The Developing Left Superior Cervical Ganglion of Pacas (Agouti Paca)
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1002/ar.20918 http://hdl.handle.net/11449/2819 |
Resumo: | In this study the main question investigated was the number and size of both binucleate and mononucleate superior cervical ganglion (SCG) neurons and, whether post-natal development would affect these parameters. Twenty left SCGs from 20 male pacas were used. Four different ages were investigated, that is newborn (4 days), young (45 days), adult (2 years), and aged animals (7 years). By using design-based stereo-logical methods, that is the Cavalieri principle and a physical disector combined with serial sectioning, the total volume of ganglion and total number of mononucleate and binucleate neurons were estimated. Furthermore, the mean perikaryal (somal) volume of mononucleate and binucleate neurons was estimated using the vertical nucleator. The main findings of this study were a 154% increase in the SCG volume, a 95% increase in the total number of mononucleate SCG neurons and a 50% increase in the total volume of SCG neurons. In conclusion, apart from neuron number, different adaptive mechanisms may coexist in the autonomic nervous system to guarantee a functional homeostasis during ageing, which is not always associated with neuron losses. Anat Rec, 292:966-975, 2009. (C) 2009 Wiley-Liss, Inc. |
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The Developing Left Superior Cervical Ganglion of Pacas (Agouti Paca)SCGStereologyphysical disectorageingPacasIn this study the main question investigated was the number and size of both binucleate and mononucleate superior cervical ganglion (SCG) neurons and, whether post-natal development would affect these parameters. Twenty left SCGs from 20 male pacas were used. Four different ages were investigated, that is newborn (4 days), young (45 days), adult (2 years), and aged animals (7 years). By using design-based stereo-logical methods, that is the Cavalieri principle and a physical disector combined with serial sectioning, the total volume of ganglion and total number of mononucleate and binucleate neurons were estimated. Furthermore, the mean perikaryal (somal) volume of mononucleate and binucleate neurons was estimated using the vertical nucleator. The main findings of this study were a 154% increase in the SCG volume, a 95% increase in the total number of mononucleate SCG neurons and a 50% increase in the total volume of SCG neurons. In conclusion, apart from neuron number, different adaptive mechanisms may coexist in the autonomic nervous system to guarantee a functional homeostasis during ageing, which is not always associated with neuron losses. Anat Rec, 292:966-975, 2009. (C) 2009 Wiley-Liss, Inc.Univ São Paulo, Coll Vet Med, Dept Surg, LSSCA, BR-05508270 São Paulo, BrazilUniv Aarhus, Stereol & Elect Microscopy Res Lab, DK-8000 Aarhus, DenmarkUniv Aarhus, Mind Ctr, DK-8000 Aarhus, DenmarkSão Paulo State Univ UNESP, Coll Vet Med, Dept Morphol & Physiol, Jaboticabal, SP, BrazilUniv São Paulo, Inst Math & Stat, Dept Stat, BR-05508270 São Paulo, BrazilSão Paulo State Univ UNESP, Coll Vet Med, Dept Morphol & Physiol, Jaboticabal, SP, BrazilWiley-lissUniversidade de São Paulo (USP)Univ AarhusUniversidade Estadual Paulista (Unesp)Melo, Samanta RiosNyengaard, Jens RandelOliveira, Felipe da RozaLobo Ladd, Fernando VagnerBigaram Abrahao, Luciana MariaMachado, Marcia R. F. [UNESP]Sasahara, Tais H. C.De Melo, Mariana PereiraRibeiro, Antonio Augusto C. M.2014-05-20T13:15:47Z2014-05-20T13:15:47Z2009-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article966-975http://dx.doi.org/10.1002/ar.20918Anatomical Record-advances In Integrative Anatomy and Evolutionary Biology. Hoboken: Wiley-liss, v. 292, n. 7, p. 966-975, 2009.1932-8486http://hdl.handle.net/11449/281910.1002/ar.20918WOS:000267716200007Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengAnatomical Record-advances In Integrative Anatomy and Evolutionary Biology1.3730,766info:eu-repo/semantics/openAccess2021-10-23T11:21:53Zoai:repositorio.unesp.br:11449/2819Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T11:21:53Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
