Pathological and molecular characterization of avian malaria in captive Magellanic penguins (Spheniscus magellanicus) in South America
Autor(a) principal: | |
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Data de Publicação: | 2019 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1007/s00436-018-6155-5 http://hdl.handle.net/11449/188389 |
Resumo: | Avian malaria is a mosquito-borne disease that affects multiple avian species and is caused by protozoans of the genus Plasmodium. An avian malaria infection caused by Plasmodium sp. in Magellanic penguins (Spheniscus magellanicus) with high mortality is described in a zoo in Southern Brazil. Clinically, three birds presented signs of inappetence, anorexia, pale mucosa, dyspnea, and opisthotonus, with death in a clinical course of 5–8 h. At the necropsy, all birds exhibited pale mucosa, marked splenomegaly and hepatomegaly, in addition to moderate leptomeningeal blood vessels ingurgitation in the brain. Microscopically, multiple exoerythrocytic meronts were observed in the cytoplasm of endothelial cells in the spleen, liver, heart, lungs, brain, kidneys, and pancreas. The spleen had a multifocal perivascular inflammatory infiltrate of lymphocytes, plasma cells, and macrophages, which also exhibited hemosiderosis and erythrophagocytosis. The liver had a multifocal periportal inflammatory infiltrate of lymphocytes, macrophages, and plasma cells, in addition to marked hemosiderosis in the hepatic sinusoids. Fragments of spleen, liver, brain, skeletal muscle, and lung were tested by the polymerase chain reaction technique for the detection of a fragment of the cytochrome B gene from haemosporidians, which resulted positive for Plasmodium spp. After sequencing, the samples were phylogenetically associated to Plasmodium sp. detected in Turdus albicollis (KU562808) in Brazil and matched to the lineage TURALB01 previously detected in T. albicollis. Avian malaria infections caused by Plasmodium sp. of lineage TURALB01 may occur in S. magellanicus with high mortality, and, thus, it is essential to detect and characterize the agent involved to obtain the differential diagnosis of the condition. |
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Pathological and molecular characterization of avian malaria in captive Magellanic penguins (Spheniscus magellanicus) in South AmericaCulicidaeHaemosporidian parasitesMorphologic analysesPhylogenetic analysesPlasmodium sppAvian malaria is a mosquito-borne disease that affects multiple avian species and is caused by protozoans of the genus Plasmodium. An avian malaria infection caused by Plasmodium sp. in Magellanic penguins (Spheniscus magellanicus) with high mortality is described in a zoo in Southern Brazil. Clinically, three birds presented signs of inappetence, anorexia, pale mucosa, dyspnea, and opisthotonus, with death in a clinical course of 5–8 h. At the necropsy, all birds exhibited pale mucosa, marked splenomegaly and hepatomegaly, in addition to moderate leptomeningeal blood vessels ingurgitation in the brain. Microscopically, multiple exoerythrocytic meronts were observed in the cytoplasm of endothelial cells in the spleen, liver, heart, lungs, brain, kidneys, and pancreas. The spleen had a multifocal perivascular inflammatory infiltrate of lymphocytes, plasma cells, and macrophages, which also exhibited hemosiderosis and erythrophagocytosis. The liver had a multifocal periportal inflammatory infiltrate of lymphocytes, macrophages, and plasma cells, in addition to marked hemosiderosis in the hepatic sinusoids. Fragments of spleen, liver, brain, skeletal muscle, and lung were tested by the polymerase chain reaction technique for the detection of a fragment of the cytochrome B gene from haemosporidians, which resulted positive for Plasmodium spp. After sequencing, the samples were phylogenetically associated to Plasmodium sp. detected in Turdus albicollis (KU562808) in Brazil and matched to the lineage TURALB01 previously detected in T. albicollis. Avian malaria infections caused by Plasmodium sp. of lineage TURALB01 may occur in S. magellanicus with high mortality, and, thus, it is essential to detect and characterize the agent involved to obtain the differential diagnosis of the condition.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Departamento de Patologia Clínica Veterinária Setor de Patologia Veterinária Faculdade de Veterinária Universidade Federal do Rio Grande do Sul (UFRGS), Av. Bento Gonçalves 9090, Prédio 42505Departamento de Patologia Veterinária Laboratório de Imunoparasitologia Faculdade de Ciências Agrárias e Veterinárias (FCAV) Universidade do Estado de São Paulo (UNESP), Via de Acesso Prof. Paulo Donato CastellaniGramadoZooDepartamento de Patologia Veterinária Laboratório de Imunoparasitologia Faculdade de Ciências Agrárias e Veterinárias (FCAV) Universidade do Estado de São Paulo (UNESP), Via de Acesso Prof. Paulo Donato CastellaniUniversidade Federal do Rio Grande do Sul (UFRGS)Universidade Estadual Paulista (Unesp)GramadoZooTaunde, Paula AugustoBianchi, Matheus ViezzerPerles, Lívia [UNESP]da Silva, Fernando SoaresGuim, Tainã NormantonStadler, Renan AlvesAndré, Marcos Rogério [UNESP]Driemeier, DavidPavarini, Saulo Petinatti2019-10-06T16:06:27Z2019-10-06T16:06:27Z2019-02-14info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article599-606http://dx.doi.org/10.1007/s00436-018-6155-5Parasitology Research, v. 118, n. 2, p. 599-606, 2019.1432-19550932-0113http://hdl.handle.net/11449/18838910.1007/s00436-018-6155-52-s2.0-85056864443Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengParasitology Researchinfo:eu-repo/semantics/openAccess2021-10-22T21:09:51Zoai:repositorio.unesp.br:11449/188389Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-22T21:09:51Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Pathological and molecular characterization of avian malaria in captive Magellanic penguins (Spheniscus magellanicus) in South America |
