Bartonella spp. in households with cats: Risk factors for infection in cats and human exposure
Autor(a) principal: | |
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Data de Publicação: | 2023 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1016/j.onehlt.2023.100545 http://hdl.handle.net/11449/249880 |
Resumo: | The aim of this study was to estimate the occurrence of Bartonella spp. per household in cats and the risk factors for Bartonella spp. positivity in cats and their owners from Valdivia, Chile. A total of 464 cats (distributed within 324 households) and 326 humans (control group [n = 112] and cat owner [n = 214]) distributed in 262 households were sampled. From the cat owners (n = 214), 128 humans were in households where the cat was also sampled, totaling 84 households with dual sampling. Real-time PCR (qPCR) was used for Bartonella spp. detection in blood from cats and humans, and immunofluorescent immunoassay (IFA) anti-Bartonella henselae was performed in human serum samples. Out of the total of 324 households, 20.43% presented at least one Bartonella positive cat. From the households with dual sampling, 29.7% (25/84) presented at least one qPCR-Bartonella spp. positive cat. However, Bartonella DNA was not amplified in humans, and in 7.3% (6/82) of the households was found at least one of the cat's owners exposed to B. henselae. Cats younger than one year (Odds Ratio (OR) = 5.3), non-neutered (OR 3.46), sampled at home (OR 5.82), and with improper application of tick/flea control products (OR 3.13) showed a higher risk for Bartonella spp. presence. Humans with occupational exposure involving animal contact, were more likely to exhibit B. henselae seropositivity (OR 7.5). Bartonella spp. was present in the cats a moderate number of households, but Bartonella DNA was not detected in owners' blood, inferring that there is a low risk of recent human infection in the studied population. |
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Bartonella spp. in households with cats: Risk factors for infection in cats and human exposureBartonellosis.Cat-scratch diseaseOne health, felidsqPCRSerologyZoonosisThe aim of this study was to estimate the occurrence of Bartonella spp. per household in cats and the risk factors for Bartonella spp. positivity in cats and their owners from Valdivia, Chile. A total of 464 cats (distributed within 324 households) and 326 humans (control group [n = 112] and cat owner [n = 214]) distributed in 262 households were sampled. From the cat owners (n = 214), 128 humans were in households where the cat was also sampled, totaling 84 households with dual sampling. Real-time PCR (qPCR) was used for Bartonella spp. detection in blood from cats and humans, and immunofluorescent immunoassay (IFA) anti-Bartonella henselae was performed in human serum samples. Out of the total of 324 households, 20.43% presented at least one Bartonella positive cat. From the households with dual sampling, 29.7% (25/84) presented at least one qPCR-Bartonella spp. positive cat. However, Bartonella DNA was not amplified in humans, and in 7.3% (6/82) of the households was found at least one of the cat's owners exposed to B. henselae. Cats younger than one year (Odds Ratio (OR) = 5.3), non-neutered (OR 3.46), sampled at home (OR 5.82), and with improper application of tick/flea control products (OR 3.13) showed a higher risk for Bartonella spp. presence. Humans with occupational exposure involving animal contact, were more likely to exhibit B. henselae seropositivity (OR 7.5). Bartonella spp. was present in the cats a moderate number of households, but Bartonella DNA was not detected in owners' blood, inferring that there is a low risk of recent human infection in the studied population.Escuela de Graduados Facultad de Ciencias Veterinarias Universidad Austral de ChileInstituto de Medicina Preventiva Veterinaria Universidad Austral de ChileDepartment of Pathology Reproduction and One Health São Paulo State University (UNESP)Instituto de Ciencias Clínicas Veterinaria Universidad Austral de ChileInstituto de Bioquímica y Microbiología Universidad Austral de ChileOne Health Center for Zoonoses and Tropical Veterinary Medicine Department of Biomedical Sciences Ross University School of Veterinary MedicineQuantitative Veterinary Epidemiology Wageningen University & ResearchDepartment of Pathology Reproduction and One Health São Paulo State University (UNESP)Universidad Austral de ChileUniversidade Estadual Paulista (UNESP)Ross University School of Veterinary MedicineWageningen University & ResearchSepúlveda-García, PaulinaAlabi, Amir [UNESP]Álvarez, KarlaRojas, LisbethMella, ArminGonçalves, Luiz Ricardo [UNESP]André, Marcos Rogerio [UNESP]Machado, Rosangela Zacarias [UNESP]Müller, AnandaMonti, Gustavo2023-07-29T16:11:48Z2023-07-29T16:11:48Z2023-06-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1016/j.onehlt.2023.100545One Health, v. 16.2352-7714http://hdl.handle.net/11449/24988010.1016/j.onehlt.2023.1005452-s2.0-85153190630Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengOne Healthinfo:eu-repo/semantics/openAccess2023-07-29T16:11:48Zoai:repositorio.unesp.br:11449/249880Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-07-29T16:11:48Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Bartonella spp. in households with cats: Risk factors for infection in cats and human exposure |
