Growth performance and intestinal replacement time of 13C in newly weaned piglets supplemented with nucleotides or glutamic acid
Main Author: | |
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Publication Date: | 2019 |
Other Authors: | , , , , , , , |
Format: | Article |
Language: | eng |
Source: | Repositório Institucional da UNESP |
Download full: | http://dx.doi.org/10.1016/j.livsci.2019.07.008 http://hdl.handle.net/11449/187870 |
Summary: | Dietary supplementation of nucleotides (NU) and glutamic acid (GA) have been suggested for post-weaned pigs because of their potential role as performance enhancers. During this phase, both additives may become essential for newly weaned piglets acting mainly for energy generation and forming molecular basis that are important for intestinal renewal. Two experiments were conducted to evaluate the effects of dietary NU and GA on growth performance and intestinal replacement time of 13C in weaned piglets. In both experiments pigs were assigned to treatments in a 2 × 2 factorial arrangement, based on two levels of NU (0 and 0.1%) and two levels of GA (0 and 1%). The energy source of the maternal diet was based on corn (rich in 13C) whereas piglets’ post-weaning diets were based on rice (poor in 13C). In the first experiment, 84 piglets were weaned at 21 days of age and growth performance was monitored during three experimental phases (0–15d, 16–27d and 28–35d). In the second experiment, in order to assess the intestinal replacement time of 13C in weaned piglets, the differences between the natural 13C abundance in maternal diet and piglets post-weaning diets were used. At day 0 (weaning), three piglets were slaughtered and used as an initial 13C ratio for duodenum and jejunum. At days 3, 6, 9, 14, 21, 34 and 49, three more piglets by treatment were slaughtered. Exponential regression analysis from each treatment was used to determine the incorporation of 13C in small intestine tissues between supplemented and control groups (without NU and GA) to determine the 13C replacement time. In the first study, dietary NU improved G:F (p < 0.05) from day 28–35, whereas dietary GA improved G:F (p < 0.05) from day 0–15, day 28–35 and for the overall experimental period (day 0–35). In the second study, NU supplementation and the interaction of NU × GA improved the replacement time of 13C in the duodenum mucosa (21.12 ± 2.14 days and 21.85 ± 2.13 days, respectively) compared to control (24.95 days). The use of dietary NU and GA during the post-weaning period improves performance but only NU accelerates the replacement time of 13C on duodenal mucosa during the post-weaning period in pigs. |
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Growth performance and intestinal replacement time of 13C in newly weaned piglets supplemented with nucleotides or glutamic acidGlutamateIsotopesNucleotidesPigletsReplacement of 13CDietary supplementation of nucleotides (NU) and glutamic acid (GA) have been suggested for post-weaned pigs because of their potential role as performance enhancers. During this phase, both additives may become essential for newly weaned piglets acting mainly for energy generation and forming molecular basis that are important for intestinal renewal. Two experiments were conducted to evaluate the effects of dietary NU and GA on growth performance and intestinal replacement time of 13C in weaned piglets. In both experiments pigs were assigned to treatments in a 2 × 2 factorial arrangement, based on two levels of NU (0 and 0.1%) and two levels of GA (0 and 1%). The energy source of the maternal diet was based on corn (rich in 13C) whereas piglets’ post-weaning diets were based on rice (poor in 13C). In the first experiment, 84 piglets were weaned at 21 days of age and growth performance was monitored during three experimental phases (0–15d, 16–27d and 28–35d). In the second experiment, in order to assess the intestinal replacement time of 13C in weaned piglets, the differences between the natural 13C abundance in maternal diet and piglets post-weaning diets were used. At day 0 (weaning), three piglets were slaughtered and used as an initial 13C ratio for duodenum and jejunum. At days 3, 6, 9, 14, 21, 34 and 49, three more piglets by treatment were slaughtered. Exponential regression analysis from each treatment was used to determine the incorporation of 13C in small intestine tissues between supplemented and control groups (without NU and GA) to determine the 13C replacement time. In the first study, dietary NU improved G:F (p < 0.05) from day 28–35, whereas dietary GA improved G:F (p < 0.05) from day 0–15, day 28–35 and for the overall experimental period (day 0–35). In the second study, NU supplementation and the interaction of NU × GA improved the replacement time of 13C in the duodenum mucosa (21.12 ± 2.14 days and 21.85 ± 2.13 days, respectively) compared to control (24.95 days). The use of dietary NU and GA during the post-weaning period improves performance but only NU accelerates the replacement time of 13C on duodenal mucosa during the post-weaning period in pigs.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)São Paulo State University (UNESP) School of Veterinary Medicine and Animal ScienceUniversity of São Paulo (USP) School of Veterinary Medicine and Animal ScienceUniversidade Federal da Grande Dourados (UFGD) School of Agriculture, DouradosSherbrooke Research and Development Centre Agriculture and Agri-Food CanadaSão Paulo State University (UNESP) School of Veterinary Medicine and Animal ScienceFAPESP: 2013/18619-7FAPESP: 2013/25616-4Universidade Estadual Paulista (Unesp)Universidade de São Paulo (USP)School of AgricultureAgriculture and Agri-Food CanadaSantos, L. S. [UNESP]Miassi, G. M. [UNESP]Tse, M. L.P. [UNESP]Gomes, L. M. [UNESP]Berto, P. N.Denadai, J. C. [UNESP]Caldara, F. R.Dalto, D. B.Berto, D. A. [UNESP]2019-10-06T15:49:49Z2019-10-06T15:49:49Z2019-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article160-165http://dx.doi.org/10.1016/j.livsci.2019.07.008Livestock Science, v. 227, p. 160-165.1871-1413http://hdl.handle.net/11449/18787010.1016/j.livsci.2019.07.0082-s2.0-85068981060Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengLivestock Scienceinfo:eu-repo/semantics/openAccess2021-10-23T20:19:29Zoai:repositorio.unesp.br:11449/187870Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T20:19:29Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Growth performance and intestinal replacement time of 13C in newly weaned piglets supplemented with nucleotides or glutamic acid |
