Humoral immune response in dogs and cats vaccinated against rabies in southeastern Brazil
Autor(a) principal: | |
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Data de Publicação: | 2013 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1186/1678-9199-19-17 http://hdl.handle.net/11449/113379 |
Resumo: | Background: Brazil holds annual nationwide public campaigns to vaccinate dogs and cats against rabies. The presence of rabies antibodies in these animals, which are among the main transmitters of rabies to humans, is a good indicator that they are immunized and protected.Methods: In the present study we analyzed 834 serum samples from dogs and cats from the Southeast of Brazil (Presidente Prudente and Dracena cities), 12 months after the 2009 vaccination campaign. We used the technique known as rapid fluorescent focus inhibition test (RFFIT) and considered reactant those sera with values higher 0.5 IU/mL.Results and discussion: Reactant sample results in Presidente Prudente were 153 (51.0%) for dogs and 59 (32.6%) for cats, and in Dracena 110 (52.1%) for dogs and 71 (50.0%) for cats. We discussed vaccine coverage of animals involved in this experiment, and observed low titers < 0.5 IU/mL, especially in cats from Presidente Prudente.Conclusion: According to the results presented in our experiment, we suggest that titers below 0.5 IU/mL are worrisome and that, for multiple reasons, animals should be immunized against rabies in the period between public vaccination campaigns. Hence, the desired vaccine coverage was not accomplished, especially among cats from Presidente Prudente. |
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Humoral immune response in dogs and cats vaccinated against rabies in southeastern BrazilRabiesVaccinationDogsCatsHumoral immune responseBackground: Brazil holds annual nationwide public campaigns to vaccinate dogs and cats against rabies. The presence of rabies antibodies in these animals, which are among the main transmitters of rabies to humans, is a good indicator that they are immunized and protected.Methods: In the present study we analyzed 834 serum samples from dogs and cats from the Southeast of Brazil (Presidente Prudente and Dracena cities), 12 months after the 2009 vaccination campaign. We used the technique known as rapid fluorescent focus inhibition test (RFFIT) and considered reactant those sera with values higher 0.5 IU/mL.Results and discussion: Reactant sample results in Presidente Prudente were 153 (51.0%) for dogs and 59 (32.6%) for cats, and in Dracena 110 (52.1%) for dogs and 71 (50.0%) for cats. We discussed vaccine coverage of animals involved in this experiment, and observed low titers < 0.5 IU/mL, especially in cats from Presidente Prudente.Conclusion: According to the results presented in our experiment, we suggest that titers below 0.5 IU/mL are worrisome and that, for multiple reasons, animals should be immunized against rabies in the period between public vaccination campaigns. Hence, the desired vaccine coverage was not accomplished, especially among cats from Presidente Prudente.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Sao Paulo Agcy Agribusiness Technol APTA, Presidente Prudente, SP, BrazilZoonosis Control Ctr, Presidente Prudente, SP, BrazilZoonosis Control Ctr, Dracena, SP, BrazilUNESP Univ Estadual Paulista, Sao Paulo State Univ, Sch Sci & Technol, Dept Stat, Presidente Prudente, SP, BrazilUNESP Univ Estadual Paulista, Sao Paulo State Univ, Sch Sci & Technol, Dept Stat, Presidente Prudente, SP, BrazilFAPESP: 08/54266-3Biomed Central Ltd.Agência Paulista de Tecnologia dos Agronegócios (APTA)Zoonosis Control CtrUniversidade Estadual Paulista (Unesp)Albas, AvelinoPicolo, Mileia RicciSoares, Celio NereuUlbano Bachega, Hugo VagnerTarumoto, Mario Hissamitsu [UNESP]2014-12-03T13:11:39Z2014-12-03T13:11:39Z2013-07-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article3application/pdfhttp://dx.doi.org/10.1186/1678-9199-19-17Journal Of Venomous Animals And Toxins Including Tropical Diseases. London: Biomed Central Ltd, v. 19, 3 p., 2013.1678-9199http://hdl.handle.net/11449/11337910.1186/1678-9199-19-17WOS:000322840400001WOS000322840400001.pdf1134493123277993Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Venomous Animals and Toxins Including Tropical Diseases1.7820,573info:eu-repo/semantics/openAccess2023-12-20T06:18:53Zoai:repositorio.unesp.br:11449/113379Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-12-20T06:18:53Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Humoral immune response in dogs and cats vaccinated against rabies in southeastern Brazil |