title |
Bartonella spp. in households with cats: Risk factors for infection in cats and human exposure |
spellingShingle |
Bartonella spp. in households with cats: Risk factors for infection in cats and human exposure Sepúlveda-García, Paulina Bartonellosis. Cat-scratch disease One health, felids qPCR Serology Zoonosis |
title_short |
Bartonella spp. in households with cats: Risk factors for infection in cats and human exposure |
title_full |
Bartonella spp. in households with cats: Risk factors for infection in cats and human exposure |
title_fullStr |
Bartonella spp. in households with cats: Risk factors for infection in cats and human exposure |
title_full_unstemmed |
Bartonella spp. in households with cats: Risk factors for infection in cats and human exposure |
title_sort |
Bartonella spp. in households with cats: Risk factors for infection in cats and human exposure |
author |
Sepúlveda-García, Paulina |
author_facet |
Sepúlveda-García, Paulina Alabi, Amir [UNESP] Álvarez, Karla Rojas, Lisbeth Mella, Armin Gonçalves, Luiz Ricardo [UNESP] André, Marcos Rogerio [UNESP] Machado, Rosangela Zacarias [UNESP] Müller, Ananda Monti, Gustavo |
author_role |
author |
author2 |
Alabi, Amir [UNESP] Álvarez, Karla Rojas, Lisbeth Mella, Armin Gonçalves, Luiz Ricardo [UNESP] André, Marcos Rogerio [UNESP] Machado, Rosangela Zacarias [UNESP] Müller, Ananda Monti, Gustavo |
author2_role |
author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidad Austral de Chile Universidade Estadual Paulista (UNESP) Ross University School of Veterinary Medicine Wageningen University & Research |
dc.contributor.author.fl_str_mv |
Sepúlveda-García, Paulina Alabi, Amir [UNESP] Álvarez, Karla Rojas, Lisbeth Mella, Armin Gonçalves, Luiz Ricardo [UNESP] André, Marcos Rogerio [UNESP] Machado, Rosangela Zacarias [UNESP] Müller, Ananda Monti, Gustavo |
dc.subject.por.fl_str_mv |
Bartonellosis. Cat-scratch disease One health, felids qPCR Serology Zoonosis |
topic |
Bartonellosis. Cat-scratch disease One health, felids qPCR Serology Zoonosis |
description |
The aim of this study was to estimate the occurrence of Bartonella spp. per household in cats and the risk factors for Bartonella spp. positivity in cats and their owners from Valdivia, Chile. A total of 464 cats (distributed within 324 households) and 326 humans (control group [n = 112] and cat owner [n = 214]) distributed in 262 households were sampled. From the cat owners (n = 214), 128 humans were in households where the cat was also sampled, totaling 84 households with dual sampling. Real-time PCR (qPCR) was used for Bartonella spp. detection in blood from cats and humans, and immunofluorescent immunoassay (IFA) anti-Bartonella henselae was performed in human serum samples. Out of the total of 324 households, 20.43% presented at least one Bartonella positive cat. From the households with dual sampling, 29.7% (25/84) presented at least one qPCR-Bartonella spp. positive cat. However, Bartonella DNA was not amplified in humans, and in 7.3% (6/82) of the households was found at least one of the cat's owners exposed to B. henselae. Cats younger than one year (Odds Ratio (OR) = 5.3), non-neutered (OR 3.46), sampled at home (OR 5.82), and with improper application of tick/flea control products (OR 3.13) showed a higher risk for Bartonella spp. presence. Humans with occupational exposure involving animal contact, were more likely to exhibit B. henselae seropositivity (OR 7.5). Bartonella spp. was present in the cats a moderate number of households, but Bartonella DNA was not detected in owners' blood, inferring that there is a low risk of recent human infection in the studied population. |
publishDate |
2023 |
dc.date.none.fl_str_mv |
2023-07-29T16:11:48Z 2023-07-29T16:11:48Z 2023-06-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1016/j.onehlt.2023.100545 One Health, v. 16. 2352-7714 http://hdl.handle.net/11449/249880 10.1016/j.onehlt.2023.100545 2-s2.0-85153190630 |
url |
http://dx.doi.org/10.1016/j.onehlt.2023.100545 http://hdl.handle.net/11449/249880 |
identifier_str_mv |
One Health, v. 16. 2352-7714 10.1016/j.onehlt.2023.100545 2-s2.0-85153190630 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
One Health |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799965440599916544 |