Spatial serosurvey of anti-Toxoplasma gondii antibodies in individuals with animal hoarding disorder and their dogs in Southern Brazil
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1371/journal.pone.0233305 http://hdl.handle.net/11449/196936 |
Resumo: | Despite vulnerability and unsanitary conditions of animal hoarding may predispose environmental contamination and spread of vectors and pathogens, no study to date has focused on their impact on public health and zoonotic diseases. Accordingly, this study aimed to assess the seroprevalence of anti-Toxoplasma gondii antibodies and associated factors in individuals with animal hoarding disorder (AHD) and their dogs in Curitiba, Southern Brazil. Blood samples were obtained from 264 dogs (21 households) and 19 individuals with AHD (11 households). Their blood was tested by indirect fluorescent antibody test (IFAT). Overall, anti-Toxoplasma gondii seropositivity was found in 21/264 dogs (7.95%; 95% CI: 4.69-11.22) with titers ranging from 16 to 4096, and in 7/19 individuals with AHD (36.84%; CI: 15.15-58.53) with titers ranging from 16 to 64. Serological analysis for anti-T. gondii antibodies were considered positive in at least one individual or dog in 9/11 (81.82%; 95% CI: 59.03-100.00) cases that were thoroughly assessed. Surprisingly, the seropositivity of individuals with AHD and their dogs was among the lowest reportedly observed in human and dog populations of Brazil. There was no significant association between positive owners and positive dogs or the presence of cats in the household. Regard epidemiological variables, a significant association was found between dog's seropositivity and the type of dog food. To the authors' knowledge, the present study represents the first investigation of T. gondii seroprevalence in individuals with hoarding disorder and their dogs. In conclusion, despite low sanitary conditions, anti-Toxoplasma gondii antibodies frequency in individuals with AHD and their dogs are lower than the general population likely due to low protozoan load in such isolated households. |
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Spatial serosurvey of anti-Toxoplasma gondii antibodies in individuals with animal hoarding disorder and their dogs in Southern BrazilDespite vulnerability and unsanitary conditions of animal hoarding may predispose environmental contamination and spread of vectors and pathogens, no study to date has focused on their impact on public health and zoonotic diseases. Accordingly, this study aimed to assess the seroprevalence of anti-Toxoplasma gondii antibodies and associated factors in individuals with animal hoarding disorder (AHD) and their dogs in Curitiba, Southern Brazil. Blood samples were obtained from 264 dogs (21 households) and 19 individuals with AHD (11 households). Their blood was tested by indirect fluorescent antibody test (IFAT). Overall, anti-Toxoplasma gondii seropositivity was found in 21/264 dogs (7.95%; 95% CI: 4.69-11.22) with titers ranging from 16 to 4096, and in 7/19 individuals with AHD (36.84%; CI: 15.15-58.53) with titers ranging from 16 to 64. Serological analysis for anti-T. gondii antibodies were considered positive in at least one individual or dog in 9/11 (81.82%; 95% CI: 59.03-100.00) cases that were thoroughly assessed. Surprisingly, the seropositivity of individuals with AHD and their dogs was among the lowest reportedly observed in human and dog populations of Brazil. There was no significant association between positive owners and positive dogs or the presence of cats in the household. Regard epidemiological variables, a significant association was found between dog's seropositivity and the type of dog food. To the authors' knowledge, the present study represents the first investigation of T. gondii seroprevalence in individuals with hoarding disorder and their dogs. In conclusion, despite low sanitary conditions, anti-Toxoplasma gondii antibodies frequency in individuals with AHD and their dogs are lower than the general population likely due to low protozoan load in such isolated households.Univ Fed Parana, Dept Vet Med, Curitiba, Parana, BrazilUniv Fed Bahia, Inst Collect Hlth, Salvador, BA, BrazilUniv Estadual Ponta Grossa, Dept Nursing & Publ Hlth, Ponta Grossa, Parana, BrazilAAC&T Res Consulting, Curitiba, Parana, BrazilSao Paulo State Univ, Sch Vet Med & Anim Sci, Dept Vet Hyg & Publ Hlth, Botucatu, SP, BrazilPurdue Univ, Coll Vet Med, Dept Comparat Pathobiol, W Lafayette, IN 47907 USAUniv Fed Parana, Dept Collect Hlth, Curitiba, Parana, BrazilSecretary Environm, Curitiba City Hall, Curitiba, Parana, BrazilSao Paulo State Univ, Sch Vet Med & Anim Sci, Dept Vet Hyg & Publ Hlth, Botucatu, SP, BrazilPublic Library ScienceUniv Fed ParanaUniversidade Federal da Bahia (UFBA)Universidade Estadual de Ponta Grossa (UEPG)AAC&T Res ConsultingUniversidade Estadual Paulista (Unesp)Purdue UnivSecretary EnvironmCunha, Graziela Ribeiro daPellizzaro, MaysaMartins, Camila MarinelliRocha, Suzana MariaYamakawa, Ana Carolina [UNESP]Silva, Evelyn Cristine da [UNESP]Santos, Andrea Pires dosMorikawa, Vivien MidoriLangoni, Helio [UNESP]Biondo, Alexander Welker2020-12-10T20:00:54Z2020-12-10T20:00:54Z2020-05-15info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article12http://dx.doi.org/10.1371/journal.pone.0233305Plos One. San Francisco: Public Library Science, v. 15, n. 5, 12 p., 2020.1932-6203http://hdl.handle.net/11449/19693610.1371/journal.pone.0233305WOS:000537496000062Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengPlos Oneinfo:eu-repo/semantics/openAccess2021-10-23T10:11:18Zoai:repositorio.unesp.br:11449/196936Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462021-10-23T10:11:18Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Spatial serosurvey of anti-Toxoplasma gondii antibodies in individuals with animal hoarding disorder and their dogs in Southern Brazil |