title |
Growth performance and intestinal replacement time of 13C in newly weaned piglets supplemented with nucleotides or glutamic acid |
spellingShingle |
Growth performance and intestinal replacement time of 13C in newly weaned piglets supplemented with nucleotides or glutamic acid Santos, L. S. [UNESP] Glutamate Isotopes Nucleotides Piglets Replacement of 13C |
title_short |
Growth performance and intestinal replacement time of 13C in newly weaned piglets supplemented with nucleotides or glutamic acid |
title_full |
Growth performance and intestinal replacement time of 13C in newly weaned piglets supplemented with nucleotides or glutamic acid |
title_fullStr |
Growth performance and intestinal replacement time of 13C in newly weaned piglets supplemented with nucleotides or glutamic acid |
title_full_unstemmed |
Growth performance and intestinal replacement time of 13C in newly weaned piglets supplemented with nucleotides or glutamic acid |
title_sort |
Growth performance and intestinal replacement time of 13C in newly weaned piglets supplemented with nucleotides or glutamic acid |
author |
Santos, L. S. [UNESP] |
author_facet |
Santos, L. S. [UNESP] Miassi, G. M. [UNESP] Tse, M. L.P. [UNESP] Gomes, L. M. [UNESP] Berto, P. N. Denadai, J. C. [UNESP] Caldara, F. R. Dalto, D. B. Berto, D. A. [UNESP] |
author_role |
author |
author2 |
Miassi, G. M. [UNESP] Tse, M. L.P. [UNESP] Gomes, L. M. [UNESP] Berto, P. N. Denadai, J. C. [UNESP] Caldara, F. R. Dalto, D. B. Berto, D. A. [UNESP] |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade de São Paulo (USP) School of Agriculture Agriculture and Agri-Food Canada |
dc.contributor.author.fl_str_mv |
Santos, L. S. [UNESP] Miassi, G. M. [UNESP] Tse, M. L.P. [UNESP] Gomes, L. M. [UNESP] Berto, P. N. Denadai, J. C. [UNESP] Caldara, F. R. Dalto, D. B. Berto, D. A. [UNESP] |
dc.subject.por.fl_str_mv |
Glutamate Isotopes Nucleotides Piglets Replacement of 13C |
topic |
Glutamate Isotopes Nucleotides Piglets Replacement of 13C |
description |
Dietary supplementation of nucleotides (NU) and glutamic acid (GA) have been suggested for post-weaned pigs because of their potential role as performance enhancers. During this phase, both additives may become essential for newly weaned piglets acting mainly for energy generation and forming molecular basis that are important for intestinal renewal. Two experiments were conducted to evaluate the effects of dietary NU and GA on growth performance and intestinal replacement time of 13C in weaned piglets. In both experiments pigs were assigned to treatments in a 2 × 2 factorial arrangement, based on two levels of NU (0 and 0.1%) and two levels of GA (0 and 1%). The energy source of the maternal diet was based on corn (rich in 13C) whereas piglets’ post-weaning diets were based on rice (poor in 13C). In the first experiment, 84 piglets were weaned at 21 days of age and growth performance was monitored during three experimental phases (0–15d, 16–27d and 28–35d). In the second experiment, in order to assess the intestinal replacement time of 13C in weaned piglets, the differences between the natural 13C abundance in maternal diet and piglets post-weaning diets were used. At day 0 (weaning), three piglets were slaughtered and used as an initial 13C ratio for duodenum and jejunum. At days 3, 6, 9, 14, 21, 34 and 49, three more piglets by treatment were slaughtered. Exponential regression analysis from each treatment was used to determine the incorporation of 13C in small intestine tissues between supplemented and control groups (without NU and GA) to determine the 13C replacement time. In the first study, dietary NU improved G:F (p < 0.05) from day 28–35, whereas dietary GA improved G:F (p < 0.05) from day 0–15, day 28–35 and for the overall experimental period (day 0–35). In the second study, NU supplementation and the interaction of NU × GA improved the replacement time of 13C in the duodenum mucosa (21.12 ± 2.14 days and 21.85 ± 2.13 days, respectively) compared to control (24.95 days). The use of dietary NU and GA during the post-weaning period improves performance but only NU accelerates the replacement time of 13C on duodenal mucosa during the post-weaning period in pigs. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-10-06T15:49:49Z 2019-10-06T15:49:49Z 2019-09-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.livsci.2019.07.008 Livestock Science, v. 227, p. 160-165. 1871-1413 http://hdl.handle.net/11449/187870 10.1016/j.livsci.2019.07.008 2-s2.0-85068981060 |
url |
http://dx.doi.org/10.1016/j.livsci.2019.07.008 http://hdl.handle.net/11449/187870 |
identifier_str_mv |
Livestock Science, v. 227, p. 160-165. 1871-1413 10.1016/j.livsci.2019.07.008 2-s2.0-85068981060 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Livestock Science |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
160-165 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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1797789414961709056 |