title |
Pathological and molecular characterization of avian malaria in captive Magellanic penguins (Spheniscus magellanicus) in South America |
spellingShingle |
Pathological and molecular characterization of avian malaria in captive Magellanic penguins (Spheniscus magellanicus) in South America Taunde, Paula Augusto Culicidae Haemosporidian parasites Morphologic analyses Phylogenetic analyses Plasmodium spp |
title_short |
Pathological and molecular characterization of avian malaria in captive Magellanic penguins (Spheniscus magellanicus) in South America |
title_full |
Pathological and molecular characterization of avian malaria in captive Magellanic penguins (Spheniscus magellanicus) in South America |
title_fullStr |
Pathological and molecular characterization of avian malaria in captive Magellanic penguins (Spheniscus magellanicus) in South America |
title_full_unstemmed |
Pathological and molecular characterization of avian malaria in captive Magellanic penguins (Spheniscus magellanicus) in South America |
title_sort |
Pathological and molecular characterization of avian malaria in captive Magellanic penguins (Spheniscus magellanicus) in South America |
author |
Taunde, Paula Augusto |
author_facet |
Taunde, Paula Augusto Bianchi, Matheus Viezzer Perles, Lívia [UNESP] da Silva, Fernando Soares Guim, Tainã Normanton Stadler, Renan Alves André, Marcos Rogério [UNESP] Driemeier, David Pavarini, Saulo Petinatti |
author_role |
author |
author2 |
Bianchi, Matheus Viezzer Perles, Lívia [UNESP] da Silva, Fernando Soares Guim, Tainã Normanton Stadler, Renan Alves André, Marcos Rogério [UNESP] Driemeier, David Pavarini, Saulo Petinatti |
author2_role |
author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal do Rio Grande do Sul (UFRGS) Universidade Estadual Paulista (Unesp) GramadoZoo |
dc.contributor.author.fl_str_mv |
Taunde, Paula Augusto Bianchi, Matheus Viezzer Perles, Lívia [UNESP] da Silva, Fernando Soares Guim, Tainã Normanton Stadler, Renan Alves André, Marcos Rogério [UNESP] Driemeier, David Pavarini, Saulo Petinatti |
dc.subject.por.fl_str_mv |
Culicidae Haemosporidian parasites Morphologic analyses Phylogenetic analyses Plasmodium spp |
topic |
Culicidae Haemosporidian parasites Morphologic analyses Phylogenetic analyses Plasmodium spp |
description |
Avian malaria is a mosquito-borne disease that affects multiple avian species and is caused by protozoans of the genus Plasmodium. An avian malaria infection caused by Plasmodium sp. in Magellanic penguins (Spheniscus magellanicus) with high mortality is described in a zoo in Southern Brazil. Clinically, three birds presented signs of inappetence, anorexia, pale mucosa, dyspnea, and opisthotonus, with death in a clinical course of 5–8 h. At the necropsy, all birds exhibited pale mucosa, marked splenomegaly and hepatomegaly, in addition to moderate leptomeningeal blood vessels ingurgitation in the brain. Microscopically, multiple exoerythrocytic meronts were observed in the cytoplasm of endothelial cells in the spleen, liver, heart, lungs, brain, kidneys, and pancreas. The spleen had a multifocal perivascular inflammatory infiltrate of lymphocytes, plasma cells, and macrophages, which also exhibited hemosiderosis and erythrophagocytosis. The liver had a multifocal periportal inflammatory infiltrate of lymphocytes, macrophages, and plasma cells, in addition to marked hemosiderosis in the hepatic sinusoids. Fragments of spleen, liver, brain, skeletal muscle, and lung were tested by the polymerase chain reaction technique for the detection of a fragment of the cytochrome B gene from haemosporidians, which resulted positive for Plasmodium spp. After sequencing, the samples were phylogenetically associated to Plasmodium sp. detected in Turdus albicollis (KU562808) in Brazil and matched to the lineage TURALB01 previously detected in T. albicollis. Avian malaria infections caused by Plasmodium sp. of lineage TURALB01 may occur in S. magellanicus with high mortality, and, thus, it is essential to detect and characterize the agent involved to obtain the differential diagnosis of the condition. |
publishDate |
2019 |
dc.date.none.fl_str_mv |
2019-10-06T16:06:27Z 2019-10-06T16:06:27Z 2019-02-14 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1007/s00436-018-6155-5 Parasitology Research, v. 118, n. 2, p. 599-606, 2019. 1432-1955 0932-0113 http://hdl.handle.net/11449/188389 10.1007/s00436-018-6155-5 2-s2.0-85056864443 |
url |
http://dx.doi.org/10.1007/s00436-018-6155-5 http://hdl.handle.net/11449/188389 |
identifier_str_mv |
Parasitology Research, v. 118, n. 2, p. 599-606, 2019. 1432-1955 0932-0113 10.1007/s00436-018-6155-5 2-s2.0-85056864443 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Parasitology Research |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
599-606 |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1797790022230867968 |