Chronic capsiate supplementation increases fat-free mass and upper body strength but not the inflammatory response to resistance exercise in young untrained men: a randomized, placebo-controlled and double-blind study
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1186/s12970-021-00446-0 http://hdl.handle.net/11449/221885 |
Resumo: | Background: Acute capsaicinoid and capsinoid supplementation has endurance and resistance exercise benefits; however, if these short-term performance benefits translate into chronic benefits when combined with resistance training is currently unknown. This study investigated changes of chronic Capsiate supplementation on muscular adaptations, inflammatory response and performance in untrained men. Methods: Twenty untrained men were randomized to ingest 12 mg Capsiate (CAP) or placebo in a parallel, double-blind design. Body composition and performance were measured at pre-training and after 6 weeks of resistance training. An acute resistance exercise session test was performed pre and post-intervention. Blood samples were collected at rest and post-resistance exercise to analyze Tumor necrosis factor- (TNF-), Soluble TNF- receptor (sTNF-r), Interleukin-6 (IL-6) and Interleukin-10 (IL-10). Results: Exercise and CAP supplementation increased fat-free mass in comparison to baseline by 1.5 kg (P < 0.001), however, the majority of the increase (1.0 kg) resulted from an increase in total body water. The CAP change scores for fat-free mass were significantly greater in comparison to the placebo (CAP ∆%= 2.1 ± 1.8 %, PLA ∆%= 0.7 ± 1.3 %, P = 0.043) and there was a significant difference between groups in the bench press exercise (P = 0.034) with greater upper body strength change score for CAP (∆%= 13.4 ± 9.1 %) compared to placebo (∆%= 5.8 ± 5.2 %), P = 0.041. CAP had no effect on lower body strength and no supplementation interactions were observed for all cytokines in response to acute resistance exercise (P > 0.05). Conclusion: Chronic Capsiate supplementation combined with resistance training during short period (6 weeks) increased fat-free mass and upper body strength but not inflammatory response and performance in young untrained men. |
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Chronic capsiate supplementation increases fat-free mass and upper body strength but not the inflammatory response to resistance exercise in young untrained men: a randomized, placebo-controlled and double-blind studyHypertrophyPerformancePre-workoutStrength trainingBackground: Acute capsaicinoid and capsinoid supplementation has endurance and resistance exercise benefits; however, if these short-term performance benefits translate into chronic benefits when combined with resistance training is currently unknown. This study investigated changes of chronic Capsiate supplementation on muscular adaptations, inflammatory response and performance in untrained men. Methods: Twenty untrained men were randomized to ingest 12 mg Capsiate (CAP) or placebo in a parallel, double-blind design. Body composition and performance were measured at pre-training and after 6 weeks of resistance training. An acute resistance exercise session test was performed pre and post-intervention. Blood samples were collected at rest and post-resistance exercise to analyze Tumor necrosis factor- (TNF-), Soluble TNF- receptor (sTNF-r), Interleukin-6 (IL-6) and Interleukin-10 (IL-10). Results: Exercise and CAP supplementation increased fat-free mass in comparison to baseline by 1.5 kg (P < 0.001), however, the majority of the increase (1.0 kg) resulted from an increase in total body water. The CAP change scores for fat-free mass were significantly greater in comparison to the placebo (CAP ∆%= 2.1 ± 1.8 %, PLA ∆%= 0.7 ± 1.3 %, P = 0.043) and there was a significant difference between groups in the bench press exercise (P = 0.034) with greater upper body strength change score for CAP (∆%= 13.4 ± 9.1 %) compared to placebo (∆%= 5.8 ± 5.2 %), P = 0.041. CAP had no effect on lower body strength and no supplementation interactions were observed for all cytokines in response to acute resistance exercise (P > 0.05). Conclusion: Chronic Capsiate supplementation combined with resistance training