Bioprospecting macroalgae, marine and terrestrial invertebrates & their associated microbiota
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/1676-0611-BN-2022-1345 http://hdl.handle.net/11449/242167 |
Resumo: | The present review aims the discussion of the impact of the bioprospection initiative developed by the projects associated to BIOprospecTA, a subprogram of the program BIOTA, supported by FAPESP. This review brings a summary of the main results produced by the projects investigating natural products (NPs) from non-plants organisms, as examples of the success of this initiative, focusing on the progresses achieved by the projects related to NPs from macroalgae, marine invertebrates, arthropods and associated microorganisms. Macroalgae are one of the most studied groups in Brazil with the isolation of many bioactive compounds including lipids, carotenoids, phycocolloids, lectins, mycosporine-like amino acids and halogenated compounds. Marine invertebrates and associated microorganisms have been more systematically studied in the last thirty years, revealing unique compounds, with potent biological activities. The venoms of Hymenopteran insects were also extensively studied, resulting in the identification of hundreds of peptides, which were used to create a chemical library that contributed for the identification of leader models for the development of antifungal, antiparasitic, and anticancer compounds. The built knowledge of Hymenopteran venoms permitted the development of an equine hyperimmune serum anti honeybee venom. Amongst the microorganisms associated with insects the bioprospecting strategy was to understand the molecular basis of intra-and interspecies interactions (Chemical Ecology), translating this knowledge to possible biotechnological applications. The results discussed here reinforce the importance of BIOprospecTA program on the development of research with highly innovative potential in Brazil. |
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Bioprospecting macroalgae, marine and terrestrial invertebrates & their associated microbiotaBioprospecção de macroalgas, invertebrados marinhos e terrestres e microbiota associadaarthropodsbioeconomybiological active compoundsinsectsmicrobiotaNatural productsThe present review aims the discussion of the impact of the bioprospection initiative developed by the projects associated to BIOprospecTA, a subprogram of the program BIOTA, supported by FAPESP. This review brings a summary of the main results produced by the projects investigating natural products (NPs) from non-plants organisms, as examples of the success of this initiative, focusing on the progresses achieved by the projects related to NPs from macroalgae, marine invertebrates, arthropods and associated microorganisms. Macroalgae are one of the most studied groups in Brazil with the isolation of many bioactive compounds including lipids, carotenoids, phycocolloids, lectins, mycosporine-like amino acids and halogenated compounds. Marine invertebrates and associated microorganisms have been more systematically studied in the last thirty years, revealing unique compounds, with potent biological activities. The venoms of Hymenopteran insects were also extensively studied, resulting in the identification of hundreds of peptides, which were used to create a chemical library that contributed for the identification of leader models for the development of antifungal, antiparasitic, and anticancer compounds. The built knowledge of Hymenopteran venoms permitted the development of an equine hyperimmune serum anti honeybee venom. Amongst the microorganisms associated with insects the bioprospecting strategy was to understand the molecular basis of intra-and interspecies interactions (Chemical Ecology), translating this knowledge to possible biotechnological applications. The results discussed here reinforce the importance of BIOprospecTA program on the development of research with highly innovative potential in Brazil.Universidade de São Paulo Instituto de Ciências Biomédicas, SPUniversidade de São Paulo Instituto de Química, SPUniversidade de São Paulo Faculdade de Ciências Farmacêuticas de Ribeirão Preto, SPUniversidade Estadual Paulista “Júlio de Mesquita Filho” Instituto de Biociências, SPUniversidade Estadual Paulista “Júlio de Mesquita Filho” Instituto de Biociências, SPUniversidade de São Paulo (USP)Universidade Estadual Paulista (UNESP)Costa-Lotufo, Leticia VerasColepicolo, PioPupo, Mônica TallaricoPalma, Mario Sergio [UNESP]2023-03-02T10:44:16Z2023-03-02T10:44:16Z2022-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1590/1676-0611-BN-2022-1345Biota Neotropica, v. 22, n. Spe, 2022.1676-06111676-0603http://hdl.handle.net/11449/24216710.1590/1676-0611-BN-2022-13452-s2.0-85136237782Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBiota Neotropicainfo:eu-repo/semantics/openAccess2023-03-02T10:44:16Zoai:repositorio.unesp.br:11449/242167Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-03-02T10:44:16Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Bioprospecting macroalgae, marine and terrestrial invertebrates & their associated microbiota Bioprospecção de macroalgas, invertebrados marinhos e terrestres e microbiota associada |
