Edema e malignidade em meningiomas
Autor(a) principal: | |
---|---|
Data de Publicação: | 2005 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Clinics |
Texto Completo: | https://www.revistas.usp.br/clinics/article/view/17429 |
Resumo: | PURPOSE: In recent years there have been many attempts to define a subset of aggressive malignant meningiomas based on histopathology and imaging technologies. The purpose of this study was to evaluate the level of peritumoral edema and its volume using the imaging technologies, computer tomography and magnetic resonance imaging, and correlate these results with the histological WHO classification. Reported causes of tumoral edema and its relationships to the histological characteristics were also reviewed. METHODS: The cases of 55 patients with meningiomas who underwent surgery at the Hospital das Clinicas (Fac Med Univ Sao Paulo) between September 1993 and September 1997 were reviewed. The level of edema according to the classification of Ide et al. (1995) was compared to the histological WHO classification. RESULTS: Classification of the degree of edema was: level 0 edema - 28 cases ; level I edema - 19 cases; level II edema - 8 cases. Histological classification was: benign meningioma - 43 cases; atypical meningiomas - 11 cases; malignant meningioma - 1 case. There was a significant (P = .0089) correlation between the degree of tumoral edema and the histological characteristics. CONCLUSIONS: These results suggest that the degree of edema as revealed by computer tomography and magnetic resonance imaging can be an important clinical predictive factor for the histological grade of the meningioma. |
id |
USP-19_328291dd2311cb6e4aa6543508c7e92a |
---|---|
oai_identifier_str |
oai:revistas.usp.br:article/17429 |
network_acronym_str |
USP-19 |
network_name_str |
Clinics |
repository_id_str |
|
spelling |
Edema e malignidade em meningiomas Edema and malignancy in meningiomas EdemaMeningiomaMeningiomas malignosRessonância nuclear magnéticaTomografia computadorizadaEdemaMeningiomaMalignant meningiomasMagnetic resonance imagingComputed tomographic scan PURPOSE: In recent years there have been many attempts to define a subset of aggressive malignant meningiomas based on histopathology and imaging technologies. The purpose of this study was to evaluate the level of peritumoral edema and its volume using the imaging technologies, computer tomography and magnetic resonance imaging, and correlate these results with the histological WHO classification. Reported causes of tumoral edema and its relationships to the histological characteristics were also reviewed. METHODS: The cases of 55 patients with meningiomas who underwent surgery at the Hospital das Clinicas (Fac Med Univ Sao Paulo) between September 1993 and September 1997 were reviewed. The level of edema according to the classification of Ide et al. (1995) was compared to the histological WHO classification. RESULTS: Classification of the degree of edema was: level 0 edema - 28 cases ; level I edema - 19 cases; level II edema - 8 cases. Histological classification was: benign meningioma - 43 cases; atypical meningiomas - 11 cases; malignant meningioma - 1 case. There was a significant (P = .0089) correlation between the degree of tumoral edema and the histological characteristics. CONCLUSIONS: These results suggest that the degree of edema as revealed by computer tomography and magnetic resonance imaging can be an important clinical predictive factor for the histological grade of the meningioma. OBJETIVO: Nos últimos anos têm-se descrito alguns subtipos de meningiomas de comportamento peculiarmente agressivo. Muitas tentativas têm sido feitas no intuito de estabelecer critérios imagenológicos ou histopatológicos de malignidade. O objetivo desse estudo é avaliar, através de Tomografia Computadorizada e Ressonância Nuclear Magnética o grau de edema peritumoral e seu volume, correlacionando-os com a classificação histológica da OMS. As causas relatadas de edema peritumoral e sua possível correlação histológica foram também revistos. MÉTODOS: Foram estudados 55 casos de meningiomas operados no Hospital das Clinicas (FMUSP) entre Setembro de 1993 e Setembro de 1997. O grau de edema segundo a classificação de Ide et al. (1995) foi comparado com a classificação da OMS. RESULTADOS: Os achados relativos a edema foram: edema grau 0 - 28 pacientes; grau I - 19 pacientes; grau II - 8 pacientes. A classificação histológica demonstrou: meningiomas benignos - 43 casos; meningiomas atípicos - 11 casos meningioma maligno - 1 caso. Demonstrou-se uma correlação significativa (p = 0,0089) entre o grau de edema dos meningiomas e suas características histológicas. CONCLUSÕES: Esses resultados sugerem que o grau de edema avaliado imagenologicamente pela Tomografia Computadorizada e Ressonância Nuclear Magnética pode ser um importante fator preditivo da gradação histológica dos meningiomas. Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2005-06-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/1742910.1590/S1807-59322005000300004Clinics; v. 60 n. 3 (2005); 201-206 Clinics; Vol. 60 Núm. 3 (2005); 201-206 Clinics; Vol. 60 No. 3 (2005); 201-206 1980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/17429/19479Mattei, Tobias AlécioMattei, Josias AlécioRamina, RicardoAguiar, Paulo HenriquePlese, José PindaroMarino Jr, Raulinfo:eu-repo/semantics/openAccess2012-05-22T17:59:20Zoai:revistas.usp.br:article/17429Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2012-05-22T17:59:20Clinics - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
Edema e malignidade em meningiomas Edema and malignancy in meningiomas |
title |
Edema e malignidade em meningiomas |
spellingShingle |
Edema e malignidade em meningiomas Mattei, Tobias Alécio Edema Meningioma Meningiomas malignos Ressonância nuclear magnética Tomografia computadorizada Edema Meningioma Malignant meningiomas Magnetic resonance imaging Computed tomographic scan |
title_short |
Edema e malignidade em meningiomas |
title_full |
Edema e malignidade em meningiomas |
title_fullStr |
Edema e malignidade em meningiomas |
title_full_unstemmed |
Edema e malignidade em meningiomas |
title_sort |
Edema e malignidade em meningiomas |
author |
Mattei, Tobias Alécio |
author_facet |
Mattei, Tobias Alécio Mattei, Josias Alécio Ramina, Ricardo Aguiar, Paulo Henrique Plese, José Pindaro Marino Jr, Raul |
author_role |
author |
author2 |
Mattei, Josias Alécio Ramina, Ricardo Aguiar, Paulo Henrique Plese, José Pindaro Marino Jr, Raul |
author2_role |
author author author author author |
dc.contributor.author.fl_str_mv |
Mattei, Tobias Alécio Mattei, Josias Alécio Ramina, Ricardo Aguiar, Paulo Henrique Plese, José Pindaro Marino Jr, Raul |
dc.subject.por.fl_str_mv |
Edema Meningioma Meningiomas malignos Ressonância nuclear magnética Tomografia computadorizada Edema Meningioma Malignant meningiomas Magnetic resonance imaging Computed tomographic scan |
topic |
Edema Meningioma Meningiomas malignos Ressonância nuclear magnética Tomografia computadorizada Edema Meningioma Malignant meningiomas Magnetic resonance imaging Computed tomographic scan |
description |
PURPOSE: In recent years there have been many attempts to define a subset of aggressive malignant meningiomas based on histopathology and imaging technologies. The purpose of this study was to evaluate the level of peritumoral edema and its volume using the imaging technologies, computer tomography and magnetic resonance imaging, and correlate these results with the histological WHO classification. Reported causes of tumoral edema and its relationships to the histological characteristics were also reviewed. METHODS: The cases of 55 patients with meningiomas who underwent surgery at the Hospital das Clinicas (Fac Med Univ Sao Paulo) between September 1993 and September 1997 were reviewed. The level of edema according to the classification of Ide et al. (1995) was compared to the histological WHO classification. RESULTS: Classification of the degree of edema was: level 0 edema - 28 cases ; level I edema - 19 cases; level II edema - 8 cases. Histological classification was: benign meningioma - 43 cases; atypical meningiomas - 11 cases; malignant meningioma - 1 case. There was a significant (P = .0089) correlation between the degree of tumoral edema and the histological characteristics. CONCLUSIONS: These results suggest that the degree of edema as revealed by computer tomography and magnetic resonance imaging can be an important clinical predictive factor for the histological grade of the meningioma. |
publishDate |
2005 |
dc.date.none.fl_str_mv |
2005-06-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/17429 10.1590/S1807-59322005000300004 |
url |
https://www.revistas.usp.br/clinics/article/view/17429 |
identifier_str_mv |
10.1590/S1807-59322005000300004 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/17429/19479 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
dc.source.none.fl_str_mv |
Clinics; v. 60 n. 3 (2005); 201-206 Clinics; Vol. 60 Núm. 3 (2005); 201-206 Clinics; Vol. 60 No. 3 (2005); 201-206 1980-5322 1807-5932 reponame:Clinics instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Clinics |
collection |
Clinics |
repository.name.fl_str_mv |
Clinics - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||clinics@hc.fm.usp.br |
_version_ |
1787713167174926336 |