The Lowest Prevalence of Cholelithiasis in the Americas - An Autopsy-based Study
Autor(a) principal: | |
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Data de Publicação: | 2016 |
Outros Autores: | , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Clinics |
Texto Completo: | https://www.revistas.usp.br/clinics/article/view/118025 |
Resumo: | OBJECTIVES: This study used autopsy to evaluate the prevalence of cholelithiasis and its associated risk factors in a population of healthy, young subjects who suffered a violent or natural death. METHODS: This study is a prospective evaluation of autopsies of 446 individuals from 2011 to 2013 in Brazil. Of that sample, 330 (74%) subjects died from violent deaths and 116 (26%) died naturally. The presence of biliary calculi, previous cholecystectomy, gender, age, ethnicity, body mass index (BMI) and alcohol use were evaluated. RESULTS: In the natural death group, 6.9% (95% CI 3.39 to 13.28) (3.08% of the male subjects and 11.76% of the female subjects) exhibited evidence of gallbladder disease. In the violent death group, only 2.12% (95% CI 0.96 to 4.43) (2.17% of the male subjects and 1.85% of the female subjects) of the subjects exhibited evidence of gallbladder disease. Age was correlated with the prevalence of gallbladder disease, but BMI was correlated with only gallbladder disease in the natural death group. CONCLUSIONS: This population has the lowest prevalence of cholelithiasis in the Americas. Dietary habits, physical activity, ethnicity, alcohol consumption and genetic factors may be responsible for this low prevalence. |
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Clinics |
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The Lowest Prevalence of Cholelithiasis in the Americas - An Autopsy-based Study OBJECTIVES: This study used autopsy to evaluate the prevalence of cholelithiasis and its associated risk factors in a population of healthy, young subjects who suffered a violent or natural death. METHODS: This study is a prospective evaluation of autopsies of 446 individuals from 2011 to 2013 in Brazil. Of that sample, 330 (74%) subjects died from violent deaths and 116 (26%) died naturally. The presence of biliary calculi, previous cholecystectomy, gender, age, ethnicity, body mass index (BMI) and alcohol use were evaluated. RESULTS: In the natural death group, 6.9% (95% CI 3.39 to 13.28) (3.08% of the male subjects and 11.76% of the female subjects) exhibited evidence of gallbladder disease. In the violent death group, only 2.12% (95% CI 0.96 to 4.43) (2.17% of the male subjects and 1.85% of the female subjects) of the subjects exhibited evidence of gallbladder disease. Age was correlated with the prevalence of gallbladder disease, but BMI was correlated with only gallbladder disease in the natural death group. CONCLUSIONS: This population has the lowest prevalence of cholelithiasis in the Americas. Dietary habits, physical activity, ethnicity, alcohol consumption and genetic factors may be responsible for this low prevalence. Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2016-07-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/11802510.6061/clinics/2016(07)02Clinics; v. 71 n. 7 (2016); 365-369 Clinics; Vol. 71 Núm. 7 (2016); 365-369 Clinics; Vol. 71 No. 7 (2016); 365-369 1980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/118025/115649Copyright (c) 2016 Clinicsinfo:eu-repo/semantics/openAccessAsperti, André MarangoniReis, PauloDiniz, Marcio AugustoPinto, Mariana DouradoSilva Júnior, Edinésio Carlos daSilva, Danilo Felipe Dias daD’Albuquerque, Luiz Augusto CarneiroAndraus, Wellington2016-07-21T17:00:41Zoai:revistas.usp.br:article/118025Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2016-07-21T17:00:41Clinics - Universidade de São Paulo (USP)false |
dc.title.none.fl_str_mv |
The Lowest Prevalence of Cholelithiasis in the Americas - An Autopsy-based Study |