title |
Spatial serosurvey of anti-Toxoplasma gondii antibodies in individuals with animal hoarding disorder and their dogs in Southern Brazil |
spellingShingle |
Spatial serosurvey of anti-Toxoplasma gondii antibodies in individuals with animal hoarding disorder and their dogs in Southern Brazil Cunha, Graziela Ribeiro da |
title_short |
Spatial serosurvey of anti-Toxoplasma gondii antibodies in individuals with animal hoarding disorder and their dogs in Southern Brazil |
title_full |
Spatial serosurvey of anti-Toxoplasma gondii antibodies in individuals with animal hoarding disorder and their dogs in Southern Brazil |
title_fullStr |
Spatial serosurvey of anti-Toxoplasma gondii antibodies in individuals with animal hoarding disorder and their dogs in Southern Brazil |
title_full_unstemmed |
Spatial serosurvey of anti-Toxoplasma gondii antibodies in individuals with animal hoarding disorder and their dogs in Southern Brazil |
title_sort |
Spatial serosurvey of anti-Toxoplasma gondii antibodies in individuals with animal hoarding disorder and their dogs in Southern Brazil |
author |
Cunha, Graziela Ribeiro da |
author_facet |
Cunha, Graziela Ribeiro da Pellizzaro, Maysa Martins, Camila Marinelli Rocha, Suzana Maria Yamakawa, Ana Carolina [UNESP] Silva, Evelyn Cristine da [UNESP] Santos, Andrea Pires dos Morikawa, Vivien Midori Langoni, Helio [UNESP] Biondo, Alexander Welker |
author_role |
author |
author2 |
Pellizzaro, Maysa Martins, Camila Marinelli Rocha, Suzana Maria Yamakawa, Ana Carolina [UNESP] Silva, Evelyn Cristine da [UNESP] Santos, Andrea Pires dos Morikawa, Vivien Midori Langoni, Helio [UNESP] Biondo, Alexander Welker |
author2_role |
author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Univ Fed Parana Universidade Federal da Bahia (UFBA) Universidade Estadual de Ponta Grossa (UEPG) AAC&T Res Consulting Universidade Estadual Paulista (Unesp) Purdue Univ Secretary Environm |
dc.contributor.author.fl_str_mv |
Cunha, Graziela Ribeiro da Pellizzaro, Maysa Martins, Camila Marinelli Rocha, Suzana Maria Yamakawa, Ana Carolina [UNESP] Silva, Evelyn Cristine da [UNESP] Santos, Andrea Pires dos Morikawa, Vivien Midori Langoni, Helio [UNESP] Biondo, Alexander Welker |
description |
Despite vulnerability and unsanitary conditions of animal hoarding may predispose environmental contamination and spread of vectors and pathogens, no study to date has focused on their impact on public health and zoonotic diseases. Accordingly, this study aimed to assess the seroprevalence of anti-Toxoplasma gondii antibodies and associated factors in individuals with animal hoarding disorder (AHD) and their dogs in Curitiba, Southern Brazil. Blood samples were obtained from 264 dogs (21 households) and 19 individuals with AHD (11 households). Their blood was tested by indirect fluorescent antibody test (IFAT). Overall, anti-Toxoplasma gondii seropositivity was found in 21/264 dogs (7.95%; 95% CI: 4.69-11.22) with titers ranging from 16 to 4096, and in 7/19 individuals with AHD (36.84%; CI: 15.15-58.53) with titers ranging from 16 to 64. Serological analysis for anti-T. gondii antibodies were considered positive in at least one individual or dog in 9/11 (81.82%; 95% CI: 59.03-100.00) cases that were thoroughly assessed. Surprisingly, the seropositivity of individuals with AHD and their dogs was among the lowest reportedly observed in human and dog populations of Brazil. There was no significant association between positive owners and positive dogs or the presence of cats in the household. Regard epidemiological variables, a significant association was found between dog's seropositivity and the type of dog food. To the authors' knowledge, the present study represents the first investigation of T. gondii seroprevalence in individuals with hoarding disorder and their dogs. In conclusion, despite low sanitary conditions, anti-Toxoplasma gondii antibodies frequency in individuals with AHD and their dogs are lower than the general population likely due to low protozoan load in such isolated households. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-12-10T20:00:54Z 2020-12-10T20:00:54Z 2020-05-15 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1371/journal.pone.0233305 Plos One. San Francisco: Public Library Science, v. 15, n. 5, 12 p., 2020. 1932-6203 http://hdl.handle.net/11449/196936 10.1371/journal.pone.0233305 WOS:000537496000062 |
url |
http://dx.doi.org/10.1371/journal.pone.0233305 http://hdl.handle.net/11449/196936 |
identifier_str_mv |
Plos One. San Francisco: Public Library Science, v. 15, n. 5, 12 p., 2020. 1932-6203 10.1371/journal.pone.0233305 WOS:000537496000062 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
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Plos One |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
12 |
dc.publisher.none.fl_str_mv |
Public Library Science |
publisher.none.fl_str_mv |
Public Library Science |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
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Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
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UNESP |
reponame_str |
Repositório Institucional da UNESP |
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Repositório Institucional da UNESP |
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Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
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