Uso de nutracêuticos na prevenção da degeneração do disco intervertebral em cães da raça dachshund miniatura

• Autor(a) principal: BARAÚNA JÚNIOR, Durval
• Data de Publicação: 2016
• Tipo de documento: Tese
• Idioma: por
• Título da fonte: Biblioteca Digital de Teses e Dissertações da UFRPE
• Texto Completo: http://www.tede2.ufrpe.br:8080/tede2/handle/tede2/5179
• topic: Disco intervertebral; Cão; Medula espinal; Coluna vertebral; Condroprotetor; Intervertebral disc; Dog; Spinal cord; Spine; Chondroprotector; CIENCIAS AGRARIAS::MEDICINA VETERINARIA

The intervertebral disc disease is the most common cause of myelopathy in dogs. The objective of this research is describe the tomographic imaging of intervertebral discs mineralized in Miniature Dachshund dogs with one year old and check the effect of supplementation with nutraceuticals in preventing chondroid degeneration and mineralization of IVD. Twenty puppies four months old were held for eight months in kennels with access to light. Twenty puppies divided into two groups of ten and submitted to two treatments for 240 days Nutraceuticals group (NG) received a tablet, per day, by oral route, containing chondroitin sulfate, glucosamine sulfate, manganese, sulfur, DL-methionine. Control group (CG) received a tablet, daily containing only excipient. Of the 70 disks evaluated in CG, 45 were considered as altered. In altered, location was determined in eight disks (17.77%) in nucleus pulposus, nine discs (20%) in fibrous ring and 28 discs (62, 23%) this change was in entire disk. Comparing the groups, the percentage of animals classified as calcification was higher in the CG than in NG (64.3% vs. 44.3%), a difference that for fixed margin of error (5%) was significant between the groups, with respect to present bonus (p <0.05 relative risk 1.45 interval that excludes the value 1.00). In NG the highest frequency mineralization occurred in T9-10 (70,0%), T11-12 (50,0%) e T13-L1 (50,0%) and in CG in the discs T9-10 (90,0%) e T10-11 (80,0%). This study proposes the use of the association between manganese, glucosamine and chondroitin sulfates generated less mineralized intervertebral discs.