Control of canine visceral leishmaniasis by euthanasia: estimated effect based on a survey and mathematical modeling
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/0102-311X00221418 http://hdl.handle.net/11449/197694 |
Resumo: | Visceral leishmaniasis is an emerging and neglected disease that is currently expanding to urban areas. The incidence of human disease is related to canine infection. Aracatuba and Birigui are municipalities (counties) in the state of Sao Paulo, Brazil, with 8-10% seroprevalence of canine infection and that employ control strategies targeting the canine reservoir, based on serological survey and culling of seropositive dogs. Using data from these control programs to parameterize mathematical models, this study assessed the efficacy of these activities. We estimated that current control is capable of reducing the incidence of canine visceral leishmaniasis (CVL) by approximately 20%. Assuming continuous control and three times the current serological survey activities in Aracatuba and Birigui, culling dogs with a positive CVL diagnosis would be effective for the control of canine infection. Although theoretically possible, in practice the control of CVL with the currently recommended strategies is insufficient, since it would require overcoming the difficulties in these activities, such as lack of material, human, and financial resources, besides associated ethical and legal issues. |
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Control of canine visceral leishmaniasis by euthanasia: estimated effect based on a survey and mathematical modelingLeishmaniaVisceral LeishmaniasisDog DiseasesDisease ReservoirsVisceral leishmaniasis is an emerging and neglected disease that is currently expanding to urban areas. The incidence of human disease is related to canine infection. Aracatuba and Birigui are municipalities (counties) in the state of Sao Paulo, Brazil, with 8-10% seroprevalence of canine infection and that employ control strategies targeting the canine reservoir, based on serological survey and culling of seropositive dogs. Using data from these control programs to parameterize mathematical models, this study assessed the efficacy of these activities. We estimated that current control is capable of reducing the incidence of canine visceral leishmaniasis (CVL) by approximately 20%. Assuming continuous control and three times the current serological survey activities in Aracatuba and Birigui, culling dogs with a positive CVL diagnosis would be effective for the control of canine infection. Although theoretically possible, in practice the control of CVL with the currently recommended strategies is insufficient, since it would require overcoming the difficulties in these activities, such as lack of material, human, and financial resources, besides associated ethical and legal issues.Univ Sao Paulo, Fac Saude Publ, Av Dr Arnaldo 715, BR-01246904 Sao Paulo, SP, BrazilFundacao Oswaldo Cruz, Programa Comp Cient, Rio De Janeiro, BrazilSuperintendencia Controle Endemias, Serv Reg 9, Aracatuba, BrazilUniv Estadual Paulista, Fac Med Vet Aracatuba, Aracatuba, BrazilAdolfo Lutz Inst, Nucleo Parasitoses Sistem, Sao Paulo, BrazilUniv Estadual Paulista, Fac Med Vet Aracatuba, Aracatuba, BrazilCadernos Saude PublicaUniversidade de São Paulo (USP)Fundacao Oswaldo CruzSuperintendencia Controle EndemiasUniversidade Estadual Paulista (Unesp)Adolfo Lutz InstCarneiro Castro Costa, Danielle NunesCodeco, Claudia TorresMoralejo Bermudi, Patricia MarquesColebrusco Rodas, Lilian AparecidaNunes, Caris Maroni [UNESP]Hiramoto, Roberto MitsuyoshiTolezano, Jose EduardoChiaravalloti Neto, Francisco2020-12-11T11:00:47Z2020-12-11T11:00:47Z2020-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article14application/pdfhttp://dx.doi.org/10.1590/0102-311X00221418Cadernos De Saude Publica. Rio De Janiero: Cadernos Saude Publica, v. 36, n. 2, 14 p., 2020.0102-311Xhttp://hdl.handle.net/11449/19769410.1590/0102-311X00221418S0102-311X2020000205008WOS:000518811200001S0102-311X2020000205008.pdfWeb of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPporCadernos De Saude Publicainfo:eu-repo/semantics/openAccess2023-10-24T06:07:53Zoai:repositorio.unesp.br:11449/197694Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-10-24T06:07:53Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Control of canine visceral leishmaniasis by euthanasia: estimated effect based on a survey and mathematical modeling |
title |
