Clinical and morphological evaluation of snake venom derived fibrin glue on the tendon healing in dogs

Detalhes bibliográficos
Autor(a) principal: Ferraro, G. C. [UNESP]
Data de Publicação: 2005
Outros Autores: Moraes, J. R. E. [UNESP], Pereira, G. T. [UNESP], Moraes, F. R. [UNESP], Bueno De Camargo, M. H. [UNESP]
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://dx.doi.org/10.1590/S1678-91992005000400005
http://hdl.handle.net/11449/211861
Resumo: The aim of this study was to evaluate the effect of snake venom derived fibrin glue on the healing of the deep digital flexor tendon, during three periods. The tendon of the 2nd digit of 30 thoracic limbs of dogs was partially sectioned for glue application. Biopsies were performed 7, 15, and 30 days post surgery for the clinical and morphological study of tendons. Analysis of the results showed that 73.3% of the tendons showed stump retraction and 16.6% moderate to excessive adherence, which affected sliding. There was a significant difference in the number of inflammatory cells among the three studied periods, being the highest on day 15. The morphological analysis revealed a typical tendon healing process with a lower level of inflammation in the acute phase, facilitating the cicatricial maturation phase. Snake venom derived fibrin glue promotes the healing in dog flexor tendon.
id UNSP_a7750b7b3a56d91b70c712dc4ee9807c
oai_identifier_str oai:repositorio.unesp.br:11449/211861
network_acronym_str UNSP
network_name_str Repositório Institucional da UNESP
repository_id_str 2946
spelling Clinical and morphological evaluation of snake venom derived fibrin glue on the tendon healing in dogsdogfibrin gluesnake venomhealingtendonThe aim of this study was to evaluate the effect of snake venom derived fibrin glue on the healing of the deep digital flexor tendon, during three periods. The tendon of the 2nd digit of 30 thoracic limbs of dogs was partially sectioned for glue application. Biopsies were performed 7, 15, and 30 days post surgery for the clinical and morphological study of tendons. Analysis of the results showed that 73.3% of the tendons showed stump retraction and 16.6% moderate to excessive adherence, which affected sliding. There was a significant difference in the number of inflammatory cells among the three studied periods, being the highest on day 15. The morphological analysis revealed a typical tendon healing process with a lower level of inflammation in the acute phase, facilitating the cicatricial maturation phase. Snake venom derived fibrin glue promotes the healing in dog flexor tendon.Universidade Estadual Paulista, School of Agrarian and Veterinary SciencesUniversidade Estadual Paulista, School of Agrarian and Veterinary SciencesCentro de Estudos de Venenos e Animais PeçonhentosUniversidade Estadual Paulista (Unesp)Ferraro, G. C. [UNESP]Moraes, J. R. E. [UNESP]Pereira, G. T. [UNESP]Moraes, F. R. [UNESP]Bueno De Camargo, M. H. [UNESP]2021-07-14T10:30:45Z2021-07-14T10:30:45Z2005-12info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article433-446application/pdfhttp://dx.doi.org/10.1590/S1678-91992005000400005Journal of Venomous Animals and Toxins including Tropical Diseases. Botucatu, SP, Brazil: Centro de Estudos de Venenos e Animais Peçonhentos, v. 11, n. 4, p. 433-446, 2005.1678-9199http://hdl.handle.net/11449/21186110.1590/S1678-91992005000400005S1678-91992005000400005S1678-91992005000400005.pdfSciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Venomous Animals and Toxins including Tropical Diseasesinfo:eu-repo/semantics/openAccess2023-11-14T06:08:40Zoai:repositorio.unesp.br:11449/211861Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-11-14T06:08:40Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Clinical and morphological evaluation of snake venom derived fibrin glue on the tendon healing in dogs
title Clinical and morphological evaluation of snake venom derived fibrin glue on the tendon healing in dogs
spellingShingle Clinical and morphological evaluation of snake venom derived fibrin glue on the tendon healing in dogs
Ferraro, G. C. [UNESP]
dog
fibrin glue
snake venom
healing
tendon
title_short Clinical and morphological evaluation of snake venom derived fibrin glue on the tendon healing in dogs
title_full Clinical and morphological evaluation of snake venom derived fibrin glue on the tendon healing in dogs
title_fullStr Clinical and morphological evaluation of snake venom derived fibrin glue on the tendon healing in dogs
title_full_unstemmed Clinical and morphological evaluation of snake venom derived fibrin glue on the tendon healing in dogs
title_sort Clinical and morphological evaluation of snake venom derived fibrin glue on the tendon healing in dogs
author Ferraro, G. C. [UNESP]
author_facet Ferraro, G. C. [UNESP]
Moraes, J. R. E. [UNESP]
Pereira, G. T. [UNESP]
Moraes, F. R. [UNESP]
Bueno De Camargo, M. H. [UNESP]
author_role author
author2 Moraes, J. R. E. [UNESP]
Pereira, G. T. [UNESP]
Moraes, F. R. [UNESP]
Bueno De Camargo, M. H. [UNESP]
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade Estadual Paulista (Unesp)
dc.contributor.author.fl_str_mv Ferraro, G. C. [UNESP]
Moraes, J. R. E. [UNESP]
Pereira, G. T. [UNESP]
Moraes, F. R. [UNESP]
Bueno De Camargo, M. H. [UNESP]
dc.subject.por.fl_str_mv dog
fibrin glue
snake venom
healing
tendon
topic dog
fibrin glue
snake venom
healing
tendon
description The aim of this study was to evaluate the effect of snake venom derived fibrin glue on the healing of the deep digital flexor tendon, during three periods. The tendon of the 2nd digit of 30 thoracic limbs of dogs was partially sectioned for glue application. Biopsies were performed 7, 15, and 30 days post surgery for the clinical and morphological study of tendons. Analysis of the results showed that 73.3% of the tendons showed stump retraction and 16.6% moderate to excessive adherence, which affected sliding. There was a significant difference in the number of inflammatory cells among the three studied periods, being the highest on day 15. The morphological analysis revealed a typical tendon healing process with a lower level of inflammation in the acute phase, facilitating the cicatricial maturation phase. Snake venom derived fibrin glue promotes the healing in dog flexor tendon.
publishDate 2005
dc.date.none.fl_str_mv 2005-12
2021-07-14T10:30:45Z
2021-07-14T10:30:45Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://dx.doi.org/10.1590/S1678-91992005000400005
Journal of Venomous Animals and Toxins including Tropical Diseases. Botucatu, SP, Brazil: Centro de Estudos de Venenos e Animais Peçonhentos, v. 11, n. 4, p. 433-446, 2005.
1678-9199
http://hdl.handle.net/11449/211861
10.1590/S1678-91992005000400005
S1678-91992005000400005
S1678-91992005000400005.pdf
url http://dx.doi.org/10.1590/S1678-91992005000400005
http://hdl.handle.net/11449/211861
identifier_str_mv Journal of Venomous Animals and Toxins including Tropical Diseases. Botucatu, SP, Brazil: Centro de Estudos de Venenos e Animais Peçonhentos, v. 11, n. 4, p. 433-446, 2005.
1678-9199
10.1590/S1678-91992005000400005
S1678-91992005000400005
S1678-91992005000400005.pdf
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Journal of Venomous Animals and Toxins including Tropical Diseases
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 433-446
application/pdf
dc.publisher.none.fl_str_mv Centro de Estudos de Venenos e Animais Peçonhentos
publisher.none.fl_str_mv Centro de Estudos de Venenos e Animais Peçonhentos
dc.source.none.fl_str_mv SciELO
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
_version_ 1799964926475763712

Registros relacionados