Mycogenic metal nanoparticles for the treatment of mycobacterioses
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3390/antibiotics9090569 http://hdl.handle.net/11449/199361 |
Resumo: | Mycobacterial infections are a resurgent and increasingly relevant problem. Within these, tuberculosis (TB) is particularly worrying as it is one of the top ten causes of death in the world and is the infectious disease that causes the highest number of deaths. A further concern is the on-going emergence of antimicrobial resistance, which seriously limits treatment. The COVID-19 pandemic has worsened current circumstances and future infections will be more incident. It is urgent to plan, draw solutions, and act to mitigate these issues, namely by exploring new approaches. The aims of this review are to showcase the extensive research and application of silver nanoparticles (AgNPs) and other metal nanoparticles (MNPs) as antimicrobial agents. We highlight the advantages of mycogenic synthesis, and report on their underexplored potential as agents in the fight against all mycobacterioses (non-tuberculous mycobacterial infections as well as TB). We propose further exploration of this field. |
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Repositório Institucional da UNESP |
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Mycogenic metal nanoparticles for the treatment of mycobacteriosesFilamentous fungiMetal nanoparticles (MNP)Mycobacterium tuberculosis (MTb)Mycogenic synthesisNontuberculous mycobacteria (NTM)Silver nanoparticles (AgNP)Tuberculosis (TB)Mycobacterial infections are a resurgent and increasingly relevant problem. Within these, tuberculosis (TB) is particularly worrying as it is one of the top ten causes of death in the world and is the infectious disease that causes the highest number of deaths. A further concern is the on-going emergence of antimicrobial resistance, which seriously limits treatment. The COVID-19 pandemic has worsened current circumstances and future infections will be more incident. It is urgent to plan, draw solutions, and act to mitigate these issues, namely by exploring new approaches. The aims of this review are to showcase the extensive research and application of silver nanoparticles (AgNPs) and other metal nanoparticles (MNPs) as antimicrobial agents. We highlight the advantages of mycogenic synthesis, and report on their underexplored potential as agents in the fight against all mycobacterioses (non-tuberculous mycobacterial infections as well as TB). We propose further exploration of this field.State Key Laboratory of Lunar and Planetary Sciences Macau University of Science and Technology, Avenida Wai LongBioscience Institute São Paulo State University (UNESP)Bioscience Institute São Paulo State University (UNESP)Macau University of Science and TechnologyUniversidade Estadual Paulista (Unesp)Simões, Marta FilipaOttoni, Cristiane Angélica [UNESP]Antunes, André2020-12-12T01:37:43Z2020-12-12T01:37:43Z2020-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1-21http://dx.doi.org/10.3390/antibiotics9090569Antibiotics, v. 9, n. 9, p. 1-21, 2020.2079-6382http://hdl.handle.net/11449/19936110.3390/antibiotics90905692-s2.0-8509053663896201224557082230000-0003-4069-509XScopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengAntibioticsinfo:eu-repo/semantics/openAccess2022-03-09T00:16:17Zoai:repositorio.unesp.br:11449/199361Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-03-09T00:16:17Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Mycogenic metal nanoparticles for the treatment of mycobacterioses |
title |
Mycogenic metal nanoparticles for the treatment of mycobacterioses |
spellingShingle |
Mycogenic metal nanoparticles for the treatment of mycobacterioses Simões, Marta Filipa Filamentous fungi Metal nanoparticles (MNP) Mycobacterium tuberculosis (MTb) Mycogenic synthesis Nontuberculous mycobacteria (NTM) Silver nanoparticles (AgNP) Tuberculosis (TB) |
title_short |
Mycogenic metal nanoparticles for the treatment of mycobacterioses |
title_full |
Mycogenic metal nanoparticles for the treatment of mycobacterioses |
title_fullStr |
Mycogenic metal nanoparticles for the treatment of mycobacterioses |
title_full_unstemmed |
Mycogenic metal nanoparticles for the treatment of mycobacterioses |
title_sort |
Mycogenic metal nanoparticles for the treatment of mycobacterioses |
author |
Simões, Marta Filipa |
author_facet |
Simões, Marta Filipa Ottoni, Cristiane Angélica [UNESP] Antunes, André |
author_role |
author |
author2 |
Ottoni, Cristiane Angélica [UNESP] Antunes, André |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Macau University of Science and Technology Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Simões, Marta Filipa Ottoni, Cristiane Angélica [UNESP] Antunes, André |
dc.subject.por.fl_str_mv |
Filamentous fungi Metal nanoparticles (MNP) Mycobacterium tuberculosis (MTb) Mycogenic synthesis Nontuberculous mycobacteria (NTM) Silver nanoparticles (AgNP) Tuberculosis (TB) |
topic |
Filamentous fungi Metal nanoparticles (MNP) Mycobacterium tuberculosis (MTb) Mycogenic synthesis Nontuberculous mycobacteria (NTM) Silver nanoparticles (AgNP) Tuberculosis (TB) |
description |
Mycobacterial infections are a resurgent and increasingly relevant problem. Within these, tuberculosis (TB) is particularly worrying as it is one of the top ten causes of death in the world and is the infectious disease that causes the highest number of deaths. A further concern is the on-going emergence of antimicrobial resistance, which seriously limits treatment. The COVID-19 pandemic has worsened current circumstances and future infections will be more incident. It is urgent to plan, draw solutions, and act to mitigate these issues, namely by exploring new approaches. The aims of this review are to showcase the extensive research and application of silver nanoparticles (AgNPs) and other metal nanoparticles (MNPs) as antimicrobial agents. We highlight the advantages of mycogenic synthesis, and report on their underexplored potential as agents in the fight against all mycobacterioses (non-tuberculous mycobacterial infections as well as TB). We propose further exploration of this field. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-12T01:37:43Z 2020-12-12T01:37:43Z 2020-09-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3390/antibiotics9090569 Antibiotics, v. 9, n. 9, p. 1-21, 2020. 2079-6382 http://hdl.handle.net/11449/199361 10.3390/antibiotics9090569 2-s2.0-85090536638 9620122455708223 0000-0003-4069-509X |
url |
http://dx.doi.org/10.3390/antibiotics9090569 http://hdl.handle.net/11449/199361 |
identifier_str_mv |
Antibiotics, v. 9, n. 9, p. 1-21, 2020. 2079-6382 10.3390/antibiotics9090569 2-s2.0-85090536638 9620122455708223 0000-0003-4069-509X |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Antibiotics |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
1-21 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1797789531978596352 |