The Developing Left Superior Cervical Ganglion of Pacas (Agouti Paca) |
title |
The Developing Left Superior Cervical Ganglion of Pacas (Agouti Paca) |
spellingShingle |
The Developing Left Superior Cervical Ganglion of Pacas (Agouti Paca) Melo, Samanta Rios SCG Stereology physical disector ageing Pacas |
title_short |
The Developing Left Superior Cervical Ganglion of Pacas (Agouti Paca) |
title_full |
The Developing Left Superior Cervical Ganglion of Pacas (Agouti Paca) |
title_fullStr |
The Developing Left Superior Cervical Ganglion of Pacas (Agouti Paca) |
title_full_unstemmed |
The Developing Left Superior Cervical Ganglion of Pacas (Agouti Paca) |
title_sort |
The Developing Left Superior Cervical Ganglion of Pacas (Agouti Paca) |
author |
Melo, Samanta Rios |
author_facet |
Melo, Samanta Rios Nyengaard, Jens Randel Oliveira, Felipe da Roza Lobo Ladd, Fernando Vagner Bigaram Abrahao, Luciana Maria Machado, Marcia R. F. [UNESP] Sasahara, Tais H. C. De Melo, Mariana Pereira Ribeiro, Antonio Augusto C. M. |
author_role |
author |
author2 |
Nyengaard, Jens Randel Oliveira, Felipe da Roza Lobo Ladd, Fernando Vagner Bigaram Abrahao, Luciana Maria Machado, Marcia R. F. [UNESP] Sasahara, Tais H. C. De Melo, Mariana Pereira Ribeiro, Antonio Augusto C. M. |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) Univ Aarhus Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Melo, Samanta Rios Nyengaard, Jens Randel Oliveira, Felipe da Roza Lobo Ladd, Fernando Vagner Bigaram Abrahao, Luciana Maria Machado, Marcia R. F. [UNESP] Sasahara, Tais H. C. De Melo, Mariana Pereira Ribeiro, Antonio Augusto C. M. |
dc.subject.por.fl_str_mv |
SCG Stereology physical disector ageing Pacas |
topic |
SCG Stereology physical disector ageing Pacas |
description |
In this study the main question investigated was the number and size of both binucleate and mononucleate superior cervical ganglion (SCG) neurons and, whether post-natal development would affect these parameters. Twenty left SCGs from 20 male pacas were used. Four different ages were investigated, that is newborn (4 days), young (45 days), adult (2 years), and aged animals (7 years). By using design-based stereo-logical methods, that is the Cavalieri principle and a physical disector combined with serial sectioning, the total volume of ganglion and total number of mononucleate and binucleate neurons were estimated. Furthermore, the mean perikaryal (somal) volume of mononucleate and binucleate neurons was estimated using the vertical nucleator. The main findings of this study were a 154% increase in the SCG volume, a 95% increase in the total number of mononucleate SCG neurons and a 50% increase in the total volume of SCG neurons. In conclusion, apart from neuron number, different adaptive mechanisms may coexist in the autonomic nervous system to guarantee a functional homeostasis during ageing, which is not always associated with neuron losses. Anat Rec, 292:966-975, 2009. (C) 2009 Wiley-Liss, Inc. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-07-01 2014-05-20T13:15:47Z 2014-05-20T13:15:47Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1002/ar.20918 Anatomical Record-advances In Integrative Anatomy and Evolutionary Biology. Hoboken: Wiley-liss, v. 292, n. 7, p. 966-975, 2009. 1932-8486 http://hdl.handle.net/11449/2819 10.1002/ar.20918 WOS:000267716200007 |
url |
http://dx.doi.org/10.1002/ar.20918 http://hdl.handle.net/11449/2819 |
identifier_str_mv |
Anatomical Record-advances In Integrative Anatomy and Evolutionary Biology. Hoboken: Wiley-liss, v. 292, n. 7, p. 966-975, 2009. 1932-8486 10.1002/ar.20918 WOS:000267716200007 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Anatomical Record-advances In Integrative Anatomy and Evolutionary Biology 1.373 0,766 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
966-975 |
dc.publisher.none.fl_str_mv |
Wiley-liss |
publisher.none.fl_str_mv |
Wiley-liss |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1797790368248365056 |