Genomic data as the hitchhiker's guide to cattle adaptation: tracking the milestones of past selection in the bovine genome
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3389/fgene.2015.00036 http://hdl.handle.net/11449/131306 |
Resumo: | The bovine species have witnessed and played a major role in the drastic socio-economical changes that shaped our culture over the last 10,000 years. During this journey, cattle hitchhiked on human development and colonized the world, facing strong selective pressures such as dramatic environmental changes and disease challenge. Consequently, hundreds of specialized cattle breeds emerged and spread around the globe, making up a rich spectrum of genomic resources. Their DNA still carry the scars left from adapting to this wide range of conditions, and we are now empowered with data and analytical tools to track the milestones of past selection in their genomes. In this review paper, we provide a summary of the reconstructed demographic events that shaped cattle diversity, offer a critical synthesis of popular methodologies applied to the search for signatures of selection (SS) in genomic data, and give examples of recent SS studies in cattle. Then, we outline the potential and challenges of the application of SS analysis in cattle, and discuss the future directions in this field. |
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Genomic data as the hitchhiker's guide to cattle adaptation: tracking the milestones of past selection in the bovine genomeBos indicusBos taurusAdaptationPositive selectionSingle nucleotide polymorphismThe bovine species have witnessed and played a major role in the drastic socio-economical changes that shaped our culture over the last 10,000 years. During this journey, cattle hitchhiked on human development and colonized the world, facing strong selective pressures such as dramatic environmental changes and disease challenge. Consequently, hundreds of specialized cattle breeds emerged and spread around the globe, making up a rich spectrum of genomic resources. Their DNA still carry the scars left from adapting to this wide range of conditions, and we are now empowered with data and analytical tools to track the milestones of past selection in their genomes. In this review paper, we provide a summary of the reconstructed demographic events that shaped cattle diversity, offer a critical synthesis of popular methodologies applied to the search for signatures of selection (SS) in genomic data, and give examples of recent SS studies in cattle. Then, we outline the potential and challenges of the application of SS analysis in cattle, and discuss the future directions in this field.Departamento de Medicina Veterinária Preventiva e Reprodução Animal, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista (UNESP) Jaboticabal, São Paulo, Brazil.Division of Livestock Sciences, Department of Sustainable Agricultural Systems, University of Natural Resources and Life Sciences (BOKU) Vienna, Austria.Animal Genomics and Improvement Laboratory, Agricultural Research Service, United States Department of Agriculture Beltsville, MA, USA.Departamento de Medicina Veterinária Preventiva e Reprodução Animal, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista (UNESP) Jaboticabal, São Paulo, Brazil ; Laboratório de Bioquímica e Biologia Molecular Animal, Departamento de Apoio, Saúde e Produção Animal, Faculdade de Medicina Veterinária de Araçatuba, Universidade Estadual Paulista (UNESP) Araçatuba, São Paulo, Brazil.Departamento de Medicina Veterinária Preventiva e Reprodução Animal, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista (UNESP) Jaboticabal, São Paulo, Brazil.Departamento de Medicina Veterinária Preventiva e Reprodução Animal, Faculdade de Ciências Agrárias e Veterinárias, Universidade Estadual Paulista (UNESP) Jaboticabal, São Paulo, Brazil ; Laboratório de Bioquímica e Biologia Molecular Animal, Departamento de Apoio, Saúde e Produção Animal, Faculdade de Medicina Veterinária de Araçatuba, Universidade Estadual Paulista (UNESP) Araçatuba, São Paulo, Brazil.Frontiers In GeneticsUniversidade Estadual Paulista (Unesp)Division of Livestock Sciences, Department of Sustainable Agricultural Systems, University of Natural Resources and Life Sciences (BOKU) Vienna, Austria.Animal Genomics and Improvement Laboratory, Agricultural Research Service, United States Department of Agriculture Beltsville, MA, USA.Utsunomiya, Yuri T. [UNESP]Pérez O'Brien, Ana M.Sonstegard, Tad S.Sölkner, JohannGarcia, José F. [UNESP]2015-12-07T15:33:40Z2015-12-07T15:33:40Z2015info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article36application/pdfhttp://dx.doi.org/10.3389/fgene.2015.00036Frontiers In Genetics, v. 6, p. 36, 2015.1664-8021http://hdl.handle.net/11449/13130610.3389/fgene.2015.00036PMC4322753.pdf25713583PMC4322753PubMedreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengFrontiers In Genetics4.1512,274info:eu-repo/semantics/openAccess2024-01-13T06:37:55Zoai:repositorio.unesp.br:11449/131306Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-01-13T06:37:55Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Genomic data as the hitchhiker's guide to cattle adaptation: tracking the milestones of past selection in the bovine genome |
