SECOND BRAZILIAN CONSENSUS ON THE MANAGEMENT OF CROHN'S DISEASE IN ADULTS: A CONSENSUS OF THE BRAZILIAN ORGANIZATION FOR CROHN'S DISEASE AND COLITIS (GEDIIB)

• Autor(a) principal: Imbrizi, Marcello
• Data de Publicação: 2023
• Outros Autores: Baima, Júlio Pinheiro [UNESP], Azevedo, Matheus Freitas Cardoso de [UNESP], Andrade, Adriana Ribas, Queiroz, Natália Souza Freitas, Chebli, Júlio Maria Fonseca, Chebli, Liliane Andrade, Argollo, Marjorie Costa, Sassaki, Ligia Yukie [UNESP], Parra, Rogerio Serafim, Quaresma, Abel Botelho, Vieira, Andrea, Damião, Adérson Omar Mourão Cintra [UNESP], Moraes, Antonio Carlos da Silva, Flores, Cristina, Zaltman, Cyrla, Vilela, Eduardo Garcia, Morsoletto, Eloá Marussi, Gonçalves Filho, Francisco de Assis, Penna, Francisco Guilherme Cancela E, Santana, Genoile Oliveira [UNESP], Zabot, Gilmara Pandolfo, Parente, José Miguel Luz, Costa, Marcia Henriques de Magalhães, Zerôncio, Marco Antonio, Machado, Marta Brenner, Cassol, Ornella Sari, Kotze, Paulo Gustavo, Fróes, Renata de Sá Brito, Miszputen, Sender Jankiel, Ambrogini Junior, Orlando, Saad-Hossne, Rogério, Coy, Cláudio Saddy Rodrigues
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.1590/S0004-2803.2022005S1-02; http://hdl.handle.net/11449/248630

BACKGROUND: Inflammatory bowel disease (IBD) is an immune-mediated disorder that includes Crohn's disease (CD) and ulcerative colitis. CD is characterized by a transmural intestinal involvement from the mouth to the anus with recurrent and remitting symptoms that can lead to progressive bowel damage and disability over time. OBJECTIVE: To guide the safest and effective medical treatments of adults with CD. METHODS: This consensus was developed by stakeholders representing Brazilian gastroenterologists and colorectal surgeons (Brazilian Organization for Crohn's disease and Colitis (GEDIIB)). A systematic review of the most recent evidence was conducted to support the recommendations/statements. All included recommendations and statements were endorsed in a modified Delphi panel by the stakeholders and experts in IBD with an agreement of at least 80% or greater consensus rate. RESULTS AND CONCLUSION: The medical recommendations (pharmacological and non-pharmacological interventions) were mapped according to the stage of treatment and severity of the disease in three domains: management and treatment (drug and surgical interventions), criteria for evaluating the effectiveness of medical treatment, and follow-up/patient monitoring after initial treatment. The consensus is targeted towards general practitioners, gastroenterologists, and surgeons interested in treating and managing adults with CD and supports the decision-making of health insurance companies, regulatory agencies, and health institutional leaders or administrators.