Visceral mycobacteriosis in amphibians from the Brazilian Caatinga region
Autor(a) principal: | |
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Data de Publicação: | 2021 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Institucional da UNESP |
Texto Completo: | http://dx.doi.org/10.3354/dao03604 http://hdl.handle.net/11449/218648 |
Resumo: | Emerging infectious diseases in wild animals related to humans have received greater attention in recent years. Mycobacteriosis is a bacterial disease of animal and human importance. Mycobacterium gordonae infects the skin and internal organs of free-ranging amphibians and is considered the least pathogenic member of the Mycobacteriaceae to humans. However, information about its infection and pathogenesis in wild amphibians is still lacking. A total of 1306 amphibian specimens belonging to 6 families, 12 genera, and 21 species were collected and dissected during a helminthological survey of 7 municipalities in southern Ceara state, Caatinga (eco)region, northeast Brazil. Of these, 17 specimens (0.76%), belonging to 2 families and 4 species (Leptodactylus macrosternum, n = 2; L. vastus, n = 10; Pseudopaludicola pocoto, n = 2; Rhinella jimi, n = 3), presented infections that consisted of calcification nodules in the coelomic cavity, kidney, liver, lung, gut, and pancreas. The nodules were examined by histopathology and PCR. The bacteria were identified as M. gordonae by molecular analyses. Infected animals presented with hepatocellular vacuolar degeneration, karyolysis, and karyorrhexis, hepatic portal congestion, hemorrhage, mononuclear cellular infiltration, melanomacrophage center hyperplasia, and granulomas in varying stages of development with intralesional acid-fast bacilli. This study is the first report of M. gordonae in these amphibian species, in which results of molecular analyses confirmed the presence of M. gordonae in natural environments and histopathology confirmed the typical lesion of mycobacteriosis in amphibians from northeastern Brazil. |
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Visceral mycobacteriosis in amphibians from the Brazilian Caatinga regionMycobacteriaMycobacterium gordonaeAmphibian diseasesMolecular diagnosisHistopathologyPathogenicWild animalsConservationEmerging infectious diseases in wild animals related to humans have received greater attention in recent years. Mycobacteriosis is a bacterial disease of animal and human importance. Mycobacterium gordonae infects the skin and internal organs of free-ranging amphibians and is considered the least pathogenic member of the Mycobacteriaceae to humans. However, information about its infection and pathogenesis in wild amphibians is still lacking. A total of 1306 amphibian specimens belonging to 6 families, 12 genera, and 21 species were collected and dissected during a helminthological survey of 7 municipalities in southern Ceara state, Caatinga (eco)region, northeast Brazil. Of these, 17 specimens (0.76%), belonging to 2 families and 4 species (Leptodactylus macrosternum, n = 2; L. vastus, n = 10; Pseudopaludicola pocoto, n = 2; Rhinella jimi, n = 3), presented infections that consisted of calcification nodules in the coelomic cavity, kidney, liver, lung, gut, and pancreas. The nodules were examined by histopathology and PCR. The bacteria were identified as M. gordonae by molecular analyses. Infected animals presented with hepatocellular vacuolar degeneration, karyolysis, and karyorrhexis, hepatic portal congestion, hemorrhage, mononuclear cellular infiltration, melanomacrophage center hyperplasia, and granulomas in varying stages of development with intralesional acid-fast bacilli. This study is the first report of M. gordonae in these amphibian species, in which results of molecular analyses confirmed the presence of M. gordonae in natural environments and histopathology confirmed the typical lesion of mycobacteriosis in amphibians from northeastern Brazil.Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Fundacao Cearense de Apoio ao Desenvolvimento Cientifico e Tecnologico - FUNCAPUniv Fed Uberlandia UFU, Inst Ciencias Agr, BR-38500000 Monte Carmelo, MG, BrazilUniv Estadual Paulista UNESP, Dept Parasitol, Inst Biociencias, BR-18618970 Botucatu, SP, BrazilUniv Fed Ceara UFC, Ctr Reg Ophiol, BR-60455760 Fortaleza, Ceara, BrazilUniv Estadual Paulista UNESP, Dept Parasitol, Inst Biociencias, BR-18618970 Botucatu, SP, BrazilCNPq: 303622/2015-6CNPq: 305988/2018-2CNPq: 313241/2018-0Fundacao Cearense de Apoio ao Desenvolvimento Cientifico e Tecnologico - FUNCAP: AEP-0128-00269.01.00/17Fundacao Cearense de Apoio ao Desenvolvimento Cientifico e Tecnologico - FUNCAP: 05/2017Inter-researchUniv Fed Uberlandia UFUUniversidade Estadual Paulista (UNESP)Univ Fed Ceara UFCMorais, Drausio HonorioRodrigues, Marianna Vaz [UNESP]Avila, Robson WaldemarSilva, Reinaldo Jose da [UNESP]2022-04-28T17:22:08Z2022-04-28T17:22:08Z2021-01-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article139-144http://dx.doi.org/10.3354/dao03604Diseases Of Aquatic Organisms. Oldendorf Luhe: Inter-research, v. 145, p. 139-144, 2021.0177-5103http://hdl.handle.net/11449/21864810.3354/dao03604WOS:000691780800012Web of Sciencereponame:Repositório Institucional da UNESPinstname:Universidade Estadual Paulista (UNESP)instacron:UNESPengDiseases Of Aquatic Organismsinfo:eu-repo/semantics/openAccess2022-04-28T17:22:08Zoai:repositorio.unesp.br:11449/218648Repositório InstitucionalPUBhttp://repositorio.unesp.br/oai/requestopendoar:29462022-04-28T17:22:08Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP)false |