title |
Bioprospecting macroalgae, marine and terrestrial invertebrates & their associated microbiota |
spellingShingle |
Bioprospecting macroalgae, marine and terrestrial invertebrates & their associated microbiota Costa-Lotufo, Leticia Veras arthropods bioeconomy biological active compounds insects microbiota Natural products |
title_short |
Bioprospecting macroalgae, marine and terrestrial invertebrates & their associated microbiota |
title_full |
Bioprospecting macroalgae, marine and terrestrial invertebrates & their associated microbiota |
title_fullStr |
Bioprospecting macroalgae, marine and terrestrial invertebrates & their associated microbiota |
title_full_unstemmed |
Bioprospecting macroalgae, marine and terrestrial invertebrates & their associated microbiota |
title_sort |
Bioprospecting macroalgae, marine and terrestrial invertebrates & their associated microbiota |
author |
Costa-Lotufo, Leticia Veras |
author_facet |
Costa-Lotufo, Leticia Veras Colepicolo, Pio Pupo, Mônica Tallarico Palma, Mario Sergio [UNESP] |
author_role |
author |
author2 |
Colepicolo, Pio Pupo, Mônica Tallarico Palma, Mario Sergio [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Costa-Lotufo, Leticia Veras Colepicolo, Pio Pupo, Mônica Tallarico Palma, Mario Sergio [UNESP] |
dc.subject.por.fl_str_mv |
arthropods bioeconomy biological active compounds insects microbiota Natural products |
topic |
arthropods bioeconomy biological active compounds insects microbiota Natural products |
description |
The present review aims the discussion of the impact of the bioprospection initiative developed by the projects associated to BIOprospecTA, a subprogram of the program BIOTA, supported by FAPESP. This review brings a summary of the main results produced by the projects investigating natural products (NPs) from non-plants organisms, as examples of the success of this initiative, focusing on the progresses achieved by the projects related to NPs from macroalgae, marine invertebrates, arthropods and associated microorganisms. Macroalgae are one of the most studied groups in Brazil with the isolation of many bioactive compounds including lipids, carotenoids, phycocolloids, lectins, mycosporine-like amino acids and halogenated compounds. Marine invertebrates and associated microorganisms have been more systematically studied in the last thirty years, revealing unique compounds, with potent biological activities. The venoms of Hymenopteran insects were also extensively studied, resulting in the identification of hundreds of peptides, which were used to create a chemical library that contributed for the identification of leader models for the development of antifungal, antiparasitic, and anticancer compounds. The built knowledge of Hymenopteran venoms permitted the development of an equine hyperimmune serum anti honeybee venom. Amongst the microorganisms associated with insects the bioprospecting strategy was to understand the molecular basis of intra-and interspecies interactions (Chemical Ecology), translating this knowledge to possible biotechnological applications. The results discussed here reinforce the importance of BIOprospecTA program on the development of research with highly innovative potential in Brazil. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-01-01 2023-03-02T10:44:16Z 2023-03-02T10:44:16Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/1676-0611-BN-2022-1345 Biota Neotropica, v. 22, n. Spe, 2022. 1676-0611 1676-0603 http://hdl.handle.net/11449/242167 10.1590/1676-0611-BN-2022-1345 2-s2.0-85136237782 |
url |
http://dx.doi.org/10.1590/1676-0611-BN-2022-1345 http://hdl.handle.net/11449/242167 |
identifier_str_mv |
Biota Neotropica, v. 22, n. Spe, 2022. 1676-0611 1676-0603 10.1590/1676-0611-BN-2022-1345 2-s2.0-85136237782 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Biota Neotropica |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799965298478022656 |