Influence of the Vehicle on the Tissue Reaction and Biomineralization of Fast Endodontic Cement

• Autor(a) principal: Sales, Luciana Solera [UNESP]
• Data de Publicação: 2021
• Outros Autores: Santos, Alailson Domingos dos [UNESP], Cosme-Silva, Leopoldo, Azevedo Queiroz, India Olinta de [UNESP], Martins, Christine Men [UNESP], Dal Fabbro, Renan [UNESP], Silos Moraes, Joao Carlos [UNESP], Angelo Cintra, Luciano Tavares [UNESP], Magalhaes Bertoz, Andre Pinheiro de [UNESP], Gomes Filho, Joao Eduardo [UNESP]
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Institucional da UNESP
• Texto Completo: http://dx.doi.org/10.1590/pboci.2021.053; http://hdl.handle.net/11449/210019
• topic: Endodontics; Biocompatible Materials; Biomineralization; Root Canal Therapy

Objective: To investigate the tissue response and the biomineralization ability of CER prepared with epoxy resin or water compared to Mineral Trioxide Aggregate (MTA). Material and Methods: Polyethylene tubes containing materials or empty tubes for control were inserted into the subcutaneous tissues of 30 rats. After 7, 15, 30, 60, and 90 days, the rats were killed and the tubes were removed for analysis using hematoxylin-eosin staining, von Kossa staining, and under polarized light. Inflammation was graded through a score system; the thickness of the fibrous capsule was classified as thin or thick; the biomineralization ability was recorded as present or absent. The results were statistically analyzed using the Kruskal-Wallis test (p<0.05). Results: Histologic analysis performed after 7 and 15 days for CER prepared with epoxy resin or water and for MTA showed moderate inflammation and a thick fibrous capsule (p>0.05). After 30, 60, and 90 days, mild inflammation, and a thin fibrous capsule were observed in all groups (p>0.05). Conclusion: All materials had structures positive for von Kossa and birefringent to polarized light. CER epoxy resin showed biocompatibility and biomineralization similar to CER water and MTA.