title |
The Lowest Prevalence of Cholelithiasis in the Americas - An Autopsy-based Study |
spellingShingle |
The Lowest Prevalence of Cholelithiasis in the Americas - An Autopsy-based Study Asperti, André Marangoni |
title_short |
The Lowest Prevalence of Cholelithiasis in the Americas - An Autopsy-based Study |
title_full |
The Lowest Prevalence of Cholelithiasis in the Americas - An Autopsy-based Study |
title_fullStr |
The Lowest Prevalence of Cholelithiasis in the Americas - An Autopsy-based Study |
title_full_unstemmed |
The Lowest Prevalence of Cholelithiasis in the Americas - An Autopsy-based Study |
title_sort |
The Lowest Prevalence of Cholelithiasis in the Americas - An Autopsy-based Study |
author |
Asperti, André Marangoni |
author_facet |
Asperti, André Marangoni Reis, Paulo Diniz, Marcio Augusto Pinto, Mariana Dourado Silva Júnior, Edinésio Carlos da Silva, Danilo Felipe Dias da D’Albuquerque, Luiz Augusto Carneiro Andraus, Wellington |
author_role |
author |
author2 |
Reis, Paulo Diniz, Marcio Augusto Pinto, Mariana Dourado Silva Júnior, Edinésio Carlos da Silva, Danilo Felipe Dias da D’Albuquerque, Luiz Augusto Carneiro Andraus, Wellington |
author2_role |
author author author author author author author |
dc.contributor.author.fl_str_mv |
Asperti, André Marangoni Reis, Paulo Diniz, Marcio Augusto Pinto, Mariana Dourado Silva Júnior, Edinésio Carlos da Silva, Danilo Felipe Dias da D’Albuquerque, Luiz Augusto Carneiro Andraus, Wellington |
description |
OBJECTIVES: This study used autopsy to evaluate the prevalence of cholelithiasis and its associated risk factors in a population of healthy, young subjects who suffered a violent or natural death. METHODS: This study is a prospective evaluation of autopsies of 446 individuals from 2011 to 2013 in Brazil. Of that sample, 330 (74%) subjects died from violent deaths and 116 (26%) died naturally. The presence of biliary calculi, previous cholecystectomy, gender, age, ethnicity, body mass index (BMI) and alcohol use were evaluated. RESULTS: In the natural death group, 6.9% (95% CI 3.39 to 13.28) (3.08% of the male subjects and 11.76% of the female subjects) exhibited evidence of gallbladder disease. In the violent death group, only 2.12% (95% CI 0.96 to 4.43) (2.17% of the male subjects and 1.85% of the female subjects) of the subjects exhibited evidence of gallbladder disease. Age was correlated with the prevalence of gallbladder disease, but BMI was correlated with only gallbladder disease in the natural death group. CONCLUSIONS: This population has the lowest prevalence of cholelithiasis in the Americas. Dietary habits, physical activity, ethnicity, alcohol consumption and genetic factors may be responsible for this low prevalence. |
publishDate |
2016 |
dc.date.none.fl_str_mv |
2016-07-01 |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/118025 10.6061/clinics/2016(07)02 |
url |
https://www.revistas.usp.br/clinics/article/view/118025 |
identifier_str_mv |
10.6061/clinics/2016(07)02 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.revistas.usp.br/clinics/article/view/118025/115649 |
dc.rights.driver.fl_str_mv |
Copyright (c) 2016 Clinics info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Copyright (c) 2016 Clinics |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
publisher.none.fl_str_mv |
Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo |
dc.source.none.fl_str_mv |
Clinics; v. 71 n. 7 (2016); 365-369 Clinics; Vol. 71 Núm. 7 (2016); 365-369 Clinics; Vol. 71 No. 7 (2016); 365-369 1980-5322 1807-5932 reponame:Clinics instname:Universidade de São Paulo (USP) instacron:USP |
instname_str |
Universidade de São Paulo (USP) |
instacron_str |
USP |
institution |
USP |
reponame_str |
Clinics |
collection |
Clinics |
repository.name.fl_str_mv |
Clinics - Universidade de São Paulo (USP) |
repository.mail.fl_str_mv |
||clinics@hc.fm.usp.br |
_version_ |
1787713179234598912 |