during short period (6 weeks) increased fat-free mass and upper body strength but not inflammatory response and performance in young untrained men.Immunometabolism of Skeletal Muscle and Exercise Research Group Department of Physical Education Federal University of Piauí (UFPI), “Ministro Petrônio Portella” CampusDepartment of Exercise Physiology University of LynchburgIncrenovo LLC, 2138 E Lafayette PlLaboratory of Cellular and Molecular Biology of Skeletal Muscle (LABCEMME) Department of Physical Education Federal University of MaranhãoDepartment of Nutrition University of Western São Paulo (UNOESTE)Department of Biophysics and Physiology Federal University of Piaui, Campus Minister Petrônio PortelaExercise and Immunometabolism Research Group Department of Physical Education São Paulo State University (UNESP)University São Judas TadeuAssociate Professor at Graduation Program in Science and Health Federal University of Piaui (UFPI)Exercise and Immunometabolism Research Group Department of Physical Education São Paulo State University (UNESP)Federal University of Piauí (UFPI)University of LynchburgIncrenovo LLCFederal University of MaranhãoUniversity of Western São Paulo (UNOESTE)Federal University of PiauiUniversidade Estadual Paulista (UNESP)University São Judas TadeuFederal University of Piaui (UFPI)de Moura e Silva, Vilton Emanoel LopesCholewa, Jason MichaelJäger, RalfZanchi, Nelo Eidyde Freitas, Marcelo Conradode Moura, Rayane CarvalhoBarros, Esmeralda Maria LustosaAntunes, Barbara Moura [UNESP]Caperuto, Erico ChagasRibeiro, Sergio Luiz GalanLira, Fabio Santos [UNESP]Pereira dos Santos, Marcos AntônioRossi, Fabrício Eduardo2022-04-28T19:41:04Z2022-04-28T19:41:04Z2021-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1186/s12970-021-00446-0Journal of the International Society of Sports Nutrition, v. 18, n. 1, 2021.1550-2783http://hdl.handle.net/11449/22188510.1186/s12970-021-00446-02-s2.0-85109018571Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of the International Society of Sports Nutritioninfo:eu-repo/semantics/openAccess2022-04-28T19:41:04Zoai:repositorio.unesp.br:11449/221885Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-04-28T19:41:04Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Chronic capsiate supplementation increases fat-free mass and upper body strength but not the inflammatory response to resistance exercise in young untrained men: a randomized, placebo-controlled and double-blind study |
title |
Chronic capsiate supplementation increases fat-free mass and upper body strength but not the inflammatory response to resistance exercise in young untrained men: a randomized, placebo-controlled and double-blind study |
spellingShingle |
Chronic capsiate supplementation increases fat-free mass and upper body strength but not the inflammatory response to resistance exercise in young untrained men: a randomized, placebo-controlled and double-blind study de Moura e Silva, Vilton Emanoel Lopes Hypertrophy Performance Pre-workout Strength training |
title_short |
Chronic capsiate supplementation increases fat-free mass and upper body strength but not the inflammatory response to resistance exercise in young untrained men: a randomized, placebo-controlled and double-blind study |
title_full |
Chronic capsiate supplementation increases fat-free mass and upper body strength but not the inflammatory response to resistance exercise in young untrained men: a randomized, placebo-controlled and double-blind study |
title_fullStr |
Chronic capsiate supplementation increases fat-free mass and upper body strength but not the inflammatory response to resistance exercise in young untrained men: a randomized, placebo-controlled and double-blind study |
title_full_unstemmed |
Chronic capsiate supplementation increases fat-free mass and upper body strength but not the inflammatory response to resistance exercise in young untrained men: a randomized, placebo-controlled and double-blind study |
title_sort |
Chronic capsiate supplementation increases fat-free mass and upper body strength but not the inflammatory response to resistance exercise in young untrained men: a randomized, placebo-controlled and double-blind study |
author |
de Moura e Silva, Vilton Emanoel Lopes |
