Prognostic factors for sperm retrieval in non-obstructive azoospermia

Detalhes bibliográficos
Autor(a) principal: Glina, Sidney
Data de Publicação: 2013
Outros Autores: Vieira, Marcelo
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Clinics
Texto Completo: https://www.revistas.usp.br/clinics/article/view/53185
Resumo: Testicular sperm retrieval techniques associated with intracytoplasmic sperm injection have changed the field of male infertility treatment and given many azoospermic men the chance to become biological fathers. Despite the current use of testicular sperm extraction, reliable clinical and laboratory prognostic factors of sperm recovery are still absent. The objective of this article was to review the prognostic factors and clinical use of sperm retrieval for men with non-obstructive azoospermia. The PubMed database was searched for the Medical Subject Headings (MeSH) terms azoospermia, sperm retrieval, and prognosis. Papers on obstructive azoospermia were excluded. The authors selected articles that reported successful sperm retrieval techniques involving clinical, laboratory, or parenchyma processing methods. The selected papers were reviewed, and the prognostic factors were discussed. No reliable positive prognostic factors guarantee sperm recovery for patients with non-obstructive azoospermia. The only negative prognostic factor is the presence of AZFa and AZFb microdeletions.
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spelling Prognostic factors for sperm retrieval in non-obstructive azoospermia AzoospermiaTesticular Sperm RetrievalMale InfertilityReproductive TechniquesPrognosis Testicular sperm retrieval techniques associated with intracytoplasmic sperm injection have changed the field of male infertility treatment and given many azoospermic men the chance to become biological fathers. Despite the current use of testicular sperm extraction, reliable clinical and laboratory prognostic factors of sperm recovery are still absent. The objective of this article was to review the prognostic factors and clinical use of sperm retrieval for men with non-obstructive azoospermia. The PubMed database was searched for the Medical Subject Headings (MeSH) terms azoospermia, sperm retrieval, and prognosis. Papers on obstructive azoospermia were excluded. The authors selected articles that reported successful sperm retrieval techniques involving clinical, laboratory, or parenchyma processing methods. The selected papers were reviewed, and the prognostic factors were discussed. No reliable positive prognostic factors guarantee sperm recovery for patients with non-obstructive azoospermia. The only negative prognostic factor is the presence of AZFa and AZFb microdeletions. Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo2013-01-01info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://www.revistas.usp.br/clinics/article/view/5318510.6061/clinics/2013(Sup01)13Clinics; v. 68 n. spe (2013); 121-124Clinics; Vol. 68 Núm. spe (2013); 121-124Clinics; Vol. 68 No. spe (2013); 121-1241980-53221807-5932reponame:Clinicsinstname:Universidade de São Paulo (USP)instacron:USPenghttps://www.revistas.usp.br/clinics/article/view/53185/57246Glina, SidneyVieira, Marceloinfo:eu-repo/semantics/openAccess2013-04-08T20:47:20Zoai:revistas.usp.br:article/53185Revistahttps://www.revistas.usp.br/clinicsPUBhttps://www.revistas.usp.br/clinics/oai||clinics@hc.fm.usp.br1980-53221807-5932opendoar:2013-04-08T20:47:20Clinics - Universidade de São Paulo (USP)false
dc.title.none.fl_str_mv Prognostic factors for sperm retrieval in non-obstructive azoospermia
title Prognostic factors for sperm retrieval in non-obstructive azoospermia
spellingShingle Prognostic factors for sperm retrieval in non-obstructive azoospermia
Glina, Sidney
Azoospermia
Testicular Sperm Retrieval
Male Infertility
Reproductive Techniques
Prognosis
title_short Prognostic factors for sperm retrieval in non-obstructive azoospermia
title_full Prognostic factors for sperm retrieval in non-obstructive azoospermia
title_fullStr Prognostic factors for sperm retrieval in non-obstructive azoospermia
title_full_unstemmed Prognostic factors for sperm retrieval in non-obstructive azoospermia
title_sort Prognostic factors for sperm retrieval in non-obstructive azoospermia
author Glina, Sidney
author_facet Glina, Sidney
Vieira, Marcelo
author_role author
author2 Vieira, Marcelo
author2_role author
dc.contributor.author.fl_str_mv Glina, Sidney
Vieira, Marcelo
dc.subject.por.fl_str_mv Azoospermia
Testicular Sperm Retrieval
Male Infertility
Reproductive Techniques
Prognosis
topic Azoospermia
Testicular Sperm Retrieval
Male Infertility
Reproductive Techniques
Prognosis
description Testicular sperm retrieval techniques associated with intracytoplasmic sperm injection have changed the field of male infertility treatment and given many azoospermic men the chance to become biological fathers. Despite the current use of testicular sperm extraction, reliable clinical and laboratory prognostic factors of sperm recovery are still absent. The objective of this article was to review the prognostic factors and clinical use of sperm retrieval for men with non-obstructive azoospermia. The PubMed database was searched for the Medical Subject Headings (MeSH) terms azoospermia, sperm retrieval, and prognosis. Papers on obstructive azoospermia were excluded. The authors selected articles that reported successful sperm retrieval techniques involving clinical, laboratory, or parenchyma processing methods. The selected papers were reviewed, and the prognostic factors were discussed. No reliable positive prognostic factors guarantee sperm recovery for patients with non-obstructive azoospermia. The only negative prognostic factor is the presence of AZFa and AZFb microdeletions.
publishDate 2013
dc.date.none.fl_str_mv 2013-01-01
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://www.revistas.usp.br/clinics/article/view/53185
10.6061/clinics/2013(Sup01)13
url https://www.revistas.usp.br/clinics/article/view/53185
identifier_str_mv 10.6061/clinics/2013(Sup01)13
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.revistas.usp.br/clinics/article/view/53185/57246
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
publisher.none.fl_str_mv Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo
dc.source.none.fl_str_mv Clinics; v. 68 n. spe (2013); 121-124
Clinics; Vol. 68 Núm. spe (2013); 121-124
Clinics; Vol. 68 No. spe (2013); 121-124
1980-5322
1807-5932
reponame:Clinics
instname:Universidade de São Paulo (USP)
instacron:USP
instname_str Universidade de São Paulo (USP)
instacron_str USP
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reponame_str Clinics
collection Clinics
repository.name.fl_str_mv Clinics - Universidade de São Paulo (USP)
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