Radiographic assessment of potodynamic therapy as an adjunctive treatment on induced periodontitis in immunosupressed rats
Autor(a) principal: | |
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Data de Publicação: | 2010 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/S1678-77572010000300007 http://hdl.handle.net/11449/133142 |
Resumo: | OBJECTIVE: The aim of this study was to assess radiographically the effect of photodynamic therapy (PDT) as an adjunctive treatment to scaling and root planing (SRP) on induced periodontitis in dexamethasone-induced immunosuppressed rats. MATERIAL AND METHODS: The animals were divided into 2 groups: ND group (n=60): saline treatment; D group (n=60): dexamethasone treatment. In both ND and D groups, periodontal disease was induced by the placement of a ligature in the left first mandibular molar. After 7 days, ligature was removed and all animals received SRP, being divided according to the following treatments: SRP: saline and PDT: phenothiazinium dye (TBO) plus laser irradiation. Ten animals per treatment were killed at 7, 15 and 30 days. The distance between the cementoenamel junction and the height of the alveolar bone crest in the mesial surface of the mandibular left first molars was determined in millimeters in each radiograph. he radiographic values were analyzed statistically by ANOVA and Tukey's test at a p value <0.05. RESULTS: Intragroup radiographic assessment (ND and D groups) showed that there was statistically signifcant less bone loss in the animals treated with PDT in all experimental periods compared to those submitted to SRP. Intergroup radiographic analysis (ND and D groups) demonstrated that there was greater bone loss in the ND group treated with SRP compared to the D group treated with PDT at 7 and 30 days. CONCLUSION: PDT was an effective adjunctive treatment to SRP on induced periodontitis in dexamethasone-induced immunosuppressed rats. |
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Radiographic assessment of potodynamic therapy as an adjunctive treatment on induced periodontitis in immunosupressed ratsPeriodontitisLaserDexamethasoneRatsCorticosteroidsOBJECTIVE: The aim of this study was to assess radiographically the effect of photodynamic therapy (PDT) as an adjunctive treatment to scaling and root planing (SRP) on induced periodontitis in dexamethasone-induced immunosuppressed rats. MATERIAL AND METHODS: The animals were divided into 2 groups: ND group (n=60): saline treatment; D group (n=60): dexamethasone treatment. In both ND and D groups, periodontal disease was induced by the placement of a ligature in the left first mandibular molar. After 7 days, ligature was removed and all animals received SRP, being divided according to the following treatments: SRP: saline and PDT: phenothiazinium dye (TBO) plus laser irradiation. Ten animals per treatment were killed at 7, 15 and 30 days. The distance between the cementoenamel junction and the height of the alveolar bone crest in the mesial surface of the mandibular left first molars was determined in millimeters in each radiograph. he radiographic values were analyzed statistically by ANOVA and Tukey's test at a p value <0.05. RESULTS: Intragroup radiographic assessment (ND and D groups) showed that there was statistically signifcant less bone loss in the animals treated with PDT in all experimental periods compared to those submitted to SRP. Intergroup radiographic analysis (ND and D groups) demonstrated that there was greater bone loss in the ND group treated with SRP compared to the D group treated with PDT at 7 and 30 days. CONCLUSION: PDT was an effective adjunctive treatment to SRP on induced periodontitis in dexamethasone-induced immunosuppressed rats.Department of Pathology and Clinical Dentistry, Federal University of Piauí, PI, BrazilDepartment of Surgery and Integrated Clinic, Araçatuba Dental School, São Paulo State University, Araçatuba, SP, BrazilDepartment of Periodontics, University Center of Educational Foundation of Barretos, Barretos Dental School, Barretos, SP, BrazilDepartment of Surgery and Integrated Clinic, Araçatuba Dental School, São Paulo State University, Araçatuba, SP, BrazilUniversidade Estadual Paulista Júlio de Mesquita Filho, Faculdade de Odontologia de Araçatuba, Aracatuba, Rua José Bonifário, 1193, Vila Mendonça, CEP 16015-050, SP, Brasil, Department of Surgery and Integrated Clinic, Araçatuba Dental School, São Paulo State University, Araçatuba, SP, BrazilUniversidade Estadual Paulista (Unesp)Universidade Federal do Piauí (UFPI)Centro Universitário da Fundação Educacional de Barretos (UNIFEB)Fernandes, Leandro AraujoMartins, Thiago Marchi [UNESP]Almeida, Juliano Milanezi de [UNESP]Theodoro, Letícia HelenaGarcia, Valdir Gouveia [UNESP]2016-01-28T16:53:49Z2016-01-28T16:53:49Z2010info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article237-243application/pdfhttp://dx.doi.org/10.1590/S1678-77572010000300007Journal of Applied Oral Science, v. 18, n. 3, p. 237-243, 2010.1678-7757http://hdl.handle.net/11449/13314210.1590/S1678-77572010000300007S1678-77572010000300007S1678-77572010000300007.pdf004706219353419047744471181273464068921369233125Currículo Lattesreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengJournal of Applied Oral Science1.7090,645info:eu-repo/semantics/openAccess2023-10-04T06:08:55Zoai:repositorio.unesp.br:11449/133142Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-10-04T06:08:55Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Radiographic assessment of potodynamic therapy as an adjunctive treatment on induced periodontitis in immunosupressed rats |
