Effects of ropivacaine combined with morphine at 0.15 and 0.2 mg kg-1 in bitches undergoing epidural anesthesia
Autor(a) principal: | |
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Data de Publicação: | 2015 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015000300222&lng=en&nrm=iso&tlng=en http://hdl.handle.net/11449/127319 |
Resumo: | PURPOSE: To investigate cardiorespiratory effects and serum concentration of ropivacaine combined with morphine at different doses. METHODS: Sixteen healthy adult female dogs weighting 9.8±4.1 kg were included in the study. Twenty minutes after being premedicated with acepromazine and midazolam, the animals were randomly assigned to receive an epidural injection according to each group: RM0.15 = ropivacaine + morphine (0.15 mg kg-1) and RM0.2 = ropivacaine + morphine (0.2 mg kg-1). Variables recorded consisted of: heart rate and cardiac rhythm, respiratory rate, oxyhemoglobin saturation, inspired oxygen fraction, end-tidal carbon dioxide tension, systolic, mean and diastolic arterial pressures, serum cortisol, plasma ropivacaine and morphine. RESULTS: SAP, MAP and DAP were significantly increased at TPR in RM0.15 but returned to normal values at the end of the procedure. Arterial pH was decreased in T30 and TESu in both groups and also returned to acceptable ranges at TR. Both PaO2 and PaCO2 were increased along the duration period of the epidural blockade (T30 and TESu) and returned to acceptable values at TR. Serum cortisol was lower at TB, T30 and TR when compared to TESu. CONCLUSION: The procedures were performed safely and minimal changes in cardiovascular and respiratory variables. |
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Effects of ropivacaine combined with morphine at 0.15 and 0.2 mg kg-1 in bitches undergoing epidural anesthesiaAnalgesics, OpioidChromatography, high pressure LiquidHydrocortisoneDogsPURPOSE: To investigate cardiorespiratory effects and serum concentration of ropivacaine combined with morphine at different doses. METHODS: Sixteen healthy adult female dogs weighting 9.8±4.1 kg were included in the study. Twenty minutes after being premedicated with acepromazine and midazolam, the animals were randomly assigned to receive an epidural injection according to each group: RM0.15 = ropivacaine + morphine (0.15 mg kg-1) and RM0.2 = ropivacaine + morphine (0.2 mg kg-1). Variables recorded consisted of: heart rate and cardiac rhythm, respiratory rate, oxyhemoglobin saturation, inspired oxygen fraction, end-tidal carbon dioxide tension, systolic, mean and diastolic arterial pressures, serum cortisol, plasma ropivacaine and morphine. RESULTS: SAP, MAP and DAP were significantly increased at TPR in RM0.15 but returned to normal values at the end of the procedure. Arterial pH was decreased in T30 and TESu in both groups and also returned to acceptable ranges at TR. Both PaO2 and PaCO2 were increased along the duration period of the epidural blockade (T30 and TESu) and returned to acceptable values at TR. Serum cortisol was lower at TB, T30 and TR when compared to TESu. CONCLUSION: The procedures were performed safely and minimal changes in cardiovascular and respiratory variables.Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)Pró-Reitoria de Pesquisa (ProPe-Unesp)Federal University of Mato Grosso do Sul Faculty of Veterinary Medicine and Animal Science Department of Veterinary MedicineUFMS Faculty of Veterinary Medicine and Animal ScienceSao Paulo State University Faculty of Veterinary MedicineUNESPGaleno Reserch UnitUNESP Faculty of Veterinary Medicine Department of Clinical Surgery and Animal ReproductionSao Paulo State University Faculty of Veterinary MedicineUNESP Faculty of Veterinary Medicine Department of Clinical Surgery and Animal ReproductionFAPESP: 2006/09261Sociedade Brasileira para o Desenvolvimento da Pesquisa em CirurgiaUniversidade Federal do Mato Grosso do Sul (UFMS)Universidade Estadual Paulista (Unesp)Galeno Reserch UnitAlbuquerque, Verônica Batista deAraújo, Marcelo Augusto deFerreira, Gabriel Thadeu Nogueira Martins [UNESP]Fonseca, Mariana Werneck [UNESP]Arruda, André Moreira MartinsShichen, LuOliva, Valéria Nobre Leal de Souza [UNESP]2015-08-26T19:19:11Z2015-08-26T19:19:11Z2015-03-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article222-238application/pdfhttp://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015000300222&lng=en&nrm=iso&tlng=enActa Cirurgica Brasileira, v. 30, n. 3, p. 222-238, 2015.0102-8650http://hdl.handle.net/11449/12731910.1590/S0102-8650201500300000010S0102-86502015000300222S0102-86502015000300222.pdf0450092066822376SciELOreponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengActa Cirurgica Brasileira0.9330,395info:eu-repo/semantics/openAccess2023-12-10T06:16:39Zoai:repositorio.unesp.br:11449/127319Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462023-12-10T06:16:39Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Effects of ropivacaine combined with morphine at 0.15 and 0.2 mg kg-1 in bitches undergoing epidural anesthesia |
