Histological and radiological changes in cranial bone in the presence of bone wax
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2011 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Institucional da UNESP |
| Texto Completo: | http://dx.doi.org/10.1590/S0102-86502011000400005 http://hdl.handle.net/11449/14656 |
Resumo: | Purpose: To quantify the amount of bone formation in the calvarial region of Wistar rats after craniotomy using bone wax as a haemostatic agent. Methods: Surgery to produce bilateral, symmetric, full-thickness cranial defects (area: 18 mm(2)) was performed in eight animals. The right side of the cranium remained open and the edges of the left side osseous defect was covered with bone wax. Calvaria were imaged immediately after surgery and 12 weeks postoperatively by computerized tomography. The areas of the bone defects were measured in three-dimensional images using Magics 13.0 (Materialise-Belgic, software CAD). Results: The average amount of bone formation on the left and right side respectively was 4.85 mm(2) and 8.16 mm(2). Statistically significant differences between the amount of bone formation on the left and right sides were seen. Conclusion: Bone wax significantly diminishes the rate of bone formation in calvarial defects in a rat model. |
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Histological and radiological changes in cranial bone in the presence of bone waxAlterações histológicas e radiológicas no osso craniano na presença de cera de ossoWaxesSkullHemostaticsOsteogenesisRatsPurpose: To quantify the amount of bone formation in the calvarial region of Wistar rats after craniotomy using bone wax as a haemostatic agent. Methods: Surgery to produce bilateral, symmetric, full-thickness cranial defects (area: 18 mm(2)) was performed in eight animals. The right side of the cranium remained open and the edges of the left side osseous defect was covered with bone wax. Calvaria were imaged immediately after surgery and 12 weeks postoperatively by computerized tomography. The areas of the bone defects were measured in three-dimensional images using Magics 13.0 (Materialise-Belgic, software CAD). Results: The average amount of bone formation on the left and right side respectively was 4.85 mm(2) and 8.16 mm(2). Statistically significant differences between the amount of bone formation on the left and right sides were seen. Conclusion: Bone wax significantly diminishes the rate of bone formation in calvarial defects in a rat model.OBJETIVO: Quantificar a formação óssea da região da calvaria de ratos Wistar submetidos à craniotomia com a utilização de cera de osso como agente hemostático. MÉTODOS: Cirurgia para realizar um defeito ósseo craniano bilateral, simétrico (área: 18 mm2) e com espessura total foi realizado em oito animais. O lado direito do crânio permaneceu aberto e as extremidades do defeito ósseo do lado esquerdo foram recobertas com cera de osso. O crânio foi submetido à avaliação radiológica imediatamente após a cirurgia e 12 semanas após a cirurgia com a utilização de tomografia computadorizada. As áreas dos defeitos ósseos foram medidas através de imagens tridimensionais e utilizando o programa de computador Magics 13.0 (Materialise-Belgic, software CAD). RESULTADOS: A quantidade média de formação óssea no lado esquerdo e direito foi respectivamente de 4.85 mm2 e 8.16 mm2. Diferença estatisticamente significante foi observada entre o lado direito e esquerdo. CONCLUSÕES: A cera de osso diminuiu significativamente a formação óssea nos defeitos ósseos em modelo animal.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)CEPIDUniv São Paulo, Dept Genet & Evolut Biol, Inst Biosci, São Paulo, BrazilInst Craniofacial & Plast Surg, Campinas, SP, BrazilCtr Tecnol Informação Renato Arsher, Campinas, SP, BrazilState Univ São Paulo UNESP, Botucatu, SP, BrazilUniv São Paulo, Div Plast Surg, Dept Surg, BR-09500900 São Paulo, BrazilState Univ São Paulo UNESP, Botucatu, SP, BrazilActa Cirúrgica BrasileiraUniversidade de São Paulo (USP)Inst Craniofacial & Plast SurgCtr Tecnol Informação Renato ArsherUniversidade Estadual Paulista (Unesp)Raposo-Amaral, Cassio EduardoAlbino de Almeida, Ana BeatrizPaschoal, GustavoBueno, Daniela FrancoVulcano, Luiz Carlos [UNESP]Passos-Bueno, Maria RitaAlonso, Nivaldo2013-09-30T18:28:52Z2014-05-20T13:42:10Z2013-09-30T18:28:52Z2014-05-20T13:42:10Z2011-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article274-278application/pdfhttp://dx.doi.org/10.1590/S0102-86502011000400005Acta Cirúrgica Brasileira. São Paulo: Acta Cirúrgica Brasileira, v. 26, n. 4, p. 274-278, 2011.0102-8650http://hdl.handle.net/11449/14656S0102-86502011000400005WOS:000293408300005S0102-86502011000400005-en.pdf4065105014625753Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengActa Cirúrgica Brasileira0.9330,395info:eu-repo/semantics/openAccess2023-10-08T06:01:43Zoai:repositorio.unesp.br:11449/14656Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-10-08T06:01:43Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
