Histomorphometric analysis of the repair process of autogenous bone grafts fixed at rat calvaria with cyanoacrylate
Autor(a) principal: | |
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Data de Publicação: | 2011 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Journal of applied oral science (Online) |
Texto Completo: | https://www.revistas.usp.br/jaos/article/view/3949 |
Resumo: | OBJECTIVE: The purpose of this study was to perform histological and histometric analyses of the repair process of autogenous bone grafts fixed at rat calvaria with ethyl-cyanoacrylate adhesive. MATERIAL AND METHODS: Thirty-two rats were divided into two groups (n=16), Group I - Control and Group II - Adhesive. Osteotomies were made at the right parietal bone for graft obtainment using a 4-mm-diameter trephine drill. Then, the bone segments were fixed with the adhesive in the parietal region of the opposite side to the donor site. After 10 and 30 days, 8 animals of each group were euthanized and the calvarias were laboratorially processed for obtaining hematoxylin and eosin-stained slides for histological and histometric analyses. RESULTS: An intense inflammatory reaction was observed at the 10-day period. At 30 days, this reaction was less intense, despite the presence of adhesive at the recipient-site/graft interface. Graft incorporation to the recipient site was observed only at the control group, which maintained the highest graft size at 10 and 30 days. CONCLUSIONS: Although the fragment was stable, the presence of adhesive in Group II did not allow graft incorporation to the recipient site, determining a localized, discrete and persistent inflammatory reaction. |
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Journal of applied oral science (Online) |
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Histomorphometric analysis of the repair process of autogenous bone grafts fixed at rat calvaria with cyanoacrylate Tissue adhesivesCyanoacrylatesBone transplantation OBJECTIVE: The purpose of this study was to perform histological and histometric analyses of the repair process of autogenous bone grafts fixed at rat calvaria with ethyl-cyanoacrylate adhesive. MATERIAL AND METHODS: Thirty-two rats were divided into two groups (n=16), Group I - Control and Group II - Adhesive. Osteotomies were made at the right parietal bone for graft obtainment using a 4-mm-diameter trephine drill. Then, the bone segments were fixed with the adhesive in the parietal region of the opposite side to the donor site. After 10 and 30 days, 8 animals of each group were euthanized and the calvarias were laboratorially processed for obtaining hematoxylin and eosin-stained slides for histological and histometric analyses. RESULTS: An intense inflammatory reaction was observed at the 10-day period. At 30 days, this reaction was less intense, despite the presence of adhesive at the recipient-site/graft interface. Graft incorporation to the recipient site was observed only at the control group, which maintained the highest graft size at 10 and 30 days. CONCLUSIONS: Although the fragment was stable, the presence of adhesive in Group II did not allow graft incorporation to the recipient site, determining a localized, discrete and persistent inflammatory reaction. Universidade de São Paulo. Faculdade de Odontologia de Bauru2011-10-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/jaos/article/view/394910.1590/S1678-77572011000500016Journal of Applied Oral Science; Vol. 19 No. 5 (2011); 529-534 Journal of Applied Oral Science; Vol. 19 Núm. 5 (2011); 529-534 Journal of Applied Oral Science; v. 19 n. 5 (2011); 529-534 1678-77651678-7757reponame:Journal of applied oral science (Online)instname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/jaos/article/view/3949/4639Copyright (c) 2011 Journal of Applied Oral Scienceinfo:eu-repo/semantics/openAccessEsteves, Jônatas CaldeiraBorrasca, Albanir GabrielAranega, Alessandra MarcondesGarcia Junior, Idelmo RangelMagro Filho, Osvaldo2012-04-27T12:15:50Zoai:revistas.usp.br:article/3949Revistahttp://www.scielo.br/jaosPUBhttps://www.revistas.usp.br/jaos/oai||jaos@usp.br1678-77651678-7757opendoar:2012-04-27T12:15:50Journal of applied oral science (Online) - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Histomorphometric analysis of the repair process of autogenous bone grafts fixed at rat calvaria with cyanoacrylate |
