Competitive Host-guest Electrochemical Detection of Ivermectin Drug Using a β-cyclodextrin/Graphene-based Electrode

Detalhes bibliográficos
Autor(a) principal: Silva, Martin K. L. [UNESP]
Data de Publicação: 2022
Outros Autores: Simões, Rafael P. [UNESP], Leão, Alcides L. [UNESP], Lapa, Rainer M. L., Rascón, Jesús, Cesarino, Ivana [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1002/elan.202100649
http://hdl.handle.net/11449/240158
Resumo: The present study describes the novel development and application of an ivermectin (IVM) sensing electrochemical platform based on reduced graphene oxide (rGO) and the macrocyclic host β-cyclodextrin (β-CD) molecule. The sensing method was based in the host-guest characteristics of β-CD and competitive interaction between the target analyte and the methylene blue (MB) redox probe. Differential pulse voltammetry (DPV) was employed for the detection of IVM and a linear response between 0.5 and 40.0 μmol L−1 with a limit of detection of 0.25 μmol L−1 was obtained using the glassy carbon (GC)/rGO/β-CD electrode. The sensing platform was successfully applied for the detection of IVM in tap water samples, which may expand the applications of β-CD towards the analysis of other chemical species.
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spelling Competitive Host-guest Electrochemical Detection of Ivermectin Drug Using a β-cyclodextrin/Graphene-based ElectrodeElectrochemical sensorsGrapheneHost-guest interactionIvermectinβ-CyclodextrinThe present study describes the novel development and application of an ivermectin (IVM) sensing electrochemical platform based on reduced graphene oxide (rGO) and the macrocyclic host β-cyclodextrin (β-CD) molecule. The sensing method was based in the host-guest characteristics of β-CD and competitive interaction between the target analyte and the methylene blue (MB) redox probe. Differential pulse voltammetry (DPV) was employed for the detection of IVM and a linear response between 0.5 and 40.0 μmol L−1 with a limit of detection of 0.25 μmol L−1 was obtained using the glassy carbon (GC)/rGO/β-CD electrode. The sensing platform was successfully applied for the detection of IVM in tap water samples, which may expand the applications of β-CD towards the analysis of other chemical species.São Paulo State University (UNESP) School of Agriculture, Avenida Universitária, n° 3780Universidad Nacional Toribio Rodríguez de Mendoza de Amazonas (UNTRM) Instituto de Investigación en Ganadería y Biotecnología (IGBI), AmazonasUniversidad Nacional Toribio Rodríguez de Mendoza de Amazonas (UNTRM) Facultad de Ciencias de la Salud (FACISA), AmazonasUniversidad Nacional Toribio Rodríguez de Mendoza de Amazonas (UNTRM) Instituto de Investigación para el Desarrollo Sustentable de Ceja de Selva (INDES-CES), AmazonasSão Paulo State University (UNESP) School of Agriculture, Avenida Universitária, n° 3780Universidade Estadual Paulista (UNESP)Instituto de Investigación en Ganadería y Biotecnología (IGBI)Facultad de Ciencias de la Salud (FACISA)Instituto de Investigación para el Desarrollo Sustentable de Ceja de Selva (INDES-CES)Silva, Martin K. L. [UNESP]Simões, Rafael P. [UNESP]Leão, Alcides L. [UNESP]Lapa, Rainer M. L.Rascón, JesúsCesarino, Ivana [UNESP]2023-03-01T20:04:05Z2023-03-01T20:04:05Z2022-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1002/elan.202100649Electroanalysis.1521-41091040-0397http://hdl.handle.net/11449/24015810.1002/elan.2021006492-s2.0-85131013655Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengElectroanalysisinfo:eu-repo/semantics/openAccess2023-03-01T20:04:05Zoai:repositorio.unesp.br:11449/240158Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-03-01T20:04:05Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Competitive Host-guest Electrochemical Detection of Ivermectin Drug Using a β-cyclodextrin/Graphene-based Electrode
title Competitive Host-guest Electrochemical Detection of Ivermectin Drug Using a β-cyclodextrin/Graphene-based Electrode
spellingShingle Competitive Host-guest Electrochemical Detection of Ivermectin Drug Using a β-cyclodextrin/Graphene-based Electrode
Silva, Martin K. L. [UNESP]
Electrochemical sensors
Graphene
Host-guest interaction
Ivermectin
β-Cyclodextrin
title_short Competitive Host-guest Electrochemical Detection of Ivermectin Drug Using a β-cyclodextrin/Graphene-based Electrode
title_full Competitive Host-guest Electrochemical Detection of Ivermectin Drug Using a β-cyclodextrin/Graphene-based Electrode
title_fullStr Competitive Host-guest Electrochemical Detection of Ivermectin Drug Using a β-cyclodextrin/Graphene-based Electrode
title_full_unstemmed Competitive Host-guest Electrochemical Detection of Ivermectin Drug Using a β-cyclodextrin/Graphene-based Electrode
title_sort Competitive Host-guest Electrochemical Detection of Ivermectin Drug Using a β-cyclodextrin/Graphene-based Electrode
author Silva, Martin K. L. [UNESP]
author_facet Silva, Martin K. L. [UNESP]
Simões, Rafael P. [UNESP]
Leão, Alcides L. [UNESP]
Lapa, Rainer M. L.
Rascón, Jesús
Cesarino, Ivana [UNESP]
author_role author
author2 Simões, Rafael P. [UNESP]
Leão, Alcides L. [UNESP]
Lapa, Rainer M. L.
Rascón, Jesús
Cesarino, Ivana [UNESP]
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
Instituto de Investigación en Ganadería y Biotecnología (IGBI)
Facultad de Ciencias de la Salud (FACISA)
Instituto de Investigación para el Desarrollo Sustentable de Ceja de Selva (INDES-CES)
dc.contributor.author.fl_str_mv Silva, Martin K. L. [UNESP]
Simões, Rafael P. [UNESP]
Leão, Alcides L. [UNESP]
Lapa, Rainer M. L.
Rascón, Jesús
Cesarino, Ivana [UNESP]
dc.subject.por.fl_str_mv Electrochemical sensors
Graphene
Host-guest interaction
Ivermectin
β-Cyclodextrin
topic Electrochemical sensors
Graphene
Host-guest interaction
Ivermectin
β-Cyclodextrin
description The present study describes the novel development and application of an ivermectin (IVM) sensing electrochemical platform based on reduced graphene oxide (rGO) and the macrocyclic host β-cyclodextrin (β-CD) molecule. The sensing method was based in the host-guest characteristics of β-CD and competitive interaction between the target analyte and the methylene blue (MB) redox probe. Differential pulse voltammetry (DPV) was employed for the detection of IVM and a linear response between 0.5 and 40.0 μmol L−1 with a limit of detection of 0.25 μmol L−1 was obtained using the glassy carbon (GC)/rGO/β-CD electrode. The sensing platform was successfully applied for the detection of IVM in tap water samples, which may expand the applications of β-CD towards the analysis of other chemical species.
publishDate 2022
dc.date.none.fl_str_mv 2022-01-01
2023-03-01T20:04:05Z
2023-03-01T20:04:05Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1002/elan.202100649
Electroanalysis.
1521-4109
1040-0397
http://hdl.handle.net/11449/240158
10.1002/elan.202100649
2-s2.0-85131013655
url http://dx.doi.org/10.1002/elan.202100649
http://hdl.handle.net/11449/240158
identifier_str_mv Electroanalysis.
1521-4109
1040-0397
10.1002/elan.202100649
2-s2.0-85131013655
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Electroanalysis
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1797790417786241024

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