title |
Radiographic assessment of potodynamic therapy as an adjunctive treatment on induced periodontitis in immunosupressed rats |
spellingShingle |
Radiographic assessment of potodynamic therapy as an adjunctive treatment on induced periodontitis in immunosupressed rats Fernandes, Leandro Araujo Periodontitis Laser Dexamethasone Rats Corticosteroids |
title_short |
Radiographic assessment of potodynamic therapy as an adjunctive treatment on induced periodontitis in immunosupressed rats |
title_full |
Radiographic assessment of potodynamic therapy as an adjunctive treatment on induced periodontitis in immunosupressed rats |
title_fullStr |
Radiographic assessment of potodynamic therapy as an adjunctive treatment on induced periodontitis in immunosupressed rats |
title_full_unstemmed |
Radiographic assessment of potodynamic therapy as an adjunctive treatment on induced periodontitis in immunosupressed rats |
title_sort |
Radiographic assessment of potodynamic therapy as an adjunctive treatment on induced periodontitis in immunosupressed rats |
author |
Fernandes, Leandro Araujo |
author_facet |
Fernandes, Leandro Araujo Martins, Thiago Marchi [UNESP] Almeida, Juliano Milanezi de [UNESP] Theodoro, Letícia Helena Garcia, Valdir Gouveia [UNESP] |
author_role |
author |
author2 |
Martins, Thiago Marchi [UNESP] Almeida, Juliano Milanezi de [UNESP] Theodoro, Letícia Helena Garcia, Valdir Gouveia [UNESP] |
author2_role |
author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade Federal do Piauí (UFPI) Centro Universitário da Fundação Educacional de Barretos (UNIFEB) |
dc.contributor.author.fl_str_mv |
Fernandes, Leandro Araujo Martins, Thiago Marchi [UNESP] Almeida, Juliano Milanezi de [UNESP] Theodoro, Letícia Helena Garcia, Valdir Gouveia [UNESP] |
dc.subject.por.fl_str_mv |
Periodontitis Laser Dexamethasone Rats Corticosteroids |
topic |
Periodontitis Laser Dexamethasone Rats Corticosteroids |
description |
OBJECTIVE: The aim of this study was to assess radiographically the effect of photodynamic therapy (PDT) as an adjunctive treatment to scaling and root planing (SRP) on induced periodontitis in dexamethasone-induced immunosuppressed rats. MATERIAL AND METHODS: The animals were divided into 2 groups: ND group (n=60): saline treatment; D group (n=60): dexamethasone treatment. In both ND and D groups, periodontal disease was induced by the placement of a ligature in the left first mandibular molar. After 7 days, ligature was removed and all animals received SRP, being divided according to the following treatments: SRP: saline and PDT: phenothiazinium dye (TBO) plus laser irradiation. Ten animals per treatment were killed at 7, 15 and 30 days. The distance between the cementoenamel junction and the height of the alveolar bone crest in the mesial surface of the mandibular left first molars was determined in millimeters in each radiograph. he radiographic values were analyzed statistically by ANOVA and Tukey's test at a p value <0.05. RESULTS: Intragroup radiographic assessment (ND and D groups) showed that there was statistically signifcant less bone loss in the animals treated with PDT in all experimental periods compared to those submitted to SRP. Intergroup radiographic analysis (ND and D groups) demonstrated that there was greater bone loss in the ND group treated with SRP compared to the D group treated with PDT at 7 and 30 days. CONCLUSION: PDT was an effective adjunctive treatment to SRP on induced periodontitis in dexamethasone-induced immunosuppressed rats. |
publishDate |
2010 |
dc.date.none.fl_str_mv |
2010 2016-01-28T16:53:49Z 2016-01-28T16:53:49Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S1678-77572010000300007 Journal of Applied Oral Science, v. 18, n. 3, p. 237-243, 2010. 1678-7757 http://hdl.handle.net/11449/133142 10.1590/S1678-77572010000300007 S1678-77572010000300007 S1678-77572010000300007.pdf 0047062193534190 4774447118127346 4068921369233125 |
url |
http://dx.doi.org/10.1590/S1678-77572010000300007 http://hdl.handle.net/11449/133142 |
identifier_str_mv |
Journal of Applied Oral Science, v. 18, n. 3, p. 237-243, 2010. 1678-7757 10.1590/S1678-77572010000300007 S1678-77572010000300007 S1678-77572010000300007.pdf 0047062193534190 4774447118127346 4068921369233125 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Journal of Applied Oral Science 1.709 0,645 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
237-243 application/pdf |
dc.source.none.fl_str_mv |
Currículo Lattes reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1797789292097961984 |