Endodontic medicine: Interrelationships among apical periodontitis, systemic disorders, and tissue responses of dental materials
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/1807-3107bor-2018.vol32.0068 http://hdl.handle.net/11449/189839 |
Resumo: | Endodontic medicine, which addresses the bidirectional relationship between endodontic infections and systemic diseases, has gained prominence in the field of endodontics. There is much evidence showing that while systemic disease may influence the pathogenesis of endodontic infection, endodontic infection can also cause systemic alterations. These alterations include more severe bone resorption and inflammation in the periapical area as well as enhanced systemic disease symptoms. Similarly, many reports have described the impact of systemic diseases on the tissue responses to dental materials. Conversely, the local use of dental materials may show systemic effects in the form of altered production of biomarkers. Thus, studies to better understand the mechanisms related to those connections are extremely important. In this context, the objective of this review was to analyze and discuss the current literature regarding the connections among these three factors-systemic diseases, endodontic infection, and endodontic dental materials-and determine how these connections may interfere in the systemic health status and the endodontic treatment outcomes, which are represented by periapical wound healing. |
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Endodontic medicine: Interrelationships among apical periodontitis, systemic disorders, and tissue responses of dental materialsDental materialsDental pulp necrosisEndodonticsMetabolic diseasesPeriapical periodontitisEndodontic medicine, which addresses the bidirectional relationship between endodontic infections and systemic diseases, has gained prominence in the field of endodontics. There is much evidence showing that while systemic disease may influence the pathogenesis of endodontic infection, endodontic infection can also cause systemic alterations. These alterations include more severe bone resorption and inflammation in the periapical area as well as enhanced systemic disease symptoms. Similarly, many reports have described the impact of systemic diseases on the tissue responses to dental materials. Conversely, the local use of dental materials may show systemic effects in the form of altered production of biomarkers. Thus, studies to better understand the mechanisms related to those connections are extremely important. In this context, the objective of this review was to analyze and discuss the current literature regarding the connections among these three factors-systemic diseases, endodontic infection, and endodontic dental materials-and determine how these connections may interfere in the systemic health status and the endodontic treatment outcomes, which are represented by periapical wound healing.Universidade Estadual Paulista - Unesp School of Dentistry Department of EndodonticsUniversidade Federal de Goiás - UFG School of Dentistry Department of Stomatologic SciencesUniversity of Michigan Department of Cariology Restorative Sciences and EndodonticsNOVA Southeastern University College of Dental Medicine Department of PeriodontologyUniversidade Estadual Paulista - Unesp School of Dentistry Department of EndodonticsUniversidade Estadual Paulista (Unesp)Universidade Federal de Goiás (UFG)Restorative Sciences and EndodonticsNOVA Southeastern University College of Dental MedicineCintra, Luciano Tavares Angelo [UNESP]Estrela, CarlosAzuma, Mariane MaffeiQueiroz, índia Olinta de Azevedo [UNESP]Kawai, ToshihisaGomes-Filho, João Eduardo [UNESP]2019-10-06T16:53:51Z2019-10-06T16:53:51Z2018-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article66-81application/pdfhttp://dx.doi.org/10.1590/1807-3107bor-2018.vol32.0068Brazilian Oral Research, v. 32, p. 66-81.1807-31071806-8324http://hdl.handle.net/11449/18983910.1590/1807-3107bor-2018.vol32.0068S1806-832420180005006032-s2.0-85055617356S1806-83242018000500603.pdf9235743081667362Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengBrazilian Oral Researchinfo:eu-repo/semantics/openAccess2023-10-31T06:06:41Zoai:repositorio.unesp.br:11449/189839Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-10-31T06:06:41Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Endodontic medicine: Interrelationships among apical periodontitis, systemic disorders, and tissue responses of dental materials |