title |
Effects of ropivacaine combined with morphine at 0.15 and 0.2 mg kg-1 in bitches undergoing epidural anesthesia |
spellingShingle |
Effects of ropivacaine combined with morphine at 0.15 and 0.2 mg kg-1 in bitches undergoing epidural anesthesia Albuquerque, Verônica Batista de Analgesics, Opioid Chromatography, high pressure Liquid Hydrocortisone Dogs |
title_short |
Effects of ropivacaine combined with morphine at 0.15 and 0.2 mg kg-1 in bitches undergoing epidural anesthesia |
title_full |
Effects of ropivacaine combined with morphine at 0.15 and 0.2 mg kg-1 in bitches undergoing epidural anesthesia |
title_fullStr |
Effects of ropivacaine combined with morphine at 0.15 and 0.2 mg kg-1 in bitches undergoing epidural anesthesia |
title_full_unstemmed |
Effects of ropivacaine combined with morphine at 0.15 and 0.2 mg kg-1 in bitches undergoing epidural anesthesia |
title_sort |
Effects of ropivacaine combined with morphine at 0.15 and 0.2 mg kg-1 in bitches undergoing epidural anesthesia |
author |
Albuquerque, Verônica Batista de |
author_facet |
Albuquerque, Verônica Batista de Araújo, Marcelo Augusto de Ferreira, Gabriel Thadeu Nogueira Martins [UNESP] Fonseca, Mariana Werneck [UNESP] Arruda, André Moreira Martins Shichen, Lu Oliva, Valéria Nobre Leal de Souza [UNESP] |
author_role |
author |
author2 |
Araújo, Marcelo Augusto de Ferreira, Gabriel Thadeu Nogueira Martins [UNESP] Fonseca, Mariana Werneck [UNESP] Arruda, André Moreira Martins Shichen, Lu Oliva, Valéria Nobre Leal de Souza [UNESP] |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Universidade Federal do Mato Grosso do Sul (UFMS) Universidade Estadual Paulista (Unesp) Galeno Reserch Unit |
dc.contributor.author.fl_str_mv |
Albuquerque, Verônica Batista de Araújo, Marcelo Augusto de Ferreira, Gabriel Thadeu Nogueira Martins [UNESP] Fonseca, Mariana Werneck [UNESP] Arruda, André Moreira Martins Shichen, Lu Oliva, Valéria Nobre Leal de Souza [UNESP] |
dc.subject.por.fl_str_mv |
Analgesics, Opioid Chromatography, high pressure Liquid Hydrocortisone Dogs |
topic |
Analgesics, Opioid Chromatography, high pressure Liquid Hydrocortisone Dogs |
description |
PURPOSE: To investigate cardiorespiratory effects and serum concentration of ropivacaine combined with morphine at different doses. METHODS: Sixteen healthy adult female dogs weighting 9.8±4.1 kg were included in the study. Twenty minutes after being premedicated with acepromazine and midazolam, the animals were randomly assigned to receive an epidural injection according to each group: RM0.15 = ropivacaine + morphine (0.15 mg kg-1) and RM0.2 = ropivacaine + morphine (0.2 mg kg-1). Variables recorded consisted of: heart rate and cardiac rhythm, respiratory rate, oxyhemoglobin saturation, inspired oxygen fraction, end-tidal carbon dioxide tension, systolic, mean and diastolic arterial pressures, serum cortisol, plasma ropivacaine and morphine. RESULTS: SAP, MAP and DAP were significantly increased at TPR in RM0.15 but returned to normal values at the end of the procedure. Arterial pH was decreased in T30 and TESu in both groups and also returned to acceptable ranges at TR. Both PaO2 and PaCO2 were increased along the duration period of the epidural blockade (T30 and TESu) and returned to acceptable values at TR. Serum cortisol was lower at TB, T30 and TR when compared to TESu. CONCLUSION: The procedures were performed safely and minimal changes in cardiovascular and respiratory variables. |
publishDate |
2015 |
dc.date.none.fl_str_mv |
2015-08-26T19:19:11Z 2015-08-26T19:19:11Z 2015-03-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015000300222&lng=en&nrm=iso&tlng=en Acta Cirurgica Brasileira, v. 30, n. 3, p. 222-238, 2015. 0102-8650 http://hdl.handle.net/11449/127319 10.1590/S0102-8650201500300000010 S0102-86502015000300222 S0102-86502015000300222.pdf 0450092066822376 |
url |
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015000300222&lng=en&nrm=iso&tlng=en http://hdl.handle.net/11449/127319 |
identifier_str_mv |
Acta Cirurgica Brasileira, v. 30, n. 3, p. 222-238, 2015. 0102-8650 10.1590/S0102-8650201500300000010 S0102-86502015000300222 S0102-86502015000300222.pdf 0450092066822376 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Acta Cirurgica Brasileira 0.933 0,395 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
222-238 application/pdf |
dc.publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
publisher.none.fl_str_mv |
Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia |
dc.source.none.fl_str_mv |
SciELO reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
_version_ |
1799965232895885312 |