| dc.title.none.fl_str_mv |
Histological and radiological changes in cranial bone in the presence of bone wax Alterações histológicas e radiológicas no osso craniano na presença de cera de osso |
| title |
Histological and radiological changes in cranial bone in the presence of bone wax |
| spellingShingle |
Histological and radiological changes in cranial bone in the presence of bone wax Raposo-Amaral, Cassio Eduardo Waxes Skull Hemostatics Osteogenesis Rats |
| title_short |
Histological and radiological changes in cranial bone in the presence of bone wax |
| title_full |
Histological and radiological changes in cranial bone in the presence of bone wax |
| title_fullStr |
Histological and radiological changes in cranial bone in the presence of bone wax |
| title_full_unstemmed |
Histological and radiological changes in cranial bone in the presence of bone wax |
| title_sort |
Histological and radiological changes in cranial bone in the presence of bone wax |
| author |
Raposo-Amaral, Cassio Eduardo |
| author_facet |
Raposo-Amaral, Cassio Eduardo Albino de Almeida, Ana Beatriz Paschoal, Gustavo Bueno, Daniela Franco Vulcano, Luiz Carlos [UNESP] Passos-Bueno, Maria Rita Alonso, Nivaldo |
| author_role |
author |
| author2 |
Albino de Almeida, Ana Beatriz Paschoal, Gustavo Bueno, Daniela Franco Vulcano, Luiz Carlos [UNESP] Passos-Bueno, Maria Rita Alonso, Nivaldo |
| author2_role |
author author author author author author |
| dc.contributor.none.fl_str_mv |
Universidade de São Paulo (USP) Inst Craniofacial & Plast Surg Ctr Tecnol Informação Renato Arsher Universidade Estadual Paulista (Unesp) |
| dc.contributor.author.fl_str_mv |
Raposo-Amaral, Cassio Eduardo Albino de Almeida, Ana Beatriz Paschoal, Gustavo Bueno, Daniela Franco Vulcano, Luiz Carlos [UNESP] Passos-Bueno, Maria Rita Alonso, Nivaldo |
| dc.subject.por.fl_str_mv |
Waxes Skull Hemostatics Osteogenesis Rats |
| topic |
Waxes Skull Hemostatics Osteogenesis Rats |
| description |
Purpose: To quantify the amount of bone formation in the calvarial region of Wistar rats after craniotomy using bone wax as a haemostatic agent. Methods: Surgery to produce bilateral, symmetric, full-thickness cranial defects (area: 18 mm(2)) was performed in eight animals. The right side of the cranium remained open and the edges of the left side osseous defect was covered with bone wax. Calvaria were imaged immediately after surgery and 12 weeks postoperatively by computerized tomography. The areas of the bone defects were measured in three-dimensional images using Magics 13.0 (Materialise-Belgic, software CAD). Results: The average amount of bone formation on the left and right side respectively was 4.85 mm(2) and 8.16 mm(2). Statistically significant differences between the amount of bone formation on the left and right sides were seen. Conclusion: Bone wax significantly diminishes the rate of bone formation in calvarial defects in a rat model. |
| publishDate |
2011 |
| dc.date.none.fl_str_mv |
2011-07-01 2013-09-30T18:28:52Z 2013-09-30T18:28:52Z 2014-05-20T13:42:10Z 2014-05-20T13:42:10Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/S0102-86502011000400005 Acta Cirúrgica Brasileira. São Paulo: Acta Cirúrgica Brasileira, v. 26, n. 4, p. 274-278, 2011. 0102-8650 http://hdl.handle.net/11449/14656 S0102-86502011000400005 WOS:000293408300005 S0102-86502011000400005-en.pdf 4065105014625753 |
| url |
http://dx.doi.org/10.1590/S0102-86502011000400005 http://hdl.handle.net/11449/14656 |
| identifier_str_mv |
Acta Cirúrgica Brasileira. São Paulo: Acta Cirúrgica Brasileira, v. 26, n. 4, p. 274-278, 2011. 0102-8650 S0102-86502011000400005 WOS:000293408300005 S0102-86502011000400005-en.pdf 4065105014625753 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
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Acta Cirúrgica Brasileira 0.933 0,395 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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274-278 application/pdf |
| dc.publisher.none.fl_str_mv |
Acta Cirúrgica Brasileira |
| publisher.none.fl_str_mv |
Acta Cirúrgica Brasileira |
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Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
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Universidade Estadual Paulista (UNESP) |
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UNESP |
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UNESP |
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Repositório Institucional da UNESP |
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Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
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