Cissus quadrangularis (Linn) (Uva velve) and phyllanthus reticulatus poir (Linn) (Pancolin) in wound healing

Detalhes bibliográficos
Autor(a) principal: Charas Dos Santos, Ivan Felismino [UNESP]
Data de Publicação: 2015
Outros Autores: Nhambirre, André, Bata Bambo, Otilia [UNESP], Mota Cardoso, José Manuel [UNESP]
Tipo de documento: Artigo
Idioma: spa
Título da fonte: Repositório Institucional da UNESP
Texto Completo: http://hdl.handle.net/11449/220491
Resumo: Introduction: Cissus quadrangularis (Linn) has healing, analgesia and antiinflammatory effects. Phyllanthus reticulatus Poir (Linn) is used for treating skin wounds, burns and ulcers. Objectives: to compare the effectiveness of C. quandrangularis and P. reticulatus in wounds healing surgically induced in skin of guinea pigs, evaluating the healing time, microscopic and macroscopic healing variations and contamination degree. Methods: Was used in study 30 health guinea pigs, males, six months old, with mean weight of 650 grams. Three wounds were promoted in each animal in the dorsal region and the wound was treated, daily, with C. quandrangularis, saline solution 0.9% and with P. reticulatus. The biopsies were performed in Group I on the seventh day after the surgery, Group II on the fourteenth day and the Group III on the twenty-first day after the surgery and sent to histopathologycal evaluation. Results: on the seventh day of treatment the wounds which treated with C. quadrangularis were observed granulation tissue, while wounds treated with P. reticulatus were observed on the ninth day after. No healing significant difference occurred between the treatments. During the study was observed predominance of neutrophils in all wounds of all groups, more evident in those treated with C. quandrangularis. Conclusion: The wounds which treated with C. quandrangularis healed faster and showed less contamination degree than treated with P. reticulatus.
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spelling Cissus quadrangularis (Linn) (Uva velve) and phyllanthus reticulatus poir (Linn) (Pancolin) in wound healingCissus quadrangularis (Linn) (Uva Velve) y Phyllanthus reticulatus Poir (Linn) (Pancolin) en la cicatrización de heridasHealing evolutionPhitotherapySkin lesionIntroduction: Cissus quadrangularis (Linn) has healing, analgesia and antiinflammatory effects. Phyllanthus reticulatus Poir (Linn) is used for treating skin wounds, burns and ulcers. Objectives: to compare the effectiveness of C. quandrangularis and P. reticulatus in wounds healing surgically induced in skin of guinea pigs, evaluating the healing time, microscopic and macroscopic healing variations and contamination degree. Methods: Was used in study 30 health guinea pigs, males, six months old, with mean weight of 650 grams. Three wounds were promoted in each animal in the dorsal region and the wound was treated, daily, with C. quandrangularis, saline solution 0.9% and with P. reticulatus. The biopsies were performed in Group I on the seventh day after the surgery, Group II on the fourteenth day and the Group III on the twenty-first day after the surgery and sent to histopathologycal evaluation. Results: on the seventh day of treatment the wounds which treated with C. quadrangularis were observed granulation tissue, while wounds treated with P. reticulatus were observed on the ninth day after. No healing significant difference occurred between the treatments. During the study was observed predominance of neutrophils in all wounds of all groups, more evident in those treated with C. quandrangularis. Conclusion: The wounds which treated with C. quandrangularis healed faster and showed less contamination degree than treated with P. reticulatus.Universidad Eduardo MondlaneUniversidad Estadual PaulistaUniversidad Estadual PaulistaUniversidad Eduardo MondlaneUniversidade Estadual Paulista (UNESP)Charas Dos Santos, Ivan Felismino [UNESP]Nhambirre, AndréBata Bambo, Otilia [UNESP]Mota Cardoso, José Manuel [UNESP]2022-04-28T19:01:44Z2022-04-28T19:01:44Z2015-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article348-357Revista Cubana de Plantas Medicinales, v. 20, n. 3, p. 348-357, 2015.1028-4796http://hdl.handle.net/11449/2204912-s2.0-84946556099Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPspaRevista Cubana de Plantas Medicinalesinfo:eu-repo/semantics/openAccess2022-04-28T19:01:44Zoai:repositorio.unesp.br:11449/220491Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-08-05T13:47:59.278363Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false