title |
Humoral immune response in dogs and cats vaccinated against rabies in southeastern Brazil |
spellingShingle |
Humoral immune response in dogs and cats vaccinated against rabies in southeastern Brazil Albas, Avelino Rabies Vaccination Dogs Cats Humoral immune response |
title_short |
Humoral immune response in dogs and cats vaccinated against rabies in southeastern Brazil |
title_full |
Humoral immune response in dogs and cats vaccinated against rabies in southeastern Brazil |
title_fullStr |
Humoral immune response in dogs and cats vaccinated against rabies in southeastern Brazil |
title_full_unstemmed |
Humoral immune response in dogs and cats vaccinated against rabies in southeastern Brazil |
title_sort |
Humoral immune response in dogs and cats vaccinated against rabies in southeastern Brazil |
author |
Albas, Avelino |
author_facet |
Albas, Avelino Picolo, Mileia Ricci Soares, Celio Nereu Ulbano Bachega, Hugo Vagner Tarumoto, Mario Hissamitsu [UNESP] |
author_role |
author |
author2 |
Picolo, Mileia Ricci Soares, Celio Nereu Ulbano Bachega, Hugo Vagner Tarumoto, Mario Hissamitsu [UNESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Agência Paulista de Tecnologia dos Agronegócios (APTA) Zoonosis Control Ctr Universidade Estadual Paulista (Unesp) |
dc.contributor.author.fl_str_mv |
Albas, Avelino Picolo, Mileia Ricci Soares, Celio Nereu Ulbano Bachega, Hugo Vagner Tarumoto, Mario Hissamitsu [UNESP] |
dc.subject.por.fl_str_mv |
Rabies Vaccination Dogs Cats Humoral immune response |
topic |
Rabies Vaccination Dogs Cats Humoral immune response |
description |
Background: Brazil holds annual nationwide public campaigns to vaccinate dogs and cats against rabies. The presence of rabies antibodies in these animals, which are among the main transmitters of rabies to humans, is a good indicator that they are immunized and protected.Methods: In the present study we analyzed 834 serum samples from dogs and cats from the Southeast of Brazil (Presidente Prudente and Dracena cities), 12 months after the 2009 vaccination campaign. We used the technique known as rapid fluorescent focus inhibition test (RFFIT) and considered reactant those sera with values higher 0.5 IU/mL.Results and discussion: Reactant sample results in Presidente Prudente were 153 (51.0%) for dogs and 59 (32.6%) for cats, and in Dracena 110 (52.1%) for dogs and 71 (50.0%) for cats. We discussed vaccine coverage of animals involved in this experiment, and observed low titers < 0.5 IU/mL, especially in cats from Presidente Prudente.Conclusion: According to the results presented in our experiment, we suggest that titers below 0.5 IU/mL are worrisome and that, for multiple reasons, animals should be immunized against rabies in the period between public vaccination campaigns. Hence, the desired vaccine coverage was not accomplished, especially among cats from Presidente Prudente. |
publishDate |
2013 |
dc.date.none.fl_str_mv |
2013-07-30 2014-12-03T13:11:39Z 2014-12-03T13:11:39Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1186/1678-9199-19-17 Journal Of Venomous Animals And Toxins Including Tropical Diseases. London: Biomed Central Ltd, v. 19, 3 p., 2013. 1678-9199 http://hdl.handle.net/11449/113379 10.1186/1678-9199-19-17 WOS:000322840400001 WOS000322840400001.pdf 1134493123277993 |
url |
http://dx.doi.org/10.1186/1678-9199-19-17 http://hdl.handle.net/11449/113379 |
identifier_str_mv |
Journal Of Venomous Animals And Toxins Including Tropical Diseases. London: Biomed Central Ltd, v. 19, 3 p., 2013. 1678-9199 10.1186/1678-9199-19-17 WOS:000322840400001 WOS000322840400001.pdf 1134493123277993 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Venomous Animals and Toxins Including Tropical Diseases 1.782 0,573 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
3 application/pdf |
dc.publisher.none.fl_str_mv |
Biomed Central Ltd. |
publisher.none.fl_str_mv |
Biomed Central Ltd. |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1792962126340423680 |