title |
Histomorphometric analysis of the repair process of autogenous bone grafts fixed at rat calvaria with cyanoacrylate |
spellingShingle |
Histomorphometric analysis of the repair process of autogenous bone grafts fixed at rat calvaria with cyanoacrylate Esteves, Jônatas Caldeira Tissue adhesives Cyanoacrylates Bone transplantation |
title_short |
Histomorphometric analysis of the repair process of autogenous bone grafts fixed at rat calvaria with cyanoacrylate |
title_full |
Histomorphometric analysis of the repair process of autogenous bone grafts fixed at rat calvaria with cyanoacrylate |
title_fullStr |
Histomorphometric analysis of the repair process of autogenous bone grafts fixed at rat calvaria with cyanoacrylate |
title_full_unstemmed |
Histomorphometric analysis of the repair process of autogenous bone grafts fixed at rat calvaria with cyanoacrylate |
title_sort |
Histomorphometric analysis of the repair process of autogenous bone grafts fixed at rat calvaria with cyanoacrylate |
author |
Esteves, Jônatas Caldeira |
author_facet |
Esteves, Jônatas Caldeira Borrasca, Albanir Gabriel Aranega, Alessandra Marcondes Garcia Junior, Idelmo Rangel Magro Filho, Osvaldo |
author_role |
author |
author2 |
Borrasca, Albanir Gabriel Aranega, Alessandra Marcondes Garcia Junior, Idelmo Rangel Magro Filho, Osvaldo |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Esteves, Jônatas Caldeira Borrasca, Albanir Gabriel Aranega, Alessandra Marcondes Garcia Junior, Idelmo Rangel Magro Filho, Osvaldo |
dc.subject.por.fl_str_mv |
Tissue adhesives Cyanoacrylates Bone transplantation |
topic |
Tissue adhesives Cyanoacrylates Bone transplantation |
description |
OBJECTIVE: The purpose of this study was to perform histological and histometric analyses of the repair process of autogenous bone grafts fixed at rat calvaria with ethyl-cyanoacrylate adhesive. MATERIAL AND METHODS: Thirty-two rats were divided into two groups (n=16), Group I - Control and Group II - Adhesive. Osteotomies were made at the right parietal bone for graft obtainment using a 4-mm-diameter trephine drill. Then, the bone segments were fixed with the adhesive in the parietal region of the opposite side to the donor site. After 10 and 30 days, 8 animals of each group were euthanized and the calvarias were laboratorially processed for obtaining hematoxylin and eosin-stained slides for histological and histometric analyses. RESULTS: An intense inflammatory reaction was observed at the 10-day period. At 30 days, this reaction was less intense, despite the presence of adhesive at the recipient-site/graft interface. Graft incorporation to the recipient site was observed only at the control group, which maintained the highest graft size at 10 and 30 days. CONCLUSIONS: Although the fragment was stable, the presence of adhesive in Group II did not allow graft incorporation to the recipient site, determining a localized, discrete and persistent inflammatory reaction. |
publishDate |
2011 |
dc.date.none.fl_str_mv |
2011-10-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/3949 10.1590/S1678-77572011000500016 |
url |
https://www.revistas.usp.br/jaos/article/view/3949 |
identifier_str_mv |
10.1590/S1678-77572011000500016 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/jaos/article/view/3949/4639 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2011 Journal of Applied Oral Science info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2011 Journal of Applied Oral Science |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
publisher.none.fl_str_mv |
Universidade de São Paulo. Faculdade de Odontologia de Bauru |
dc.source.none.fl_str_mv |
Journal of Applied Oral Science; Vol. 19 No. 5 (2011); 529-534 Journal of Applied Oral Science; Vol. 19 Núm. 5 (2011); 529-534 Journal of Applied Oral Science; v. 19 n. 5 (2011); 529-534 1678-7765 1678-7757 reponame:Journal of applied oral science (Online) instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Journal of applied oral science (Online) |
collection |
Journal of applied oral science (Online) |
repository.name.fl_str_mv |
Journal of applied oral science (Online) - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||jaos@usp.br |
_version_ |
1800221676866109440 |