Highly divergent herpesviruses in threatened river dolphins from Brazil
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1038/s41598-021-04059-0 http://hdl.handle.net/11449/230188 |
Resumo: | River dolphins are a highly threatened polyphyletic group comprised of four odontocete families: Iniidae, Pontoporiidae, Lipotidae, and Platanistidae, the first two endemic to South America. To address the knowledge gap regarding infectious agents in this cetacean group, we surveyed the presence of herpesviruses by PCR in skin and/or blood samples of live-captured Amazon (Inia geoffrensis, n = 25) and Bolivian (Inia boliviensis, n = 22) river dolphins of the Amazon basin and in selected tissue samples of franciscanas (Pontoporia blainvillei, n = 27) stranded or bycaught in southeastern Brazil. Additionally, available franciscana tissue samples were examined by histopathology. Herpesvirus DNA was amplified in 13 Bolivian river dolphins (59.1%, 95% CI 38.5–79.6%) and 14 franciscanas (51.9%, 95% CI 33.0–70.7%). All Amazon river dolphins were herpesvirus-negative. Two different herpesviruses were found in Bolivian river dolphins: a previously known gammaherpesvirus detected in blood and/or skin samples of all positive individuals and a novel alphaherpesvirus in the skin of one animal. A new gammaherpesvirus was found in several franciscana samples—the first herpesvirus recorded in Pontoporiidae. Intranuclear inclusion bodies consistent with herpesvirus were observed in the lymph node of one franciscana. The high divergence among the obtained herpesviruses and those previously described can be explained by viral-host coevolution, and by the fact that these populations are fairly isolated. |
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Highly divergent herpesviruses in threatened river dolphins from BrazilRiver dolphins are a highly threatened polyphyletic group comprised of four odontocete families: Iniidae, Pontoporiidae, Lipotidae, and Platanistidae, the first two endemic to South America. To address the knowledge gap regarding infectious agents in this cetacean group, we surveyed the presence of herpesviruses by PCR in skin and/or blood samples of live-captured Amazon (Inia geoffrensis, n = 25) and Bolivian (Inia boliviensis, n = 22) river dolphins of the Amazon basin and in selected tissue samples of franciscanas (Pontoporia blainvillei, n = 27) stranded or bycaught in southeastern Brazil. Additionally, available franciscana tissue samples were examined by histopathology. Herpesvirus DNA was amplified in 13 Bolivian river dolphins (59.1%, 95% CI 38.5–79.6%) and 14 franciscanas (51.9%, 95% CI 33.0–70.7%). All Amazon river dolphins were herpesvirus-negative. Two different herpesviruses were found in Bolivian river dolphins: a previously known gammaherpesvirus detected in blood and/or skin samples of all positive individuals and a novel alphaherpesvirus in the skin of one animal. A new gammaherpesvirus was found in several franciscana samples—the first herpesvirus recorded in Pontoporiidae. Intranuclear inclusion bodies consistent with herpesvirus were observed in the lymph node of one franciscana. The high divergence among the obtained herpesviruses and those previously described can be explained by viral-host coevolution, and by the fact that these populations are fairly isolated.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Laboratory of Wildlife Comparative Pathology Department of Pathology School of Veterinary Medicine and Animal Sciences University of São Paulo, SPInstituto Nacional de Pesquisas da Amazônia, AMInstituto de Saúde e Biotecnologia Universidade Federal do Amazonas, AMAssociação de Pesquisa e Preservação de Ecossistemas Aquáticos, CEInstituto de Desenvolvimento Sustentável Mamirauá, AMInstituto de Biociências Universidade Estadual Paulista–UNESP, Campus do Litoral Paulista, SPInstituto Biopesca, SPNorwegian Veterinary Institute, Arboretveien 57Veterinary Department School of Biomedical and Health Sciences Universidad Europea de Madrid, C/Tajo S/N, Villaviciosa de OdónInstituto de Biociências Universidade Estadual Paulista–UNESP, Campus do Litoral Paulista, SPFAPESP: 2016/20956-0FAPESP: 2018/25069-7CNPq: 304999-18Universidade de São Paulo (USP)Instituto Nacional de Pesquisas da AmazôniaUniversidade Federal do AmazonasAssociação de Pesquisa e Preservação de Ecossistemas AquáticosInstituto de Desenvolvimento Sustentável MamirauáUniversidade Estadual Paulista (UNESP)Instituto BiopescaNorwegian Veterinary InstituteUniversidad Europea de MadridExposto Novoselecki, HelenaCatão-Dias, José LuizEwbank, Ana CarolinaNavas-Suárez, Pedro EnriqueDuarte-Benvenuto, AriciaLial, Henrique ChristinoCosta Silva, SamiraSánchez-Sarmiento, Angélica MaríaGravena, Waleskada Silva, Vera Maria FerreiraCarvalho, Vitor L.Marmontel, MiriamBertozzi, Carolina P. [UNESP]Lanes Ribeiro, Vanessa [UNESP]del Rio do Valle, RodrigoMarigo, Julianadas Neves, Carlos G.Esperón, FernandoSacristán, Carlos2022-04-29T08:38:19Z2022-04-29T08:38:19Z2021-12-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://dx.doi.org/10.1038/s41598-021-04059-0Scientific Reports, v. 11, n. 1, 2021.2045-2322http://hdl.handle.net/11449/23018810.1038/s41598-021-04059-02-s2.0-85122491431Scopusreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengScientific Reportsinfo:eu-repo/semantics/openAccess2022-04-29T08:38:19Zoai:repositorio.unesp.br:11449/230188Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-04-29T08:38:19Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Highly divergent herpesviruses in threatened river dolphins from Brazil |