dc.title.none.fl_str_mv |
Visceral mycobacteriosis in amphibians from the Brazilian Caatinga region |
title |
Visceral mycobacteriosis in amphibians from the Brazilian Caatinga region |
spellingShingle |
Visceral mycobacteriosis in amphibians from the Brazilian Caatinga region Morais, Drausio Honorio Mycobacteria Mycobacterium gordonae Amphibian diseases Molecular diagnosis Histopathology Pathogenic Wild animals Conservation |
title_short |
Visceral mycobacteriosis in amphibians from the Brazilian Caatinga region |
title_full |
Visceral mycobacteriosis in amphibians from the Brazilian Caatinga region |
title_fullStr |
Visceral mycobacteriosis in amphibians from the Brazilian Caatinga region |
title_full_unstemmed |
Visceral mycobacteriosis in amphibians from the Brazilian Caatinga region |
title_sort |
Visceral mycobacteriosis in amphibians from the Brazilian Caatinga region |
author |
Morais, Drausio Honorio |
author_facet |
Morais, Drausio Honorio Rodrigues, Marianna Vaz [UNESP] Avila, Robson Waldemar Silva, Reinaldo Jose da [UNESP] |
author_role |
author |
author2 |
Rodrigues, Marianna Vaz [UNESP] Avila, Robson Waldemar Silva, Reinaldo Jose da [UNESP] |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Univ Fed Uberlandia UFU Universidade Estadual Paulista (UNESP) Univ Fed Ceara UFC |
dc.contributor.author.fl_str_mv |
Morais, Drausio Honorio Rodrigues, Marianna Vaz [UNESP] Avila, Robson Waldemar Silva, Reinaldo Jose da [UNESP] |
dc.subject.por.fl_str_mv |
Mycobacteria Mycobacterium gordonae Amphibian diseases Molecular diagnosis Histopathology Pathogenic Wild animals Conservation |
topic |
Mycobacteria Mycobacterium gordonae Amphibian diseases Molecular diagnosis Histopathology Pathogenic Wild animals Conservation |
description |
Emerging infectious diseases in wild animals related to humans have received greater attention in recent years. Mycobacteriosis is a bacterial disease of animal and human importance. Mycobacterium gordonae infects the skin and internal organs of free-ranging amphibians and is considered the least pathogenic member of the Mycobacteriaceae to humans. However, information about its infection and pathogenesis in wild amphibians is still lacking. A total of 1306 amphibian specimens belonging to 6 families, 12 genera, and 21 species were collected and dissected during a helminthological survey of 7 municipalities in southern Ceara state, Caatinga (eco)region, northeast Brazil. Of these, 17 specimens (0.76%), belonging to 2 families and 4 species (Leptodactylus macrosternum, n = 2; L. vastus, n = 10; Pseudopaludicola pocoto, n = 2; Rhinella jimi, n = 3), presented infections that consisted of calcification nodules in the coelomic cavity, kidney, liver, lung, gut, and pancreas. The nodules were examined by histopathology and PCR. The bacteria were identified as M. gordonae by molecular analyses. Infected animals presented with hepatocellular vacuolar degeneration, karyolysis, and karyorrhexis, hepatic portal congestion, hemorrhage, mononuclear cellular infiltration, melanomacrophage center hyperplasia, and granulomas in varying stages of development with intralesional acid-fast bacilli. This study is the first report of M. gordonae in these amphibian species, in which results of molecular analyses confirmed the presence of M. gordonae in natural environments and histopathology confirmed the typical lesion of mycobacteriosis in amphibians from northeastern Brazil. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-01-01 2022-04-28T17:22:08Z 2022-04-28T17:22:08Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://dx.doi.org/10.3354/dao03604 Diseases Of Aquatic Organisms. Oldendorf Luhe: Inter-research, v. 145, p. 139-144, 2021. 0177-5103 http://hdl.handle.net/11449/218648 10.3354/dao03604 WOS:000691780800012 |
url |
http://dx.doi.org/10.3354/dao03604 http://hdl.handle.net/11449/218648 |
identifier_str_mv |
Diseases Of Aquatic Organisms. Oldendorf Luhe: Inter-research, v. 145, p. 139-144, 2021. 0177-5103 10.3354/dao03604 WOS:000691780800012 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Diseases Of Aquatic Organisms |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
139-144 |
dc.publisher.none.fl_str_mv |
Inter-research |
publisher.none.fl_str_mv |
Inter-research |
dc.source.none.fl_str_mv |
Web of Science reponame:Repositório Institucional da UNESP instname:Universidade Estadual Paulista (UNESP) instacron:UNESP |
instname_str |
Universidade Estadual Paulista (UNESP) |
instacron_str |
UNESP |
institution |
UNESP |
reponame_str |
Repositório Institucional da UNESP |
collection |
Repositório Institucional da UNESP |
repository.name.fl_str_mv |
Repositório Institucional da UNESP - Universidade Estadual Paulista (UNESP) |
repository.mail.fl_str_mv |
|
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1799965200764370944 |