still in three subgroups of three animals each, related to the intensity of applied irradiation (2, 15 or 25mW). Twelve animals acted as untreated controls and were not irradiated. The irradiation was carried out during seven days. The animals were sacrificed eight days after surgery. The specimens were removed, kept in 4% formaldehyde for 24 hours, routinely prepared to wax, stained with H&E and analyzed under light microscopy. The histological characteristics observed, so much in the irradiated animals, as in the control, they are indicative of a substitution repair process, however, the LLLT modulatory positive effect was observed, in the healing process, mainly associate to the use of the shorter wavelength and low power. The results of the present study indicate that LLLT improves cutaneous wound repair and best results are achieved when higher potencies associated to short wavelengths or lower potencies associated to higher wavelengths are used. |
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Variation of Laser Intensity on the Healing of Cutaneous WoundsLaser TherapyLLLTTissue repairWound HealingBloodDosimetryHistologyIrradiationLaser surgeryMonochromatorsOptical microscopyTissueCutaneous woundsLaser intensityLaser tissue interactionTissue repair is an integration of dynamic interactive processes that involves soluble mediators, blood components, production of extra-cellular matrix and mesenchymal cells. Many studies involving the use of LLLT shows that the healing process is favored by such therapy. The aim of this work was to evaluate, through histological analysis, the tissue effects of cutaneous wounds submitted to different intensities and a same irradiation dose with lasers in λ670 or λ685nm. Eighteen animals were divided in two experimental groups according to wavelength used (λ670 or λ685nm). Each one of these groups was divided still in three subgroups of three animals each, related to the intensity of applied irradiation (2, 15 or 25mW). Twelve animals acted as untreated controls and were not irradiated. The irradiation was carried out during seven days. The animals were sacrificed eight days after surgery. The specimens were removed, kept in 4% formaldehyde for 24 hours, routinely prepared to wax, stained with H&E and analyzed under light microscopy. The histological characteristics observed, so much in the irradiated animals, as in the control, they are indicative of a substitution repair process, however, the LLLT modulatory positive effect was observed, in the healing process, mainly associate to the use of the shorter wavelength and low power. The results of the present study indicate that LLLT improves cutaneous wound repair and best results are achieved when higher potencies associated to short wavelengths or lower potencies associated to higher wavelengths are used.School of Dentistry Univ. of the Vale do Paraíba, São José dos Campos, SPIP and D Vale do Paraíba University, São José dos Campos, SPLaser Center School of Dentistry Federal University of Bahia, Salvador, BahiaSchool of Dentistry UNESP, São José dos Campos, SPSchool of Dentistry UNESP, São José dos Campos, SPUniv. of the Vale do ParaíbaVale do Paraíba UniversityUniversidade Federal da Bahia (UFBA)Universidade Estadual Paulista (Unesp)Do Nascimento, Patrícia M.Pinheiro, Antonio Luiz B.Salgado, Miguel A.C. [UNESP]Ramalho, Luciana M. Pedreira2014-05-27T11:20:54Z2014-05-27T11:20:54Z2003-09-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/conferenceObject150-155http://dx.doi.org/10.1117/12.472884Proceedings of SPIE - The International Society for Optical Engineering, v. 4950, p. 150-155.0277-786Xhttp://hdl.handle.net/11449/6741910.1117/12.4728842-s2.0-0141524138Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengProceedings of SPIE - The International Society for Optical Engineeringinfo:eu-repo/semantics/openAccess2021-10-23T21:41:26Zoai:repositorio.unesp.br:11449/67419Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T21:41:26Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Variation of Laser Intensity on the Healing of Cutaneous Wounds |
title |
Variation of Laser Intensity on the Healing of Cutaneous Wounds |
spellingShingle |