title |
Highly divergent herpesviruses in threatened river dolphins from Brazil |
spellingShingle |
Highly divergent herpesviruses in threatened river dolphins from Brazil Exposto Novoselecki, Helena |
title_short |
Highly divergent herpesviruses in threatened river dolphins from Brazil |
title_full |
Highly divergent herpesviruses in threatened river dolphins from Brazil |
title_fullStr |
Highly divergent herpesviruses in threatened river dolphins from Brazil |
title_full_unstemmed |
Highly divergent herpesviruses in threatened river dolphins from Brazil |
title_sort |
Highly divergent herpesviruses in threatened river dolphins from Brazil |
author |
Exposto Novoselecki, Helena |
author_facet |
Exposto Novoselecki, Helena Catão-Dias, José Luiz Ewbank, Ana Carolina Navas-Suárez, Pedro Enrique Duarte-Benvenuto, Aricia Lial, Henrique Christino Costa Silva, Samira Sánchez-Sarmiento, Angélica María Gravena, Waleska da Silva, Vera Maria Ferreira Carvalho, Vitor L. Marmontel, Miriam Bertozzi, Carolina P. [UNESP] Lanes Ribeiro, Vanessa [UNESP] del Rio do Valle, Rodrigo Marigo, Juliana das Neves, Carlos G. Esperón, Fernando Sacristán, Carlos |
author_role |
author |
author2 |
Catão-Dias, José Luiz Ewbank, Ana Carolina Navas-Suárez, Pedro Enrique Duarte-Benvenuto, Aricia Lial, Henrique Christino Costa Silva, Samira Sánchez-Sarmiento, Angélica María Gravena, Waleska da Silva, Vera Maria Ferreira Carvalho, Vitor L. Marmontel, Miriam Bertozzi, Carolina P. [UNESP] Lanes Ribeiro, Vanessa [UNESP] del Rio do Valle, Rodrigo Marigo, Juliana das Neves, Carlos G. Esperón, Fernando Sacristán, Carlos |
author2_role |
author author author author author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) Instituto Nacional de Pesquisas da Amazônia Universidade Federal do Amazonas Associação de Pesquisa e Preservação de Ecossistemas Aquáticos Instituto de Desenvolvimento Sustentável Mamirauá Universidade Estadual Paulista (UNESP) Instituto Biopesca Norwegian Veterinary Institute Universidad Europea de Madrid |
dc.contributor.author.fl_str_mv |
Exposto Novoselecki, Helena Catão-Dias, José Luiz Ewbank, Ana Carolina Navas-Suárez, Pedro Enrique Duarte-Benvenuto, Aricia Lial, Henrique Christino Costa Silva, Samira Sánchez-Sarmiento, Angélica María Gravena, Waleska da Silva, Vera Maria Ferreira Carvalho, Vitor L. Marmontel, Miriam Bertozzi, Carolina P. [UNESP] Lanes Ribeiro, Vanessa [UNESP] del Rio do Valle, Rodrigo Marigo, Juliana das Neves, Carlos G. Esperón, Fernando Sacristán, Carlos |
description |
River dolphins are a highly threatened polyphyletic group comprised of four odontocete families: Iniidae, Pontoporiidae, Lipotidae, and Platanistidae, the first two endemic to South America. To address the knowledge gap regarding infectious agents in this cetacean group, we surveyed the presence of herpesviruses by PCR in skin and/or blood samples of live-captured Amazon (Inia geoffrensis, n = 25) and Bolivian (Inia boliviensis, n = 22) river dolphins of the Amazon basin and in selected tissue samples of franciscanas (Pontoporia blainvillei, n = 27) stranded or bycaught in southeastern Brazil. Additionally, available franciscana tissue samples were examined by histopathology. Herpesvirus DNA was amplified in 13 Bolivian river dolphins (59.1%, 95% CI 38.5–79.6%) and 14 franciscanas (51.9%, 95% CI 33.0–70.7%). All Amazon river dolphins were herpesvirus-negative. Two different herpesviruses were found in Bolivian river dolphins: a previously known gammaherpesvirus detected in blood and/or skin samples of all positive individuals and a novel alphaherpesvirus in the skin of one animal. A new gammaherpesvirus was found in several franciscana samples—the first herpesvirus recorded in Pontoporiidae. Intranuclear inclusion bodies consistent with herpesvirus were observed in the lymph node of one franciscana. The high divergence among the obtained herpesviruses and those previously described can be explained by viral-host coevolution, and by the fact that these populations are fairly isolated. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-12-01 2022-04-29T08:38:19Z 2022-04-29T08:38:19Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1038/s41598-021-04059-0 Scientific Reports, v. 11, n. 1, 2021. 2045-2322 http://hdl.handle.net/11449/230188 10.1038/s41598-021-04059-0 2-s2.0-85122491431 |
url |
http://dx.doi.org/10.1038/s41598-021-04059-0 http://hdl.handle.net/11449/230188 |
identifier_str_mv |
Scientific Reports, v. 11, n. 1, 2021. 2045-2322 10.1038/s41598-021-04059-0 2-s2.0-85122491431 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
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Scientific Reports |
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info:eu-repo/semantics/openAccess |
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openAccess |
dc.source.none.fl_str_mv |
Scopus reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
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UNESP |
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UNESP |
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Repositório Institucional da UNESP |
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Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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