title |
Genomic data as the hitchhiker's guide to cattle adaptation: tracking the milestones of past selection in the bovine genome |
spellingShingle |
Genomic data as the hitchhiker's guide to cattle adaptation: tracking the milestones of past selection in the bovine genome Utsunomiya, Yuri T. [UNESP] Bos indicus Bos taurus Adaptation Positive selection Single nucleotide polymorphism |
title_short |
Genomic data as the hitchhiker's guide to cattle adaptation: tracking the milestones of past selection in the bovine genome |
title_full |
Genomic data as the hitchhiker's guide to cattle adaptation: tracking the milestones of past selection in the bovine genome |
title_fullStr |
Genomic data as the hitchhiker's guide to cattle adaptation: tracking the milestones of past selection in the bovine genome |
title_full_unstemmed |
Genomic data as the hitchhiker's guide to cattle adaptation: tracking the milestones of past selection in the bovine genome |
title_sort |
Genomic data as the hitchhiker's guide to cattle adaptation: tracking the milestones of past selection in the bovine genome |
author |
Utsunomiya, Yuri T. [UNESP] |
author_facet |
Utsunomiya, Yuri T. [UNESP] Pérez O'Brien, Ana M. Sonstegard, Tad S. Sölkner, Johann Garcia, José F. [UNESP] |
author_role |
author |
author2 |
Pérez O'Brien, Ana M. Sonstegard, Tad S. Sölkner, Johann Garcia, José F. [UNESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Division of Livestock Sciences, Department of Sustainable Agricultural Systems, University of Natural Resources and Life Sciences (BOKU) Vienna, Austria. Animal Genomics and Improvement Laboratory, Agricultural Research Service, United States Department of Agriculture Beltsville, MA, USA. |
dc.contributor.author.fl_str_mv |
Utsunomiya, Yuri T. [UNESP] Pérez O'Brien, Ana M. Sonstegard, Tad S. Sölkner, Johann Garcia, José F. [UNESP] |
dc.subject.por.fl_str_mv |
Bos indicus Bos taurus Adaptation Positive selection Single nucleotide polymorphism |
topic |
Bos indicus Bos taurus Adaptation Positive selection Single nucleotide polymorphism |
description |
The bovine species have witnessed and played a major role in the drastic socio-economical changes that shaped our culture over the last 10,000 years. During this journey, cattle hitchhiked on human development and colonized the world, facing strong selective pressures such as dramatic environmental changes and disease challenge. Consequently, hundreds of specialized cattle breeds emerged and spread around the globe, making up a rich spectrum of genomic resources. Their DNA still carry the scars left from adapting to this wide range of conditions, and we are now empowered with data and analytical tools to track the milestones of past selection in their genomes. In this review paper, we provide a summary of the reconstructed demographic events that shaped cattle diversity, offer a critical synthesis of popular methodologies applied to the search for signatures of selection (SS) in genomic data, and give examples of recent SS studies in cattle. Then, we outline the potential and challenges of the application of SS analysis in cattle, and discuss the future directions in this field. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-12-07T15:33:40Z 2015-12-07T15:33:40Z 2015 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3389/fgene.2015.00036 Frontiers In Genetics, v. 6, p. 36, 2015. 1664-8021 http://hdl.handle.net/11449/131306 10.3389/fgene.2015.00036 PMC4322753.pdf 25713583 PMC4322753 |
url |
http://dx.doi.org/10.3389/fgene.2015.00036 http://hdl.handle.net/11449/131306 |
identifier_str_mv |
Frontiers In Genetics, v. 6, p. 36, 2015. 1664-8021 10.3389/fgene.2015.00036 PMC4322753.pdf 25713583 PMC4322753 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Frontiers In Genetics 4.151 2,274 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
36 application/pdf |
dc.publisher.none.fl_str_mv |
Frontiers In Genetics |
publisher.none.fl_str_mv |
Frontiers In Genetics |
dc.source.none.fl_str_mv |
PubMed reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1799965608761098240 |