dc.title.none.fl_str_mv Cissus quadrangularis (Linn) (Uva velve) and phyllanthus reticulatus poir (Linn) (Pancolin) in wound healing
Cissus quadrangularis (Linn) (Uva Velve) y Phyllanthus reticulatus Poir (Linn) (Pancolin) en la cicatrización de heridas
title Cissus quadrangularis (Linn) (Uva velve) and phyllanthus reticulatus poir (Linn) (Pancolin) in wound healing
spellingShingle Cissus quadrangularis (Linn) (Uva velve) and phyllanthus reticulatus poir (Linn) (Pancolin) in wound healing
Charas Dos Santos, Ivan Felismino [UNESP]
Healing evolution
Phitotherapy
Skin lesion
title_short Cissus quadrangularis (Linn) (Uva velve) and phyllanthus reticulatus poir (Linn) (Pancolin) in wound healing
title_full Cissus quadrangularis (Linn) (Uva velve) and phyllanthus reticulatus poir (Linn) (Pancolin) in wound healing
title_fullStr Cissus quadrangularis (Linn) (Uva velve) and phyllanthus reticulatus poir (Linn) (Pancolin) in wound healing
title_full_unstemmed Cissus quadrangularis (Linn) (Uva velve) and phyllanthus reticulatus poir (Linn) (Pancolin) in wound healing
title_sort Cissus quadrangularis (Linn) (Uva velve) and phyllanthus reticulatus poir (Linn) (Pancolin) in wound healing
author Charas Dos Santos, Ivan Felismino [UNESP]
author_facet Charas Dos Santos, Ivan Felismino [UNESP]
Nhambirre, André
Bata Bambo, Otilia [UNESP]
Mota Cardoso, José Manuel [UNESP]
author_role author
author2 Nhambirre, André
Bata Bambo, Otilia [UNESP]
Mota Cardoso, José Manuel [UNESP]
author2_role author
author
author
dc.contributor.none.fl_str_mv Universidad Eduardo Mondlane
Universidade Estadual Paulista (UNESP)
dc.contributor.author.fl_str_mv Charas Dos Santos, Ivan Felismino [UNESP]
Nhambirre, André
Bata Bambo, Otilia [UNESP]
Mota Cardoso, José Manuel [UNESP]
dc.subject.por.fl_str_mv Healing evolution
Phitotherapy
Skin lesion
topic Healing evolution
Phitotherapy
Skin lesion
description Introduction: Cissus quadrangularis (Linn) has healing, analgesia and antiinflammatory effects. Phyllanthus reticulatus Poir (Linn) is used for treating skin wounds, burns and ulcers. Objectives: to compare the effectiveness of C. quandrangularis and P. reticulatus in wounds healing surgically induced in skin of guinea pigs, evaluating the healing time, microscopic and macroscopic healing variations and contamination degree. Methods: Was used in study 30 health guinea pigs, males, six months old, with mean weight of 650 grams. Three wounds were promoted in each animal in the dorsal region and the wound was treated, daily, with C. quandrangularis, saline solution 0.9% and with P. reticulatus. The biopsies were performed in Group I on the seventh day after the surgery, Group II on the fourteenth day and the Group III on the twenty-first day after the surgery and sent to histopathologycal evaluation. Results: on the seventh day of treatment the wounds which treated with C. quadrangularis were observed granulation tissue, while wounds treated with P. reticulatus were observed on the ninth day after. No healing significant difference occurred between the treatments. During the study was observed predominance of neutrophils in all wounds of all groups, more evident in those treated with C. quandrangularis. Conclusion: The wounds which treated with C. quandrangularis healed faster and showed less contamination degree than treated with P. reticulatus.
publishDate 2015
dc.date.none.fl_str_mv 2015-07-01
2022-04-28T19:01:44Z
2022-04-28T19:01:44Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv Revista Cubana de Plantas Medicinales, v. 20, n. 3, p. 348-357, 2015.
1028-4796
http://hdl.handle.net/11449/220491
2-s2.0-84946556099
identifier_str_mv Revista Cubana de Plantas Medicinales, v. 20, n. 3, p. 348-357, 2015.
1028-4796
2-s2.0-84946556099
url http://hdl.handle.net/11449/220491
dc.language.iso.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv Revista Cubana de Plantas Medicinales
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 348-357
dc.source.none.fl_str_mv Scopus
reponame:Repositório Institucional da UNESP
instname:Universidade Estadual Paulista (UNESP)
instacron:UNESP
instname_str Universidade Estadual Paulista (UNESP)
instacron_str UNESP
institution UNESP
reponame_str Repositório Institucional da UNESP
collection Repositório Institucional da UNESP
repository.name.fl_str_mv Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)
repository.mail.fl_str_mv
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