Closure of defects in a geometric figure pattern associated with tumescent anesthesia with lidocaine in rabbits (Oryctolagus cuniculus)
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.1590/1809-6891v22e-7072e-70728 http://hdl.handle.net/11449/236927 |
Resumo: | The use of tumescent anesthesia with lidocaine can provide better intra- and postoperative analgesia that would benefit extensive reconstructive surgery. However, lidocaine can interfere with the healing process. Therefore, this study aimed to assess the local interference of the healing of induced and closed skin defects in a geometric pattern associated with the use of tumescent anesthesia with lidocaine in rabbits. Furthermore, we assessed its influence on cardiorespiratory parameters and postoperative analgesia. This study included 27 rabbits divided into three groups: GC (without the use of tumescence), GS (use of tumescence with 0.9% NaCl solution), and GL (use of tumescent anesthesia with lidocaine). There was no statistically significant intergroup difference in any stage of the wound healing process on macroscopic evaluations, in the angiogenesis process, or in the process of collagenization and fibroblast deposition. There were significant differences in heart rate (lower in GL), respiratory rate (higher in GC), mean arterial pressure (higher in GL), and expired concentration of isoflurane (lower in GL). There was no significant intergroup difference in the von Frey filament test or the visual analog scale score used to evaluate postoperative analgesia. We concluded that tumescent anesthesia with lidocaine does not impair postoperative tissue repair. Its use features benefits such as reducing the volume of inhaled anesthetic, maintaining the anesthesia plan, stable heart and respiratory rates, and lower hypotension during the surgical procedure. |
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Closure of defects in a geometric figure pattern associated with tumescent anesthesia with lidocaine in rabbits (Oryctolagus cuniculus)Local anestheticPainReconstructive surgeryTissue repairThe use of tumescent anesthesia with lidocaine can provide better intra- and postoperative analgesia that would benefit extensive reconstructive surgery. However, lidocaine can interfere with the healing process. Therefore, this study aimed to assess the local interference of the healing of induced and closed skin defects in a geometric pattern associated with the use of tumescent anesthesia with lidocaine in rabbits. Furthermore, we assessed its influence on cardiorespiratory parameters and postoperative analgesia. This study included 27 rabbits divided into three groups: GC (without the use of tumescence), GS (use of tumescence with 0.9% NaCl solution), and GL (use of tumescent anesthesia with lidocaine). There was no statistically significant intergroup difference in any stage of the wound healing process on macroscopic evaluations, in the angiogenesis process, or in the process of collagenization and fibroblast deposition. There were significant differences in heart rate (lower in GL), respiratory rate (higher in GC), mean arterial pressure (higher in GL), and expired concentration of isoflurane (lower in GL). There was no significant intergroup difference in the von Frey filament test or the visual analog scale score used to evaluate postoperative analgesia. We concluded that tumescent anesthesia with lidocaine does not impair postoperative tissue repair. Its use features benefits such as reducing the volume of inhaled anesthetic, maintaining the anesthesia plan, stable heart and respiratory rates, and lower hypotension during the surgical procedure.FACEPEConselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Universidade Estadual Paulista (UNESP)Universidade do Porto (ICBAS-UP)Universidade de NatñoUniversidade Estadual Paulista (UNESP)FACEPE: APQ-0202-5.05/17CNPq: 304804/2018-5Universidade Federal de GoiásUniversidade Estadual Paulista (UNESP)Universidade do Porto (ICBAS-UP)Universidade de NatñoSerafim, Eduardo Luís [UNESP]Pazzini, Josiane Morais [UNESP]Rocha, Michelle do Carmo Pereira [UNESP]Linhares, Laís Calazans Menescal [UNESP]Nardi, Andrigo Barboza de [UNESP]Gartner, Maria de Fátima MoutinhoAmorim, IrinaRema, AlexandraFaria, FátimaUscategui, Ricardo Andres Ramirez [UNESP]Almeida, Vivian Tavares De [UNESP]Calpaa, Carlos AlfredoCalazans, Sabrina Gouveia [UNESP]2022-10-10T13:56:15Z2022-10-10T13:56:15Z2022-04-06info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article-application/pdfhttp://dx.doi.org/10.1590/1809-6891v22e-7072e-70728Ciência Animal Brasileira. Universidade Federal de Goiás, v. 23, p. -, 2022.1518-27971809-6891http://hdl.handle.net/11449/23692710.1590/1809-6891v22e-7072e-70728S1809-68912022000100204S1809-68912022000100204.pdfSciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengCiência Animal Brasileirainfo:eu-repo/semantics/openAccess2023-12-26T06:17:17Zoai:repositorio.unesp.br:11449/236927Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-12-26T06:17:17Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Closure of defects in a geometric figure pattern associated with tumescent anesthesia with lidocaine in rabbits (Oryctolagus cuniculus) |
title |
Closure of defects in a geometric figure pattern associated with tumescent anesthesia with lidocaine in rabbits (Oryctolagus cuniculus) |