title |
Endodontic medicine: Interrelationships among apical periodontitis, systemic disorders, and tissue responses of dental materials |
spellingShingle |
Endodontic medicine: Interrelationships among apical periodontitis, systemic disorders, and tissue responses of dental materials Cintra, Luciano Tavares Angelo [UNESP] Dental materials Dental pulp necrosis Endodontics Metabolic diseases Periapical periodontitis |
title_short |
Endodontic medicine: Interrelationships among apical periodontitis, systemic disorders, and tissue responses of dental materials |
title_full |
Endodontic medicine: Interrelationships among apical periodontitis, systemic disorders, and tissue responses of dental materials |
title_fullStr |
Endodontic medicine: Interrelationships among apical periodontitis, systemic disorders, and tissue responses of dental materials |
title_full_unstemmed |
Endodontic medicine: Interrelationships among apical periodontitis, systemic disorders, and tissue responses of dental materials |
title_sort |
Endodontic medicine: Interrelationships among apical periodontitis, systemic disorders, and tissue responses of dental materials |
author |
Cintra, Luciano Tavares Angelo [UNESP] |
author_facet |
Cintra, Luciano Tavares Angelo [UNESP] Estrela, Carlos Azuma, Mariane Maffei Queiroz, índia Olinta de Azevedo [UNESP] Kawai, Toshihisa Gomes-Filho, João Eduardo [UNESP] |
author_role |
author |
author2 |
Estrela, Carlos Azuma, Mariane Maffei Queiroz, índia Olinta de Azevedo [UNESP] Kawai, Toshihisa Gomes-Filho, João Eduardo [UNESP] |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (Unesp) Universidade Federal de Goiás (UFG) Restorative Sciences and Endodontics NOVA Southeastern University College of Dental Medicine |
dc.contributor.author.fl_str_mv |
Cintra, Luciano Tavares Angelo [UNESP] Estrela, Carlos Azuma, Mariane Maffei Queiroz, índia Olinta de Azevedo [UNESP] Kawai, Toshihisa Gomes-Filho, João Eduardo [UNESP] |
dc.subject.por.fl_str_mv |
Dental materials Dental pulp necrosis Endodontics Metabolic diseases Periapical periodontitis |
topic |
Dental materials Dental pulp necrosis Endodontics Metabolic diseases Periapical periodontitis |
description |
Endodontic medicine, which addresses the bidirectional relationship between endodontic infections and systemic diseases, has gained prominence in the field of endodontics. There is much evidence showing that while systemic disease may influence the pathogenesis of endodontic infection, endodontic infection can also cause systemic alterations. These alterations include more severe bone resorption and inflammation in the periapical area as well as enhanced systemic disease symptoms. Similarly, many reports have described the impact of systemic diseases on the tissue responses to dental materials. Conversely, the local use of dental materials may show systemic effects in the form of altered production of biomarkers. Thus, studies to better understand the mechanisms related to those connections are extremely important. In this context, the objective of this review was to analyze and discuss the current literature regarding the connections among these three factors-systemic diseases, endodontic infection, and endodontic dental materials-and determine how these connections may interfere in the systemic health status and the endodontic treatment outcomes, which are represented by periapical wound healing. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-01-01 2019-10-06T16:53:51Z 2019-10-06T16:53:51Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/1807-3107bor-2018.vol32.0068 Brazilian Oral Research, v. 32, p. 66-81. 1807-3107 1806-8324 http://hdl.handle.net/11449/189839 10.1590/1807-3107bor-2018.vol32.0068 S1806-83242018000500603 2-s2.0-85055617356 S1806-83242018000500603.pdf 9235743081667362 |
url |
http://dx.doi.org/10.1590/1807-3107bor-2018.vol32.0068 http://hdl.handle.net/11449/189839 |
identifier_str_mv |
Brazilian Oral Research, v. 32, p. 66-81. 1807-3107 1806-8324 10.1590/1807-3107bor-2018.vol32.0068 S1806-83242018000500603 2-s2.0-85055617356 S1806-83242018000500603.pdf 9235743081667362 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Brazilian Oral Research |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
66-81 application/pdf |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799964763736768512 |