Age-related macular degeneration: an overview

Detalhes bibliográficos
Autor(a) principal: de Almeida Torres, Rogil José [UNESP]
Data de Publicação: 2021
Outros Autores: dos Anjos Ferreira, Ana Lúcia [UNESP]
Tipo de documento: Artigo
Idioma: eng
por
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.37039/1982.8551.20210038
http://hdl.handle.net/11449/222728
Resumo: Age-related macular degeneration is the most important cause of irreversible vision loss in the elderly and has been considered a severe public health problem. Current treatments have only been successful in delaying the loss of central vision. Due to increased life expectancy, governments and researchers have been challenged to seek more efficient and successful treatments for age-related macular degeneration. Considering its relevance for public health and the need of further research, this article aims to address age-related macular degeneration objectively, tackling on the current knowledge about its pathophysiology, potential molecular biomarkers, main prevention procedures and treatments, as well as introducing possible molecules that may be a therapeutic target in this disease.
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spelling Age-related macular degeneration: an overviewDegeneração macular relacionada ã idade: um panorama geralBiomarkersInflammationMacular degenerationOxidative stressPrimary preventionRetinal pigment epitheliumSecondary preventionAge-related macular degeneration is the most important cause of irreversible vision loss in the elderly and has been considered a severe public health problem. Current treatments have only been successful in delaying the loss of central vision. Due to increased life expectancy, governments and researchers have been challenged to seek more efficient and successful treatments for age-related macular degeneration. Considering its relevance for public health and the need of further research, this article aims to address age-related macular degeneration objectively, tackling on the current knowledge about its pathophysiology, potential molecular biomarkers, main prevention procedures and treatments, as well as introducing possible molecules that may be a therapeutic target in this disease.Universidade Estadual Paulista “Júlio de Mesquita Filho”Universidade Estadual Paulista “Júlio de Mesquita Filho”Universidade Estadual Paulista (UNESP)de Almeida Torres, Rogil José [UNESP]dos Anjos Ferreira, Ana Lúcia [UNESP]2022-04-28T19:46:26Z2022-04-28T19:46:26Z2021-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article1-4http://dx.doi.org/10.37039/1982.8551.20210038Revista Brasileira de Oftalmologia, v. 80, n. 5, p. 1-4, 2021.1982-85510034-7280http://hdl.handle.net/11449/22272810.37039/1982.8551.202100382-s2.0-85117881858Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengporRevista Brasileira de Oftalmologiainfo:eu-repo/semantics/openAccess2022-04-28T19:46:26Zoai:repositorio.unesp.br:11449/222728Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-04-28T19:46:26Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Age-related macular degeneration: an overview
Degeneração macular relacionada ã idade: um panorama geral
title Age-related macular degeneration: an overview
spellingShingle Age-related macular degeneration: an overview
de Almeida Torres, Rogil José [UNESP]
Biomarkers
Inflammation
Macular degeneration
Oxidative stress
Primary prevention
Retinal pigment epithelium
Secondary prevention
title_short Age-related macular degeneration: an overview
title_full Age-related macular degeneration: an overview
title_fullStr Age-related macular degeneration: an overview
title_full_unstemmed Age-related macular degeneration: an overview
title_sort Age-related macular degeneration: an overview
author de Almeida Torres, Rogil José [UNESP]
author_facet de Almeida Torres, Rogil José [UNESP]
dos Anjos Ferreira, Ana Lúcia [UNESP]
author_role author
author2 dos Anjos Ferreira, Ana Lúcia [UNESP]
author2_role author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (UNESP)
dc.contributor.author.fl_str_mv de Almeida Torres, Rogil José [UNESP]
dos Anjos Ferreira, Ana Lúcia [UNESP]
dc.subject.por.fl_str_mv Biomarkers
Inflammation
Macular degeneration
Oxidative stress
Primary prevention
Retinal pigment epithelium
Secondary prevention
topic Biomarkers
Inflammation
Macular degeneration
Oxidative stress
Primary prevention
Retinal pigment epithelium
Secondary prevention
description Age-related macular degeneration is the most important cause of irreversible vision loss in the elderly and has been considered a severe public health problem. Current treatments have only been successful in delaying the loss of central vision. Due to increased life expectancy, governments and researchers have been challenged to seek more efficient and successful treatments for age-related macular degeneration. Considering its relevance for public health and the need of further research, this article aims to address age-related macular degeneration objectively, tackling on the current knowledge about its pathophysiology, potential molecular biomarkers, main prevention procedures and treatments, as well as introducing possible molecules that may be a therapeutic target in this disease.
publishDate 2021
dc.date.none.fl_str_mv 2021-01-01
2022-04-28T19:46:26Z
2022-04-28T19:46:26Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.37039/1982.8551.20210038
Revista Brasileira de Oftalmologia, v. 80, n. 5, p. 1-4, 2021.
1982-8551
0034-7280
http://hdl.handle.net/11449/222728
10.37039/1982.8551.20210038
2-s2.0-85117881858
url http://dx.doi.org/10.37039/1982.8551.20210038
http://hdl.handle.net/11449/222728
identifier_str_mv Revista Brasileira de Oftalmologia, v. 80, n. 5, p. 1-4, 2021.
1982-8551
0034-7280
10.37039/1982.8551.20210038
2-s2.0-85117881858
dc.language.iso.fl_str_mv eng
por
language eng
por
dc.relation.none.fl_str_mv Revista Brasileira de Oftalmologia
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 1-4
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1799964567282909184

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