Antimicrobial action of four herbal plants over mixed-species biofilms of Candida albicans with four different microorganisms

• Autor(a) principal: Domingues, Nádia [UNESP]
• Data de Publicação: 2022
• Outros Autores: Ramos, Lucas de Paula [UNESP], Pereira, Larissa Marques [UNESP], do Rosário Estevam dos Santos, Pâmela Beatriz [UNESP], Scorzoni, Liliana [UNESP], Pereira, Thaís Cristine [UNESP], Abu Hasna, Amjad [UNESP], Carvalho, Cláudio Antonio Talge [UNESP], de Oliveira, Luciane Dias [UNESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.1111/aej.12681; http://hdl.handle.net/11449/242244
• topic: biofilm: Candida albicans; Enterococcus faecalis; Pseudomonas aeruginosa; Staphylococcus aureus; Streptococcus mutans

This study aimed to evaluate the antimicrobial effect of four herbal plants glycolic extracts over mixed-species biofilm composed of Candida albicans (C. albicans) and another pathogenic bacterium as alternative therapy to be investigated. Four plants extract of Pfaffia paniculata roots; Hamamelis virginiana leaf, Stryphnodendron barbatiman tree bark and Gymnema sylvestre stem and leaves were tested over multi-species biofilm of C. albicans (ATCC 18804) and Streptococcus mutans (ATCC 35688), Staphylococcus aureus (ATCC 6538), Enterococcus faecalis (ATCC 4083) or Pseudomonas aeruginosa (ATCC 15442) for 5 min and 24 h and colony forming units per millilitre was calculated. The data were analysed using Kruskal–Wallis with Dunn's test (p ≤ 0.05). All tested extracts showed antimicrobial action over the mixed-species biofilms after 24 h. Some extracts eliminated totally the biofilms. The glycolic extract of P. paniculata, H. virginiana, S. barbatiman and G. sylvestre are effective over mixed-species biofilms and may be indicated as endodontic irrigant or intracanal medication.