Variation of Laser Intensity on the Healing of Cutaneous Wounds Do Nascimento, Patrícia M. Laser Therapy LLLT Tissue repair Wound Healing Blood Dosimetry Histology Irradiation Laser surgery Monochromators Optical microscopy Tissue Cutaneous wounds Laser intensity Laser tissue interaction |
title_short |
Variation of Laser Intensity on the Healing of Cutaneous Wounds |
title_full |
Variation of Laser Intensity on the Healing of Cutaneous Wounds |
title_fullStr |
Variation of Laser Intensity on the Healing of Cutaneous Wounds |
title_full_unstemmed |
Variation of Laser Intensity on the Healing of Cutaneous Wounds |
title_sort |
Variation of Laser Intensity on the Healing of Cutaneous Wounds |
author |
Do Nascimento, Patrícia M. |
author_facet |
Do Nascimento, Patrícia M. Pinheiro, Antonio Luiz B. Salgado, Miguel A.C. [UNESP] Ramalho, Luciana M. Pedreira |
author_role |
author |
author2 |
Pinheiro, Antonio Luiz B. Salgado, Miguel A.C. [UNESP] Ramalho, Luciana M. Pedreira |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Univ. of the Vale do Paraíba Vale do Paraíba University Universidade Federal da Bahia (UFBA) Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Do Nascimento, Patrícia M. Pinheiro, Antonio Luiz B. Salgado, Miguel A.C. [UNESP] Ramalho, Luciana M. Pedreira |
dc.subject.por.fl_str_mv |
Laser Therapy LLLT Tissue repair Wound Healing Blood Dosimetry Histology Irradiation Laser surgery Monochromators Optical microscopy Tissue Cutaneous wounds Laser intensity Laser tissue interaction |
topic |
Laser Therapy LLLT Tissue repair Wound Healing Blood Dosimetry Histology Irradiation Laser surgery Monochromators Optical microscopy Tissue Cutaneous wounds Laser intensity Laser tissue interaction |
description |
Tissue repair is an integration of dynamic interactive processes that involves soluble mediators, blood components, production of extra-cellular matrix and mesenchymal cells. Many studies involving the use of LLLT shows that the healing process is favored by such therapy. The aim of this work was to evaluate, through histological analysis, the tissue effects of cutaneous wounds submitted to different intensities and a same irradiation dose with lasers in λ670 or λ685nm. Eighteen animals were divided in two experimental groups according to wavelength used (λ670 or λ685nm). Each one of these groups was divided still in three subgroups of three animals each, related to the intensity of applied irradiation (2, 15 or 25mW). Twelve animals acted as untreated controls and were not irradiated. The irradiation was carried out during seven days. The animals were sacrificed eight days after surgery. The specimens were removed, kept in 4% formaldehyde for 24 hours, routinely prepared to wax, stained with H&E and analyzed under light microscopy. The histological characteristics observed, so much in the irradiated animals, as in the control, they are indicative of a substitution repair process, however, the LLLT modulatory positive effect was observed, in the healing process, mainly associate to the use of the shorter wavelength and low power. The results of the present study indicate that LLLT improves cutaneous wound repair and best results are achieved when higher potencies associated to short wavelengths or lower potencies associated to higher wavelengths are used. |
publishDate |
2003 |
dc.date.none.fl_str_mv |
2003-09-30 2014-05-27T11:20:54Z 2014-05-27T11:20:54Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/conferenceObject |
format |
conferenceObject |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1117/12.472884 Proceedings of SPIE - The International Society for Optical Engineering, v. 4950, p. 150-155. 0277-786X http://hdl.handle.net/11449/67419 10.1117/12.472884 2-s2.0-0141524138 |
url |
http://dx.doi.org/10.1117/12.472884 http://hdl.handle.net/11449/67419 |
identifier_str_mv |
Proceedings of SPIE - The International Society for Optical Engineering, v. 4950, p. 150-155. 0277-786X 10.1117/12.472884 2-s2.0-0141524138 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Proceedings of SPIE - The International Society for Optical Engineering |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
150-155 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1799964543184535552 |