Galleria mellonella as a model host for human pathogens: Recent studies and new perspectives

Detalhes bibliográficos
Autor(a) principal: Junqueira, Juliana Campos [UNESP]
Data de Publicação: 2012
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.4161/viru.22493
http://hdl.handle.net/11449/227051
Resumo: The number of studies using G. mellonella as a model host for human pathogens has increased significantly in the last few years. Important studies were published from different countries for evaluating the pathogenesis of bacterial and fungal infections and for exploring the host defenses against pathogens. Therefore, standardized conditions for the use of G. melonella larvae need to be established. Recent research showed that the deprivation of G. mellonella larvae of food during the experiment caused a reduction in immune responses and an increased susceptibility to infection, suggesting that incubating of larvae in the presence or absence of nutrition may affect the results and comparisons among different laboratories. © 2012 Landes Bioscience.
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spelling Galleria mellonella as a model host for human pathogens: Recent studies and new perspectivesBacterial pathogenesisFungal pathogenesisGalleria mellonellaInfectionInvertebrate modelsThe number of studies using G. mellonella as a model host for human pathogens has increased significantly in the last few years. Important studies were published from different countries for evaluating the pathogenesis of bacterial and fungal infections and for exploring the host defenses against pathogens. Therefore, standardized conditions for the use of G. melonella larvae need to be established. Recent research showed that the deprivation of G. mellonella larvae of food during the experiment caused a reduction in immune responses and an increased susceptibility to infection, suggesting that incubating of larvae in the presence or absence of nutrition may affect the results and comparisons among different laboratories. © 2012 Landes Bioscience.Department of Biosciences and Oral Diagnosis São José dos Campos Dental School Universidade Estadual Paulista/UNESP, São PauloDepartment of Biosciences and Oral Diagnosis São José dos Campos Dental School Universidade Estadual Paulista/UNESP, São PauloUniversidade Estadual Paulista (UNESP)Junqueira, Juliana Campos [UNESP]2022-04-29T06:01:27Z2022-04-29T06:01:27Z2012-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.4161/viru.22493Virulence, v. 3, n. 6, 2012.2150-56082150-5594http://hdl.handle.net/11449/22705110.4161/viru.224932-s2.0-84870523148Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengVirulenceinfo:eu-repo/semantics/openAccess2022-04-29T06:01:27Zoai:repositorio.unesp.br:11449/227051Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-04-29T06:01:27Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Galleria mellonella as a model host for human pathogens: Recent studies and new perspectives
title Galleria mellonella as a model host for human pathogens: Recent studies and new perspectives
spellingShingle Galleria mellonella as a model host for human pathogens: Recent studies and new perspectives
Junqueira, Juliana Campos [UNESP]
Bacterial pathogenesis
Fungal pathogenesis
Galleria mellonella
Infection
Invertebrate models
title_short Galleria mellonella as a model host for human pathogens: Recent studies and new perspectives
title_full Galleria mellonella as a model host for human pathogens: Recent studies and new perspectives
title_fullStr Galleria mellonella as a model host for human pathogens: Recent studies and new perspectives
title_full_unstemmed Galleria mellonella as a model host for human pathogens: Recent studies and new perspectives
title_sort Galleria mellonella as a model host for human pathogens: Recent studies and new perspectives
author Junqueira, Juliana Campos [UNESP]
author_facet Junqueira, Juliana Campos [UNESP]
author_role author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
dc.contributor.author.fl_str_mv Junqueira, Juliana Campos [UNESP]
dc.subject.por.fl_str_mv Bacterial pathogenesis
Fungal pathogenesis
Galleria mellonella
Infection
Invertebrate models
topic Bacterial pathogenesis
Fungal pathogenesis
Galleria mellonella
Infection
Invertebrate models
description The number of studies using G. mellonella as a model host for human pathogens has increased significantly in the last few years. Important studies were published from different countries for evaluating the pathogenesis of bacterial and fungal infections and for exploring the host defenses against pathogens. Therefore, standardized conditions for the use of G. melonella larvae need to be established. Recent research showed that the deprivation of G. mellonella larvae of food during the experiment caused a reduction in immune responses and an increased susceptibility to infection, suggesting that incubating of larvae in the presence or absence of nutrition may affect the results and comparisons among different laboratories. © 2012 Landes Bioscience.
publishDate 2012
dc.date.none.fl_str_mv 2012-01-01
2022-04-29T06:01:27Z
2022-04-29T06:01:27Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.4161/viru.22493
Virulence, v. 3, n. 6, 2012.
2150-5608
2150-5594
http://hdl.handle.net/11449/227051
10.4161/viru.22493
2-s2.0-84870523148
url http://dx.doi.org/10.4161/viru.22493
http://hdl.handle.net/11449/227051
identifier_str_mv Virulence, v. 3, n. 6, 2012.
2150-5608
2150-5594
10.4161/viru.22493
2-s2.0-84870523148
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Virulence
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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