spellingShingle |
Closure of defects in a geometric figure pattern associated with tumescent anesthesia with lidocaine in rabbits (Oryctolagus cuniculus) Serafim, Eduardo Luís [UNESP] Local anesthetic Pain Reconstructive surgery Tissue repair |
title_short |
Closure of defects in a geometric figure pattern associated with tumescent anesthesia with lidocaine in rabbits (Oryctolagus cuniculus) |
title_full |
Closure of defects in a geometric figure pattern associated with tumescent anesthesia with lidocaine in rabbits (Oryctolagus cuniculus) |
title_fullStr |
Closure of defects in a geometric figure pattern associated with tumescent anesthesia with lidocaine in rabbits (Oryctolagus cuniculus) |
title_full_unstemmed |
Closure of defects in a geometric figure pattern associated with tumescent anesthesia with lidocaine in rabbits (Oryctolagus cuniculus) |
title_sort |
Closure of defects in a geometric figure pattern associated with tumescent anesthesia with lidocaine in rabbits (Oryctolagus cuniculus) |
author |
Serafim, Eduardo Luís [UNESP] |
author_facet |
Serafim, Eduardo Luís [UNESP] Pazzini, Josiane Morais [UNESP] Rocha, Michelle do Carmo Pereira [UNESP] Linhares, Laís Calazans Menescal [UNESP] Nardi, Andrigo Barboza de [UNESP] Gartner, Maria de Fátima Moutinho Amorim, Irina Rema, Alexandra Faria, Fátima Uscategui, Ricardo Andres Ramirez [UNESP] Almeida, Vivian Tavares De [UNESP] Calpaa, Carlos Alfredo Calazans, Sabrina Gouveia [UNESP] |
author_role |
author |
author2 |
Pazzini, Josiane Morais [UNESP] Rocha, Michelle do Carmo Pereira [UNESP] Linhares, Laís Calazans Menescal [UNESP] Nardi, Andrigo Barboza de [UNESP] Gartner, Maria de Fátima Moutinho Amorim, Irina Rema, Alexandra Faria, Fátima Uscategui, Ricardo Andres Ramirez [UNESP] Almeida, Vivian Tavares De [UNESP] Calpaa, Carlos Alfredo Calazans, Sabrina Gouveia [UNESP] |
author2_role |
author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Estadual Paulista (UNESP) Universidade do Porto (ICBAS-UP) Universidade de Natño |
dc.contributor.author.fl_str_mv |
Serafim, Eduardo Luís [UNESP] Pazzini, Josiane Morais [UNESP] Rocha, Michelle do Carmo Pereira [UNESP] Linhares, Laís Calazans Menescal [UNESP] Nardi, Andrigo Barboza de [UNESP] Gartner, Maria de Fátima Moutinho Amorim, Irina Rema, Alexandra Faria, Fátima Uscategui, Ricardo Andres Ramirez [UNESP] Almeida, Vivian Tavares De [UNESP] Calpaa, Carlos Alfredo Calazans, Sabrina Gouveia [UNESP] |
dc.subject.por.fl_str_mv |
Local anesthetic Pain Reconstructive surgery Tissue repair |
topic |
Local anesthetic Pain Reconstructive surgery Tissue repair |
description |
The use of tumescent anesthesia with lidocaine can provide better intra- and postoperative analgesia that would benefit extensive reconstructive surgery. However, lidocaine can interfere with the healing process. Therefore, this study aimed to assess the local interference of the healing of induced and closed skin defects in a geometric pattern associated with the use of tumescent anesthesia with lidocaine in rabbits. Furthermore, we assessed its influence on cardiorespiratory parameters and postoperative analgesia. This study included 27 rabbits divided into three groups: GC (without the use of tumescence), GS (use of tumescence with 0.9% NaCl solution), and GL (use of tumescent anesthesia with lidocaine). There was no statistically significant intergroup difference in any stage of the wound healing process on macroscopic evaluations, in the angiogenesis process, or in the process of collagenization and fibroblast deposition. There were significant differences in heart rate (lower in GL), respiratory rate (higher in GC), mean arterial pressure (higher in GL), and expired concentration of isoflurane (lower in GL). There was no significant intergroup difference in the von Frey filament test or the visual analog scale score used to evaluate postoperative analgesia. We concluded that tumescent anesthesia with lidocaine does not impair postoperative tissue repair. Its use features benefits such as reducing the volume of inhaled anesthetic, maintaining the anesthesia plan, stable heart and respiratory rates, and lower hypotension during the surgical procedure. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-10-10T13:56:15Z 2022-10-10T13:56:15Z 2022-04-06 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.1590/1809-6891v22e-7072e-70728 Ciência Animal Brasileira. Universidade Federal de Goiás, v. 23, p. -, 2022. 1518-2797 1809-6891 http://hdl.handle.net/11449/236927 10.1590/1809-6891v22e-7072e-70728 S1809-68912022000100204 S1809-68912022000100204.pdf |
url |
http://dx.doi.org/10.1590/1809-6891v22e-7072e-70728 http://hdl.handle.net/11449/236927 |
identifier_str_mv |
Ciência Animal Brasileira. Universidade Federal de Goiás, v. 23, p. -, 2022. 1518-2797 1809-6891 10.1590/1809-6891v22e-7072e-70728 S1809-68912022000100204 S1809-68912022000100204.pdf |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Ciência Animal Brasileira |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
- application/pdf |
dc.publisher.none.fl_str_mv |
Universidade Federal de Goiás |
publisher.none.fl_str_mv |
Universidade Federal de Goiás |
dc.source.none.fl_str_mv |
SciELO reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1797790113338490880 |