author_facet |
de Moura e Silva, Vilton Emanoel Lopes Cholewa, Jason Michael Jäger, Ralf Zanchi, Nelo Eidy de Freitas, Marcelo Conrado de Moura, Rayane Carvalho Barros, Esmeralda Maria Lustosa Antunes, Barbara Moura [UNESP] Caperuto, Erico Chagas Ribeiro, Sergio Luiz Galan Lira, Fabio Santos [UNESP] Pereira dos Santos, Marcos Antônio Rossi, Fabrício Eduardo |
author_role |
author |
author2 |
Cholewa, Jason Michael Jäger, Ralf Zanchi, Nelo Eidy de Freitas, Marcelo Conrado de Moura, Rayane Carvalho Barros, Esmeralda Maria Lustosa Antunes, Barbara Moura [UNESP] Caperuto, Erico Chagas Ribeiro, Sergio Luiz Galan Lira, Fabio Santos [UNESP] Pereira dos Santos, Marcos Antônio Rossi, Fabrício Eduardo |
author2_role |
author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Federal University of Piauí (UFPI) University of Lynchburg Increnovo LLC Federal University of Maranhão University of Western São Paulo (UNOESTE) Federal University of Piaui Universidade Estadual Paulista (UNESP) University São Judas Tadeu Federal University of Piaui (UFPI) |
dc.contributor.author.fl_str_mv |
de Moura e Silva, Vilton Emanoel Lopes Cholewa, Jason Michael Jäger, Ralf Zanchi, Nelo Eidy de Freitas, Marcelo Conrado de Moura, Rayane Carvalho Barros, Esmeralda Maria Lustosa Antunes, Barbara Moura [UNESP] Caperuto, Erico Chagas Ribeiro, Sergio Luiz Galan Lira, Fabio Santos [UNESP] Pereira dos Santos, Marcos Antônio Rossi, Fabrício Eduardo |
dc.subject.por.fl_str_mv |
Hypertrophy Performance Pre-workout Strength training |
topic |
Hypertrophy Performance Pre-workout Strength training |
description |
Background: Acute capsaicinoid and capsinoid supplementation has endurance and resistance exercise benefits; however, if these short-term performance benefits translate into chronic benefits when combined with resistance training is currently unknown. This study investigated changes of chronic Capsiate supplementation on muscular adaptations, inflammatory response and performance in untrained men. Methods: Twenty untrained men were randomized to ingest 12 mg Capsiate (CAP) or placebo in a parallel, double-blind design. Body composition and performance were measured at pre-training and after 6 weeks of resistance training. An acute resistance exercise session test was performed pre and post-intervention. Blood samples were collected at rest and post-resistance exercise to analyze Tumor necrosis factor- (TNF-), Soluble TNF- receptor (sTNF-r), Interleukin-6 (IL-6) and Interleukin-10 (IL-10). Results: Exercise and CAP supplementation increased fat-free mass in comparison to baseline by 1.5 kg (P < 0.001), however, the majority of the increase (1.0 kg) resulted from an increase in total body water. The CAP change scores for fat-free mass were significantly greater in comparison to the placebo (CAP ∆%= 2.1 ± 1.8 %, PLA ∆%= 0.7 ± 1.3 %, P = 0.043) and there was a significant difference between groups in the bench press exercise (P = 0.034) with greater upper body strength change score for CAP (∆%= 13.4 ± 9.1 %) compared to placebo (∆%= 5.8 ± 5.2 %), P = 0.041. CAP had no effect on lower body strength and no supplementation interactions were observed for all cytokines in response to acute resistance exercise (P > 0.05). Conclusion: Chronic Capsiate supplementation combined with resistance training during short period (6 weeks) increased fat-free mass and upper body strength but not inflammatory response and performance in young untrained men. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-12-01 2022-04-28T19:41:04Z 2022-04-28T19:41:04Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1186/s12970-021-00446-0 Journal of the International Society of Sports Nutrition, v. 18, n. 1, 2021. 1550-2783 http://hdl.handle.net/11449/221885 10.1186/s12970-021-00446-0 2-s2.0-85109018571 |
url |
http://dx.doi.org/10.1186/s12970-021-00446-0 http://hdl.handle.net/11449/221885 |
identifier_str_mv |
Journal of the International Society of Sports Nutrition, v. 18, n. 1, 2021. 1550-2783 10.1186/s12970-021-00446-0 2-s2.0-85109018571 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of the International Society of Sports Nutrition |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1797789812995915776 |