Control of canine visceral leishmaniasis by euthanasia: estimated effect based on a survey and mathematical modeling |
spellingShingle |
Control of canine visceral leishmaniasis by euthanasia: estimated effect based on a survey and mathematical modeling Carneiro Castro Costa, Danielle Nunes Leishmania Visceral Leishmaniasis Dog Diseases Disease Reservoirs |
title_short |
Control of canine visceral leishmaniasis by euthanasia: estimated effect based on a survey and mathematical modeling |
title_full |
Control of canine visceral leishmaniasis by euthanasia: estimated effect based on a survey and mathematical modeling |
title_fullStr |
Control of canine visceral leishmaniasis by euthanasia: estimated effect based on a survey and mathematical modeling |
title_full_unstemmed |
Control of canine visceral leishmaniasis by euthanasia: estimated effect based on a survey and mathematical modeling |
title_sort |
Control of canine visceral leishmaniasis by euthanasia: estimated effect based on a survey and mathematical modeling |
author |
Carneiro Castro Costa, Danielle Nunes |
author_facet |
Carneiro Castro Costa, Danielle Nunes Codeco, Claudia Torres Moralejo Bermudi, Patricia Marques Colebrusco Rodas, Lilian Aparecida Nunes, Caris Maroni [UNESP] Hiramoto, Roberto Mitsuyoshi Tolezano, Jose Eduardo Chiaravalloti Neto, Francisco |
author_role |
author |
author2 |
Codeco, Claudia Torres Moralejo Bermudi, Patricia Marques Colebrusco Rodas, Lilian Aparecida Nunes, Caris Maroni [UNESP] Hiramoto, Roberto Mitsuyoshi Tolezano, Jose Eduardo Chiaravalloti Neto, Francisco |
author2_role |
author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) Fundacao Oswaldo Cruz Superintendencia Controle Endemias Universidade Estadual Paulista (Unesp) Adolfo Lutz Inst |
dc.contributor.author.fl_str_mv |
Carneiro Castro Costa, Danielle Nunes Codeco, Claudia Torres Moralejo Bermudi, Patricia Marques Colebrusco Rodas, Lilian Aparecida Nunes, Caris Maroni [UNESP] Hiramoto, Roberto Mitsuyoshi Tolezano, Jose Eduardo Chiaravalloti Neto, Francisco |
dc.subject.por.fl_str_mv |
Leishmania Visceral Leishmaniasis Dog Diseases Disease Reservoirs |
topic |
Leishmania Visceral Leishmaniasis Dog Diseases Disease Reservoirs |
description |
Visceral leishmaniasis is an emerging and neglected disease that is currently expanding to urban areas. The incidence of human disease is related to canine infection. Aracatuba and Birigui are municipalities (counties) in the state of Sao Paulo, Brazil, with 8-10% seroprevalence of canine infection and that employ control strategies targeting the canine reservoir, based on serological survey and culling of seropositive dogs. Using data from these control programs to parameterize mathematical models, this study assessed the efficacy of these activities. We estimated that current control is capable of reducing the incidence of canine visceral leishmaniasis (CVL) by approximately 20%. Assuming continuous control and three times the current serological survey activities in Aracatuba and Birigui, culling dogs with a positive CVL diagnosis would be effective for the control of canine infection. Although theoretically possible, in practice the control of CVL with the currently recommended strategies is insufficient, since it would require overcoming the difficulties in these activities, such as lack of material, human, and financial resources, besides associated ethical and legal issues. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-11T11:00:47Z 2020-12-11T11:00:47Z 2020-01-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/0102-311X00221418 Cadernos De Saude Publica. Rio De Janiero: Cadernos Saude Publica, v. 36, n. 2, 14 p., 2020. 0102-311X http://hdl.handle.net/11449/197694 10.1590/0102-311X00221418 S0102-311X2020000205008 WOS:000518811200001 S0102-311X2020000205008.pdf |
url |
http://dx.doi.org/10.1590/0102-311X00221418 http://hdl.handle.net/11449/197694 |
identifier_str_mv |
Cadernos De Saude Publica. Rio De Janiero: Cadernos Saude Publica, v. 36, n. 2, 14 p., 2020. 0102-311X 10.1590/0102-311X00221418 S0102-311X2020000205008 WOS:000518811200001 S0102-311X2020000205008.pdf |
dc.language.iso.fl_str_mv |
por |
language |
por |
dc.relation.none.fl_str_mv |
Cadernos De Saude Publica |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
14 application/pdf |
dc.publisher.none.fl_str_mv |
Cadernos Saude Publica |
publisher.none.fl_str_mv |
Cadernos Saude Publica |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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