Effects of 48-hour feed deprivation on acute-phase response in horses
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/1809-6891v23e-72445E http://hdl.handle.net/11449/244859 |
Resumo: | The objective of this study was to evaluate the effect of feed restriction on acute-phase response in horses. Twenty horses were deprived of food for 48 h and others 12 animals (control) had free access to water and hay. They were closely monitored and examined, and blood samples were taken at the beginning (0) of the study and 6, 12, 18, 24, 30, 36, 42 and 48 hours afterward. Data were submitted to two-way analysis of variance with repeated measures and statistical significance was P ≤ 0.05. The horses tolerated feed restriction without serious clinical complications. Feed restriction induced an increase in the acute-phase response by elevating serum concentrations of α2-macroglobulin (24-38 h), ceruloplasmin (36-48 h), α1-antitrypsin (30-48 h), α1-acid glycoprotein (42-48 h) and haptoglobin (42-48 h). Nutrient deprivation raised the levels of circulating cortisol, which acts on the innate immune system, which then induces the acute-phase response. In conclusion, food restriction is a physical stressor for horses, capable of inducing an acute-phase protein reaction, characterized by increased production of α2-macroglobulin, ceruloplasmin, α1- antitrypsin, α1-acid glycoprotein and haptoglobin. |
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Effects of 48-hour feed deprivation on acute-phase response in horsesEquineFeed restrictionInflammationImmune responseProteinsStressThe objective of this study was to evaluate the effect of feed restriction on acute-phase response in horses. Twenty horses were deprived of food for 48 h and others 12 animals (control) had free access to water and hay. They were closely monitored and examined, and blood samples were taken at the beginning (0) of the study and 6, 12, 18, 24, 30, 36, 42 and 48 hours afterward. Data were submitted to two-way analysis of variance with repeated measures and statistical significance was P ≤ 0.05. The horses tolerated feed restriction without serious clinical complications. Feed restriction induced an increase in the acute-phase response by elevating serum concentrations of α2-macroglobulin (24-38 h), ceruloplasmin (36-48 h), α1-antitrypsin (30-48 h), α1-acid glycoprotein (42-48 h) and haptoglobin (42-48 h). Nutrient deprivation raised the levels of circulating cortisol, which acts on the innate immune system, which then induces the acute-phase response. In conclusion, food restriction is a physical stressor for horses, capable of inducing an acute-phase protein reaction, characterized by increased production of α2-macroglobulin, ceruloplasmin, α1- antitrypsin, α1-acid glycoprotein and haptoglobin.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF)Universidade Federal de Viçosa (UFV)Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)Universidade Estadual Paulista Júlio de Mesquita Filho (UNESP)CAPES: 001Universidade Federal de GoiásUniversidade Estadual do Norte Fluminense Darcy Ribeiro (UENF)Universidade Federal de Viçosa (UFV)Universidade Estadual Paulista (UNESP)Filippo, Paula Alessandra DiDuarte, Bárbara RibeiroAlbernaz, Antônio PeixotoFonseca, Leandro Abreu DaViana, Inácio Silva [UNESP]Quirino, Célia Raquel2023-07-29T11:14:55Z2023-07-29T11:14:55Z2022-09-09info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article-application/pdfhttp://dx.doi.org/10.1590/1809-6891v23e-72445ECiência Animal Brasileira. Universidade Federal de Goiás, v. 23, p. -, 2022.1518-27971809-6891http://hdl.handle.net/11449/24485910.1590/1809-6891v23e-72445ES1809-68912022000100219S1809-68912022000100219.pdfSciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengCiência Animal Brasileirainfo:eu-repo/semantics/openAccess2024-01-27T06:53:41Zoai:repositorio.unesp.br:11449/244859Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462024-01-27T06:53:41Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Effects of 48-hour feed deprivation on acute-phase response in horses |
title |
Effects of 48-hour feed deprivation on acute-phase response in horses |
spellingShingle |
Effects of 48-hour feed deprivation on acute-phase response in horses Filippo, Paula Alessandra Di Equine Feed restriction Inflammation Immune response Proteins Stress |
title_short |
Effects of 48-hour feed deprivation on acute-phase response in horses |
title_full |
Effects of 48-hour feed deprivation on acute-phase response in horses |
title_fullStr |
Effects of 48-hour feed deprivation on acute-phase response in horses |
title_full_unstemmed |
Effects of 48-hour feed deprivation on acute-phase response in horses |
title_sort |
Effects of 48-hour feed deprivation on acute-phase response in horses |
author |
Filippo, Paula Alessandra Di |
author_facet |
Filippo, Paula Alessandra Di Duarte, Bárbara Ribeiro Albernaz, Antônio Peixoto Fonseca, Leandro Abreu Da Viana, Inácio Silva [UNESP] Quirino, Célia Raquel |
author_role |
author |
author2 |
Duarte, Bárbara Ribeiro Albernaz, Antônio Peixoto Fonseca, Leandro Abreu Da Viana, Inácio Silva [UNESP] Quirino, Célia Raquel |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual do Norte Fluminense Darcy Ribeiro (UENF) Universidade Federal de Viçosa (UFV) Universidade Estadual Paulista (UNESP) |
dc.contributor.author.fl_str_mv |
Filippo, Paula Alessandra Di Duarte, Bárbara Ribeiro Albernaz, Antônio Peixoto Fonseca, Leandro Abreu Da Viana, Inácio Silva [UNESP] Quirino, Célia Raquel |
dc.subject.por.fl_str_mv |
Equine Feed restriction Inflammation Immune response Proteins Stress |
topic |
Equine Feed restriction Inflammation Immune response Proteins Stress |
description |
The objective of this study was to evaluate the effect of feed restriction on acute-phase response in horses. Twenty horses were deprived of food for 48 h and others 12 animals (control) had free access to water and hay. They were closely monitored and examined, and blood samples were taken at the beginning (0) of the study and 6, 12, 18, 24, 30, 36, 42 and 48 hours afterward. Data were submitted to two-way analysis of variance with repeated measures and statistical significance was P ≤ 0.05. The horses tolerated feed restriction without serious clinical complications. Feed restriction induced an increase in the acute-phase response by elevating serum concentrations of α2-macroglobulin (24-38 h), ceruloplasmin (36-48 h), α1-antitrypsin (30-48 h), α1-acid glycoprotein (42-48 h) and haptoglobin (42-48 h). Nutrient deprivation raised the levels of circulating cortisol, which acts on the innate immune system, which then induces the acute-phase response. In conclusion, food restriction is a physical stressor for horses, capable of inducing an acute-phase protein reaction, characterized by increased production of α2-macroglobulin, ceruloplasmin, α1- antitrypsin, α1-acid glycoprotein and haptoglobin. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-09-09 2023-07-29T11:14:55Z 2023-07-29T11:14:55Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/1809-6891v23e-72445E Ciência Animal Brasileira. Universidade Federal de Goiás, v. 23, p. -, 2022. 1518-2797 1809-6891 http://hdl.handle.net/11449/244859 10.1590/1809-6891v23e-72445E S1809-68912022000100219 S1809-68912022000100219.pdf |
url |
http://dx.doi.org/10.1590/1809-6891v23e-72445E http://hdl.handle.net/11449/244859 |
identifier_str_mv |
Ciência Animal Brasileira. Universidade Federal de Goiás, v. 23, p. -, 2022. 1518-2797 1809-6891 10.1590/1809-6891v23e-72445E S1809-68912022000100219 S1809-68912022000100219.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Ciência Animal Brasileira |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
- application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Goiás |
publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.source.none.fl_str_mv |
SciELO reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799965737951952896 |