DNA-damaging activity of a cinnamate derivative and further compounds from Cinnamomum Australe (Lauraceae)

Detalhes bibliográficos
Autor(a) principal: Carbonezi, C. A.
Data de Publicação: 2004
Outros Autores: Lopes, M. N., Silva, DHS, Araujo, A. R., Bolzani, V. D., Young, MCM, Silva, M. R. da
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://hdl.handle.net/11449/194626
Resumo: The bioactive compound traps-3'-methylsulphonylallyl traps-cinnamate (1) along with the inactives iryelliptin (2) and (7R,8S,1'S)-Delta8-3',5'-dimethoxy-1',4'-dihydro-4'-oxo-7.0.2',8.1'-neolignan (3) were isolated from the leaves of Cinnamomum australe. The structures of these compounds were assigned by analysis of 1D and 2D NMR data and comparison with data registered in the literature for these compounds. The DNA-damaging activity of 1 is being described for the first time.
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spelling DNA-damaging activity of a cinnamate derivative and further compounds from Cinnamomum Australe (Lauraceae)Cinnamomum australeLauraceaeDNA-damaging activityThe bioactive compound traps-3'-methylsulphonylallyl traps-cinnamate (1) along with the inactives iryelliptin (2) and (7R,8S,1'S)-Delta8-3',5'-dimethoxy-1',4'-dihydro-4'-oxo-7.0.2',8.1'-neolignan (3) were isolated from the leaves of Cinnamomum australe. The structures of these compounds were assigned by analysis of 1D and 2D NMR data and comparison with data registered in the literature for these compounds. The DNA-damaging activity of 1 is being described for the first time.Univ Estadual Paulista, Inst Quim, BR-14801970 Araraquara, SP, BrazilInst Bot, Seccao Fisiol & Bioquim Plantas, BR-01061970 Sao Paulo, BrazilUniv Estadual Paulista, Inst Quim, BR-14801970 Araraquara, SP, BrazilSoc Brasileira QuimicaUniversidade Estadual Paulista (Unesp)Inst BotCarbonezi, C. A.Lopes, M. N.Silva, DHSAraujo, A. R.Bolzani, V. D.Young, MCMSilva, M. R. da2020-12-10T16:32:11Z2020-12-10T16:32:11Z2004-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article196-198Quimica Nova. Sao Paulo: Soc Brasileira Quimica, v. 27, n. 2, p. 196-198, 2004.0100-4042http://hdl.handle.net/11449/194626WOS:000220424900005Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporQuimica Novainfo:eu-repo/semantics/openAccess2021-10-22T19:03:26Zoai:repositorio.unesp.br:11449/194626Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-22T19:03:26Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv DNA-damaging activity of a cinnamate derivative and further compounds from Cinnamomum Australe (Lauraceae)
title DNA-damaging activity of a cinnamate derivative and further compounds from Cinnamomum Australe (Lauraceae)
spellingShingle DNA-damaging activity of a cinnamate derivative and further compounds from Cinnamomum Australe (Lauraceae)
Carbonezi, C. A.
Cinnamomum australe
Lauraceae
DNA-damaging activity
title_short DNA-damaging activity of a cinnamate derivative and further compounds from Cinnamomum Australe (Lauraceae)
title_full DNA-damaging activity of a cinnamate derivative and further compounds from Cinnamomum Australe (Lauraceae)
title_fullStr DNA-damaging activity of a cinnamate derivative and further compounds from Cinnamomum Australe (Lauraceae)
title_full_unstemmed DNA-damaging activity of a cinnamate derivative and further compounds from Cinnamomum Australe (Lauraceae)
title_sort DNA-damaging activity of a cinnamate derivative and further compounds from Cinnamomum Australe (Lauraceae)
author Carbonezi, C. A.
author_facet Carbonezi, C. A.
Lopes, M. N.
Silva, DHS
Araujo, A. R.
Bolzani, V. D.
Young, MCM
Silva, M. R. da
author_role author
author2 Lopes, M. N.
Silva, DHS
Araujo, A. R.
Bolzani, V. D.
Young, MCM
Silva, M. R. da
author2_role author
author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
Inst Bot
dc.contributor.author.fl_str_mv Carbonezi, C. A.
Lopes, M. N.
Silva, DHS
Araujo, A. R.
Bolzani, V. D.
Young, MCM
Silva, M. R. da
dc.subject.por.fl_str_mv Cinnamomum australe
Lauraceae
DNA-damaging activity
topic Cinnamomum australe
Lauraceae
DNA-damaging activity
description The bioactive compound traps-3'-methylsulphonylallyl traps-cinnamate (1) along with the inactives iryelliptin (2) and (7R,8S,1'S)-Delta8-3',5'-dimethoxy-1',4'-dihydro-4'-oxo-7.0.2',8.1'-neolignan (3) were isolated from the leaves of Cinnamomum australe. The structures of these compounds were assigned by analysis of 1D and 2D NMR data and comparison with data registered in the literature for these compounds. The DNA-damaging activity of 1 is being described for the first time.
publishDate 2004
dc.date.none.fl_str_mv 2004-03-01
2020-12-10T16:32:11Z
2020-12-10T16:32:11Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv Quimica Nova. Sao Paulo: Soc Brasileira Quimica, v. 27, n. 2, p. 196-198, 2004.
0100-4042
http://hdl.handle.net/11449/194626
WOS:000220424900005
identifier_str_mv Quimica Nova. Sao Paulo: Soc Brasileira Quimica, v. 27, n. 2, p. 196-198, 2004.
0100-4042
WOS:000220424900005
url http://hdl.handle.net/11449/194626
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Quimica Nova
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 196-198
dc.publisher.none.fl_str_mv Soc Brasileira Quimica
publisher.none.fl_str_mv Soc Brasileira Quimica
dc.source.none.fl_str_mv Web of Science
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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